Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA004176 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA004176, RRID:AB_1078412
- Product name
- Anti-RUNX1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human RUNX1, Gene description: runt-related transcription factor 1, Alternative Gene Names: AML1, AMLCR1, CBFA2, PEBP2A2, Validated applications: IHC, ICC, Uniprot ID: Q01196, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references SOX9-positive pituitary stem cells differ according to their position in the gland and maintenance of their progeny depends on context
Systemic deuteration of SCID mice using the water‐isotopologue deuterium oxide (D2O) inhibits tumor growth in an orthotopic bioluminescent model of human pancreatic ductal adenocarcinoma
Keratin filaments mediate the expansion of extra‐embryonic membranes in the post‐gastrulation mouse embryo
Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators
Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen
Impaired Iron Homeostasis and Haematopoiesis Impacts Inflammation in the Ageing Process in Down Syndrome Dementia
Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogenec-KITand amplifies cell proliferation
Expression of RUNX1 Correlates with Poor Patient Prognosis in Triple Negative Breast Cancer
Rizzoti K, Chakravarty P, Sheridan D, Lovell-Badge R
Science Advances 2023;9(40)
Science Advances 2023;9(40)
Systemic deuteration of SCID mice using the water‐isotopologue deuterium oxide (D2O) inhibits tumor growth in an orthotopic bioluminescent model of human pancreatic ductal adenocarcinoma
Jandova J, Galons J, Dettman D, Wondrak G
Molecular Carcinogenesis 2023;62(5):598-612
Molecular Carcinogenesis 2023;62(5):598-612
Keratin filaments mediate the expansion of extra‐embryonic membranes in the post‐gastrulation mouse embryo
Nahaboo W, Eski S, Despin‐Guitard E, Vermeersch M, Versaevel M, Saykali B, Monteyne D, Gabriele S, Magin T, Schwarz N, Leube R, Zwijsen A, Perez‐Morga D, Singh S, Migeotte I
The EMBO Journal 2022;41(7)
The EMBO Journal 2022;41(7)
Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators
O'Hare M, Amarnani D, Whitmore H, An M, Marino C, Ramos L, Delgado-Tirado S, Hu X, Chmielewska N, Chandrahas A, Fitzek A, Heinrich F, Steurer S, Ondruschka B, Glatzel M, Krasemann S, Sepulveda-Falla D, Lagares D, Pedron J, Bushweller J, Liu P, Arboleda-Velasquez J, Kim L
The American Journal of Pathology 2021;191(7):1193-1208
The American Journal of Pathology 2021;191(7):1193-1208
Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen
Li Z, Kuppe C, Ziegler S, Cheng M, Kabgani N, Menzel S, Zenke M, Kramann R, Costa I
Nature Communications 2021;12(1)
Nature Communications 2021;12(1)
Impaired Iron Homeostasis and Haematopoiesis Impacts Inflammation in the Ageing Process in Down Syndrome Dementia
Raha-Chowdhury R, Raha A, Henderson J, Ghaffari S, Grigorova M, Beresford-Webb J, Allinson K, Chakraborty S, Holland A, Zaman S
Journal of Clinical Medicine 2021;10(13):2909
Journal of Clinical Medicine 2021;10(13):2909
Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogenec-KITand amplifies cell proliferation
Debaize L, Jakobczyk H, Avner S, Gaudichon J, Rio A, Sérandour A, Dorsheimer L, Chalmel F, Carroll J, Zörnig M, Rieger M, Delalande O, Salbert G, Galibert M, Gandemer V, Troadec M
Nucleic Acids Research 2018;46(21):11214-11228
Nucleic Acids Research 2018;46(21):11214-11228
Expression of RUNX1 Correlates with Poor Patient Prognosis in Triple Negative Breast Cancer
Mannermaa A, Ferrari N, Mohammed Z, Nixon C, Mason S, Mallon E, McMillan D, Morris J, Cameron E, Edwards J, Blyth K
PLoS ONE 2014;9(6):e100759
PLoS ONE 2014;9(6):e100759
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human breast and liver tissues using HPA004176 antibody. Corresponding RUNX1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol