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- References [433]
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- Product number
- 60330-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- Vimentin antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Vimentin antibody (Cat. #60330-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3H9D1
- Vial size
- 20ul, 150ul
Submitted references RBM15 Enhances 5-Fluorouracil Drug Sensitivity and Suppresses Gastric Cancer Progression by Modulating N6-Methyladenosine Modification of ECT2-Dependent IGF2BP3.
A novel Nilotinib derivative N-12 inhibits the proliferation and migration of colon cancer cells through the EMT signaling pathway.
Graphene Oxide Potentiates Induction Efficiency and Functional Maturation of Induced Mammary Epithelial Cells.
LncRNA VCAN-AS1 Sponges miR-374c-3p to Promote Proliferation, Invasion, Migration, and EMT in Thyroid Cancer.
Stromal cell-derived itaconate promotes endometriosis via macrophage NRF2 and lysosomal pH modulation.
Regulation of EMT and cholangiocarcinoma metastasis by KIN17 through the mTOR signaling pathway.
Fucoidan SPW-05-S2 from Sargassum fusiforme inhibits African swine fever virus replication by blocking PAK2/Talin-1 mediated viral endocytosis and factory formation.
Lithocarpus litseifolius leaf extract alleviate hyperuricemia-induced renal injury by regulating uric acid metabolism and inhibiting the AKT/S6K pathway.
β-catenin mutation reprograms ketone body metabolism to drive hepatocellular carcinoma metastasis and resistance to ketogenic therapy via transcriptional activation of OXCT1.
Activation of the PI3K/AKT pathway by EDIL3 induces EMT and promotes tumor progression in clear cell renal cell carcinoma.
A new candidate tumor suppressor tRF-Ser inhibits gastric cancer progression by regulating the CNBP/HSPA8 axis.
USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.
Tannic Acid Achieves Rapid Scar-Free Corneal Healing by Chelating Excess Copper to Suppress Aberrant LOX-Mediated Fibrosis.
SPIONs-labeled hUCMSCs for in vitro safety analysis and in vivo tracking in scarred monkey uteri.
Suppression of LTBP1 enhances the sensitivity of bladder cancer to cisplatin.
λ-Carrageenan inhibits African swine fever virus infection potentially through its interaction with the viral envelope protein CD2v.
Basement membrane-associated gene P3H2 regulates osteosarcoma progression and epithelial-mesenchymal transition through AKT/mTOR signaling axis.
CMTM6 promotes synovial proliferation and macrophage polarization by preventing ubiquitination of TAK1 in rheumatoid arthritis.
Narirutin Reprograms Fatty Acid Metabolism and Inhibits Tumorigenesis via Downregulating ADORA3 Expression in Colorectal Cancer.
7,8-Dihydroxyflavone Suppresses Experimental Pulmonary Fibrosis by Inhibiting Fibroblast-to-Myofibroblast Transformation and Epithelial-Mesenchymal Transition.
RADA16 and SAAP148 Peptide-Modified Collagen Self-Assembled Hydrogels for Accelerated Healing of Infected Wounds.
CGRP/TSP1 Signaling Dampens Corneal Inflammation and Fibrosis by Targeting A2M During Corneal Stromal Wound Healing.
Glutaminase promotes the malignant progression of esophageal squamous cell carcinoma via TGF-β canonical and noncanonical.
Improving erectile function in diabetic male mice by rescuing depalmitoylated FBP1 to reduce cavernosal lactate.
Discovery of XRF-1021, a 2,4-disubstituted-5-fluoropyrimidine derivative as a homeodomain-interacting protein kinase 2 inhibitor for the treatment of chronic kidney disease.
G3BP2 facilitates abnormal activation of fibroblast-like synoviocytes through p53 signaling pathway in rheumatoid arthritis.
PGK1 Persulfidation Promotes the Proliferation and Metastasis of Breast Cancer.
Immunohistochemical Evidence of Telocytic Stroma Associated with Tumor Grade and Acinar Heterogeneity in Prostate Cancer.
Multi-omics analysis reveals RBPJ-mediated regulation of EGF/ACTN2/MYPN/COL21A1 in fibroblast during oviduct functional remodeling of duck.
Mitochondrial uncoupling sensitizes gastric cancer cells to elesclomol-induced cuproptosis via FDX1/DLAT upregulation.
EP300 attenuates ferroptosis and stimulates proliferation, migration, and fibrosis of keloid fibroblasts via YY1/GPX4 axis.
Matrix-free cryo-microneedles array patch for 3D hair follicle organoids delivery and rapid hair regeneration.
Pro-tumourigenic effects of DCAF13 on the progression of colorectal cancer.
UCHL3 Promotes Triple-Negative Breast Cancer Metastatic Potential Through Enhancing Cell Migration and Invasion.
Extracellular vesicles derived from senescent hepatocytes drive pan-cancer metastasis in aging.
A conserved re-epithelialization program underlies malignancy in pancreatic ductal adenocarcinoma.
IL-5 promotes airway remodeling in asthma by mediating epithelial-mesenchymal transition via the AKT/NLRP3 pathway.
CRYM suppresses glioblastoma progression by inhibiting the TGFβ1/Smad-EMT signaling pathway.
ETV1 transcriptional manipulation of KIFC1 regulates the progression of pancreatic cancer.
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
Inhibition of Mettl3 alleviates low-dose cisplatin-induced renal fibrosis and enhances the chemotherapeutic efficacy in mouse models of cancer.
Abnormally Activated MNX1 Promotes Tumor Growth and Osimertinib Resistance and Predicts Survival in EGFR-Mutant Lung Adenocarcinoma.
Identification of Key Genes Involved in the Occurrence and Development of Endometrial Cancer.
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
System Analysis Identifies MYBL2 As a Novel Oncogene Target for Metastatic Prostate Cancer.
Identification of CAF signature genes and construction of CAF-based risk signature in hepatocellular carcinoma by multi-omics analysis.
CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.
MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.
MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma.
Enhancing pancreatic cancer treatment: the role of H101 oncolytic virus in irreversible electroporation.
Screening and identification of protein 29 of Echinococcus granulosus interacting molecules.
Ciprofol exerts anti-tumour effects in hepatocellular carcinoma through the Raf-MEK-ERK signalling pathway.
The Down-Regulation of Lactoferrin Expression Induced by Cigarette Smoke can Induce Ferroptosis in COPD.
Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer.
Dietary addition of magnesium hydride nanoparticles: a breakthrough in combating high-fat diet-induced chronic kidney disease.
TKT regulates the pentose phosphate pathway via RBKS to promote epithelial-mesenchymal transition during AML progression.
Titanium surface modified with nanostructure mimicking the surface of natural cementum up-regulated epithelial expression of integrin β4 and enhanced the attachment of the transmucosal gingiva.
Endothelial HMGB1-AIM2 axis worsens myocardial ischemia-reperfusion injury by regulating endothelial pyroptosis.
Rottlerin inhibits PKCδ to attenuate pulmonary fibrosis by suppressing NLRC4/ASC-mediated pyroptosis.
Geniposide alleviates kidney fibrosis by targeting STAT3-HK2-mediated glycolysis.
KAT2A-H3K79succ-Mediated SH2B3 Upregulation Promotes TNBC Metastasis Through Diminishing the Ubiquitin-Dependent Degradation of Vimentin.
FUT8 promotes HDM-induced glycolysis, epithelial-mesenchymal transition and inflammation in bronchial epithelial cells by inducing N-glycosylation modification of GLUT1.
Pan-cancer analysis of role of LOXL4 and experiment validation in osteosarcoma.
Hsa_circRNA_0101125 Promotes Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma via miR-143-3p/ZNF148 Axis.
Liver metastasis or peritoneal metastasis: single-cell RNA sequencing reveals the organotropism in colorectal cancer is driven by distinct partial-EMT processes.
Mitochondrial dysfunction-associated cellular senescence is partially involved in bleomycin-induced pulmonary fibrosis in mice.
Identification and validation of BCL11A as a neural and immune vulnerability factor in pancreatic adenocarcinoma.
Kindlin-1 promotes mitophagy by inhibiting PINK1 degradation to enhance hepatocellular carcinoma progression and modulates sensitivity to donafenib.
The E3 ubiquitin ligase TRIM31 enhances the progression of esophageal cancer through the ubiquitination of BBOX1.
TGF-β1 mediates epithelial-mesenchymal transition in interstitial cystitis through the regulation of ROCK.
Neutrophil extracellular traps regulate LDHA expression to promote colorectal cancer liver metastasis.
MiR-106b-5p promotes gastric cancer progression by directly targeting the tumor suppressor RBL2.
Scutellarin triggers ferroptosis in ovarian cancer cells via inhibiting AKT/mTOR and JAK2/STAT3 pathways.
SGK1 inhibits oxidative injury and extracellular matrix degradation by activating the GSK-3β (Ser9)/Fyn/NRF2 pathway in pelvic organ prolapse.
Lipocalin 2 Facilitates the Initial Compromise of the Blood-Brain Barrier Integrity in Chronic Cerebral Hypoperfusion.
METTL3-mediated m6A modification of PAK6 drives cervical cancer progression through activating MAPK14.
CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.
Saliva-derived extracellular vesicles: a promising therapeutic approach for salivary gland fibrosis.
Piezo1 regulates actin cytoskeleton remodeling to drive EMT in cervical cancer through the RhoA/ROCK1/PIP2 signaling pathway.
Annexin A2 Contributes to Release of Extracellular Vimentin in Response to Inflammation.
SOX4 as a Key Oncogene Driving Tumor Invasion in Retinoblastoma.
UBE2C mediates follicular thyroid carcinoma invasion and metastasis via K29-Specific vimentin ubiquitination.
Berberine Inhibits Migration and Apoptosis of Rat Podocytes in Diabetic Nephropathy via the Novel lncRNA LOC102549726 Related Pathway.
The role of fibromodulin in myocardial fibrosis in a diabetic cardiomyopathy rat model.
Enhanced Vascular Smooth Muscle Cell and Extracellular Matrix Repair Using a Metal-Organic Framework-Based Co-Delivery System for Abdominal Aortic Aneurysm Therapy.
The roles of HOXB9 and MMP12 in proliferation, migration, and invasion of human laryngeal cancer cells LCC and TU212.
NEAT1 promotes the perineural invasion of pancreatic cancer via the E2F1/GDNF axis.
Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis.
Isoliquiritigenin attenuates tumor progression and PD-L1 expression by inhibiting the phosphorylation of STAT3 in melanoma.
Astilbin Alleviates Radiation-Induced Pulmonary Fibrosis via circPRKCE Targeting the TGF-β/Smad7 Pathway to Inhibit Epithelial-Mesenchymal Transition.
Metformin Attenuates Partial Epithelial-Mesenchymal Transition in Salivary Gland Inflammation via PI3K/Akt/GSK3β/Snail Signaling Axis.
Glycated ECM Derived Carbon Dots Inhibit Tumor Vasculogenic Mimicry by Disrupting RAGE Nuclear Translocation and Its Interaction With HMGB1.
Apelin-13 Protects Against Airway Inflammation, Oxidative Stress, and Epithelial-Mesenchymal Transition in a Chronic Asthma Model.
Omentin-1 attenuates atrial fibrillation via Src/PI3K/Akt signaling-mediated anti-fibrotic effects in cardiac fibroblasts.
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Ancestry-linked stromal variations impact breast epithelial cell invasion.
The upregulation of TNKS1 drives the phenotypic switching of vascular smooth muscle cells in aortic dissection through the activation of ferroptosis.
METTL3 Modulates Radiation-Induced Cardiac Fibrosis via the Akt/mTOR Pathway.
Novel insights into human CRISP2: localization in reproductive tissues and sperm, and molecular characterization†.
Comprehensive multi-omics analysis of histone acetylation modulators identifies ASH1L as a novel aggressive marker for osteosarcoma.
Role of the USP7/FOXO3A axis in environmentally relevant doses of arsenic-induced lung carcinogenesis: Insights from bioinformatics analysis and model of human epithelial cell malignant transformation.
Increased SUMO-activating enzyme subunit 1 promotes glycolysis and fibrotic phenotype of diabetic nephropathy.
Neoadjuvant Chemotherapy With Cisplatin Up-Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14-Mediated EMT Activation.
P300-dependent acetylation of the FOXQ1 complex activates super-enhancers to promote colorectal cancer proliferation and metastasis.
Systematic identification of SNCA as a key gene in ischemic cardiomyopathy via integrated weighted gene co-expression network analysis and experimental validation.
GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2.
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Elevated SGO2 expression in lung adenocarcinoma promotes migration and invasion via MAD2 and correlates with poor prognosis.
CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism.
The molecular subtype based on cell cycle-related gene signature predicts the prognosis and chemotherapy and immunotherapy response in gastric cancer.
ERβ-regulated circATP2B1/miR-204-3p/TWIST1 positive feedback loop facilitates epithelial to mesenchymal transition in clear cell renal cell carcinoma.
Proteomics analysis revealed the therapeutic role of adipose-derived mesenchymal stem cells on radiation-induced colorectal fibrosis in rats.
NAP1L5 promotes epithelial-mesenchymal transition by regulating PEG10 expression in acute myeloid leukaemia.
Sang-Bai-Pi extract and its constituent regiafuran C ameliorate renal fibrosis through TGF-β/Smad and Wnt/β-catenin signaling pathways.
Mechanistic insights into the treatment of pulmonary fibrosis with bioactive components from traditional chinese medicine via matrix stiffness-mediated EMT.
Xihuang pill suppresses breast cancer malignancy by inhibiting TGF-β signaling and acquires chemotherapy benefits.
3D printed biomimetic bilayer limbal implants for regeneration of the corneal structure in limbal stem cell deficiency.
Pirfenidone alleviates interstitial lung disease in mice by inhibiting neutrophil extracellular trap formation and NLRP3 inflammasome activation.
Inhibition of Myocardin-related Transcription Factor A Ameliorates Pathological Remodeling of the Pressure-loaded Right Ventricle.
Regulation of pancreatic cancer cells by suppressing KIN17 through the PI3K/AKT/mTOR signaling pathway.
CB-MNCs@ CS/HEC/GP promote wound healing in aged murine pressure ulcer model.
Ultrasound-guided renal subcapsular transplantation of mesenchymal stem cells for treatment of acute kidney injury in a minipig model: safety and efficacy evaluation.
The inhibition of ZC3H13 attenuates G2/M arrest and apoptosis by alleviating NABP1 m6A modification in cisplatin-induced acute kidney injury.
Harnessing 2D and 3D human endometrial cell culture models to investigate SARS-CoV-2 infection in early pregnancy.
A novel piperine derivative HJJ_3_5 inhibits colorectal cancer progression by modulating EMT signaling pathways.
B7-H3 enhances the malignant phenotype of colorectal cancer by activating the Wnt/β-catenin pathway mediated by CYP1B1.
TM4SF1 as a Prognostic Biomarker and Therapeutic Target in Cervical Cancer.
Adipose-derived mesenchymal stem cell exosomes protect keratinocytes from high-glucose injury by modulating KEAP1/NRF2/HO-1 axis.
Cinobufagin Directly Targets PDE4D to Disrupt Fibroblast-Dendritic Cell Crosstalk in Atopic Dermatitis.
Exosome-derived Menin from cancer-associated fibroblasts promotes gastric cancer progression by activating the HSPA6/JNK/JunD pathway and inducing EMT.
PLS3 Is a Prognostic Biomarker and Correlates with Immune Infiltrates in Head and Neck Squamous Cell Carcinoma.
Alpha-1 Antitrypsin Mediates Spontaneous Resolution of Acute Gouty Inflammation Via Inhibiting Caspase 3/GSDME-dependent Macrophage Pyroptosis.
Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells.
HIF-1α mediates mitochondrial damage by down-regulating ALKBH7 expression to promote the aberrant activation of FLS in rheumatoid arthritis.
Elastin-like polypeptide and triclosan-modified PCL membrane provides aseptic protection in tissue regeneration.
Thermosensitive hydrogel composite with si-Cx43 nanoparticles and anti-VEGF agent for synergistic treatment of diabetic retinopathy.
Newcastle disease virus promotes spreading infection through vimentin-dependent tight junction injury mediated by MLC/p-MLC activation.
Circ847 upregulation via CAFs suppresses salivary adenoid cystic carcinoma progression through VIM-EMT.
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer.
DDX18 promotes growth and metastasis of hepatocellular carcinoma via activating EMT and MAPK signaling.
Inhibition of macrophage extracellular traps by Metrnl/IL-41 suppresses airway remodeling in asthma.
Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma.
POC1A induces epithelial-mesenchymal transition to promote growth and metastasis through the STAT3 signaling pathway in triple-negative breast cancer.
SOX17 Prevents Endothelial-Mesenchymal Transition of Pulmonary Arterial Endothelial Cells in Pulmonary Hypertension through Mediating TGF-β/Smad2/3 Signaling.
Plasma-Derived Exosomal i-tRF-LeuCAA as Biomarker for Glioma Diagnosis and Promoter of Epithelial-Mesenchymal Transition via TPM4 Regulation.
tRF-34-P4R8YP9LON4VHM Promotes Hepatocellular Carcinoma Progression and Tumour Cell-Induced Angiogenesis via the MEK/ERK Pathway.
Elevated CD47 Expression Impairs Elimination of Photoaged Fibroblasts by Macrophages and Serves as a Potential Biomarker for Photoaging.
Bioinformatics Combined With Biological Experiments to Identify the Pathogenetic Link of Type 2 Diabetes for Breast Cancer.
The CD163 + tissue-infiltrating macrophages regulate ferroptosis in thyroid-associated ophthalmopathy orbital fibroblasts via the TGF-β/Smad2/3 signaling pathway.
A Hybrid Manganese Nanoparticle Simultaneously Eliminates Cancer Stem Cells and Activates STING Pathway to Potentiate Cancer Immunotherapy.
Huaier suppresses cell viability, migration and invasion in human non-small cell lung cancer via lncRNA DLEU2/miR-212-5p/ELF3 axis.
Melatonin serves as a novel treatment in bladder fibrosis through TGF-β1/Smad and EMT.
Highly Ordered Nanotube-Like Microstructure on Titanium Dental Implant Surface Fabricated via Anodization Enhanced Cell Adhesion and Migration of Human Gingival Fibroblasts.
Localized Administration of Bcar3 siRNA via Nano-Self-Assembly to Treat Idiopathic Pulmonary Fibrosis by Disrupting Macrophage-Fibroblast Crosstalk.
Progerin Inhibits the Proliferation and Migration of Melanoma Cells by Regulating the Expression of Paxillin.
Cross-border regulation of the STK39/MAPK14 pathway by Lycium barbarum miR166a to inhibit triple-negative breast cancer.
MiR-383-5p inhibits the proliferation and migration of lung adenocarcinoma cells by targeting SHMT2.
DOK1 facilitates the advancement of ccRCC.
MLPH regulates EMT in pancreatic adenocarcinoma through the PI3K-AKT signaling pathway.
ITGAX promotes gastric cancer progression via epithelial-mesenchymal transition pathway.
NUP155 and NDC1 interaction in NSCLC: a promising target for tumor progression.
The mechanism of PDE7B inhibiting the development of hepatocellular carcinoma through oxidative stress.
Identification and verification of the optimal feature genes of ferroptosis in thyroid-associated orbitopathy.
The long non-coding RNA CCAT1 promotes erlotinib resistance in cholangiocarcinoma by inducing epithelial-mesenchymal transition via the miR-181a-5p/ROCK2 axis.
Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma.
Characterization and arbovirus susceptibility of cultured CERNI cells derived from sika deer (Cervus nippon).
Recombinant humanized type I collagen remodels decidual immune microenvironment at maternal-fetal interface by modulating Th17/Treg imbalance.
Mitochondrial dysfunction-associated alveolar epithelial senescence is involved in CdCl(2)-induced COPD-like lung injury.
Cigarette smoke extract induces malignant transformation and DNA damage via c-MET phosphorylation in human bronchial epithelial cells.
LncRNA HIF1A-AS2 promotes triple-negative breast cancer progression and paclitaxel resistance via MRPS23 protein.
Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway: Screening of natural products using WGCNA and CMAP platforms.
Anti-cancer effects of nitazoxanide in epithelial ovarian cancer in-vitro and in-vivo.
Multi-omics analysis reveals BZW1's regulation of EMT via the Wnt pathway in lung adenocarcinoma.
Single-cell analysis reveals alternations between the aged and young mice prostates.
SMYD2 Promotes Calcium Oxalate-Induced Glycolysis in Renal Tubular Epithelial Cells via PTEN Methylation.
Selenium supplementation elevated SELENBP1 to inhibit fibroblast activation in pulmonary arterial hypertension.
Chromosome 8q24 amplification associated with human hepatocellular carcinoma predicts MYC/ZEB1/MIZ1 transcriptional regulation.
A living organoid biobank of patients with Crohn's disease reveals molecular subtypes for personalized therapeutics.
NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.
Immunohistochemical and ultrastructural identification of telocytes in the infantile hemangioma.
NEU4-mediated desialylation enhances the activation of the oncogenic receptors for the dissemination of ovarian carcinoma.
Effect and underlying mechanism of a photochemotherapy dual-function nanodrug delivery system for head and neck squamous cell carcinoma.
Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis.
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
Engineered keratin/bFGF hydrogel to promote diabetic wound healing in rats.
LncRNA-SNHG5 mediates activation of hepatic stellate cells by regulating NF2 and Hippo pathway.
Integrative analysis of metabolism subtypes and identification of prognostic metabolism-related genes for glioblastoma.
Comprehensive analysis of zinc and ring finger 3 in prognostic value and pan-cancer immunity.
TRPC6 Knockout Alleviates Renal Fibrosis through PI3K/AKT/GSK3B Pathway.
Expression, characterization and antivascular activity of amino acid sequence repeating collagen hexadecapeptide.
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Kokusaginine attenuates renal fibrosis by inhibiting the PI3K/AKT signaling pathway.
OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway.
Endothelial-to-Mesenchymal Transition in an Hereditary Hemorrhagic Telangiectasia-like Pediatric Case of Multiple Pulmonary Arteriovenous Malformations.
ISG15 promotes tumor progression via IL6/JAK2/STAT3 signaling pathway in ccRCC.
MEX3A promotes colorectal cancer migration, invasion and EMT via regulating the Wnt/β-catenin signaling pathway.
Study on the mechanism of S100A4-mediated cancer oncogenesis in uveal melanoma cells through the integration of bioinformatics and in vitro experiments.
Lysine acetyltransferase 14 mediates TGF-β-induced fibrosis in ovarian endometrioma via co-operation with serum response factor.
Direct contact between tumor cells and platelets initiates a FAK-dependent F3/TGF-β positive feedback loop that promotes tumor progression and EMT in osteosarcoma.
FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease.
Expression analysis and biological regulation of silencing regulatory protein 6 (SIRT6) in cutaneous squamous cell carcinoma.
Silencing SPP1 in M2 macrophages inhibits the progression of castration-resistant prostate cancer via the MMP9/TGFβ1 axis.
Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
A new mechanism in negative pressure wound therapy: interleukin-17 alters chromatin accessibility profiling.
Pro-osteogenic role of interleukin-22 in calcific aortic valve disease.
TESC acts as a prognostic factor and promotes epithelial-mesenchymal transition progression in esophageal squamous carcinoma.
Transcriptomics Reveals the Mechanism of Platycodin D Targeting TGFβ for Anti-Lung Cancer Activity.
Nuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1.
Chitosan inhibits vascular intimal hyperplasia via LINC01615/MIR-185-5p/PIK3R2 signaling pathway.
EMP3 as a prognostic biomarker correlates with EMT in GBM.
CSTB accelerates the progression of hepatocellular carcinoma via the ERK/AKT/mTOR signaling pathway.
Targeting blood brain barrier-Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats.
JAM2 is a prognostic biomarker and inhibits proliferation, metastasis and epithelial-mesenchymal transition in lung adenocarcinoma.
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway.
High CD133 expression in proximal tubular cells in diabetic kidney disease: good or bad?
Bromodomain containing 4 inhibition combats gastric precancerous lesions via modulating macrophage polarization.
The unfolded protein response sensor PERK mediates mechanical stress-induced maturation of focal adhesion complexes in glioblastoma cells.
Adaptor protein CEMIP reduces the chemosensitivity of small cell lung cancer via activation of an SRC-YAP oncogenic module.
G protein-coupled receptor kinase 2 as a novel therapeutic target for gland fibrosis of Sjögren's syndrome.
Circular RNA circWBSCR22 facilitates colorectal cancer metastasis by enhancing CHD4's protein stability.
Hypoxia-driven heterogeneous expression of α5 integrin in glioblastoma stem cells is linked to HIF-2α.
Expression of SARS-CoV-2 entry molecules ACE2, NRP1, TMPRSS2, and FURIN in the reproductive tissues of male macaques.
RRM2 Regulates Hepatocellular Carcinoma Progression Through Activation of TGF-β/Smad Signaling and Hepatitis B Virus Transcription.
OCTN2 expression and function in the Sertoli cells of testes from patients with non-obstructive azoospermia.
Ancestry-linked stromal variations impact breast epithelial cell invasion.
IGFALS suppresses hepatocellular carcinoma progression by stabilizing PPAR-γ.
Identification of UNC5B as a novel aggressive biomarker for osteosarcoma based on basement membrane genes.
miR-200a-3p inhibits the PDGF-BB-induced proliferation of VSMCs by affecting their phenotype-associated proteins.
Microbial imidazole propionate affects glomerular filtration rate in patients with diabetic nephropathy through association with HSP90α.
PlexinA1 promotes gastric cancer migration through preventing MICAL1 protein ubiquitin/proteasome-mediated degradation in a Rac1-dependent manner.
Deubiquitinase OTUD6a drives cardiac inflammation and hypertrophy by deubiquitination of STING.
Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis.
Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction.
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
Melt electrowriting-printed peritoneal scaffold prevents peritoneal adhesion and facilitates peritoneal repair.
Caffeic acid phenethyl ester suppresses metastasis of breast cancer cells by inactivating FGFR1 via MD2.
Sevoflurane Improves Ventricular Conduction by Exosomes Derived from Rat Cardiac Fibroblasts After Hypothermic Global Ischemia-Reperfusion Injury.
Expression profiles of α-synuclein in cortical lesions of patients with FCD IIb and TSC, and FCD rats.
Tocilizumab (monoclonal anti-IL-6R antibody) reverses anlotinib resistance in osteosarcoma.
UCHL3 promotes hepatocellular carcinoma cell migration by de-ubiquitinating and stabilizing Vimentin.
Bioinformatics prediction and experimental verification of a novel microRNA for myocardial fibrosis after myocardial infarction in rats.
The NLRP11 Protein Bridges the Histone Lysine Acetyltransferase KAT7 to Acetylate Vimentin in the Early Stage of Lung Adenocarcinoma.
AZGP1 activation by lenvatinib suppresses intrahepatic cholangiocarcinoma epithelial-mesenchymal transition through the TGF-β1/Smad3 pathway.
DKK1 Promotes Epithelial-Mesenchymal Transition and Cisplatin Resistance in Gastric Cancer via Activation of the PI3K/AKT Pathway.
FAM3A reshapes VSMC fate specification in abdominal aortic aneurysm by regulating KLF4 ubiquitination.
Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway.
ACLY promotes gastric tumorigenesis and accelerates peritoneal metastasis of gastric cancer regulated by HIF-1A.
DACH1 regulates macrophage activation and tumour progression in hypopharyngeal squamous cell carcinoma.
Enhanced Mitophagy in Cholesteatoma Epithelial Cells.
LncBIRC3-OT promotes the malignant progression of glioma by interacting with RELA to upregulate stanniocalcin-1 expression.
Epinodosin suppresses the proliferation, invasion, and migration of esophageal squamous cell carcinoma by mediating miRNA-143-3p/Bcl-2 axis.
Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells.
Discovery of a novel dual-target inhibitor of CDK12 and PARP1 that induces synthetic lethality for treatment of triple-negative breast cancer.
Hsa_circ_0009092/miR-665/NLK signaling axis suppresses colorectal cancer progression via recruiting TAMs in the tumor microenvironment.
Metformin Attenuates TGF-β1-Induced Fibrosis in Salivary Gland: A Preliminary Study.
ZD6474 attenuates TGF-β1-induced fibrosis in human Tenon fibroblasts and inhibits neovascularization via AKT-mTOR signaling pathway.
Lycopene inhibits endothelial-to-mesenchymal transition of choroidal vascular endothelial cells in laser-induced mouse choroidal neovascularization.
Nicotine exposure exacerbates silica-induced pulmonary fibrosis via STAT3-BDNF-TrkB-mediated epithelial-mesenchymal transition in alveolar type II cells.
The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII.
ZD6474 Attenuates Fibrosis and Inhibits Neovascularization in Human Pterygium by Suppressing AKT-mTOR Signaling Pathway.
Simple, Fast, and Efficient Method for Derivation of Dermal Fibroblasts From Skin Biopsies.
Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation.
Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling.
FGF4 Promotes Skin Wound Repair through p38 MAPK and GSK3β-Mediated Stabilization of Slug.
Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway.
High glucose promotes the progression of colorectal cancer by activating the BMP4 signaling and inhibited by glucagon-like peptide-1 receptor agonist.
Activation of Piezo1 promotes osteogenic differentiation of aortic valve interstitial cell through YAP-dependent glutaminolysis.
ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11.
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Astragaloside IV Blunts Epithelial-Mesenchymal Transition and G2/M Arrest to Alleviate Renal Fibrosis via Regulating ALDH2-Mediated Autophagy.
Single-cell RNA sequencing reveals that VIM and IFITM3 are vital targets of Dengzhan Shengmai capsule to protect against cerebral ischemic injury.
Cancer-Associated Fibroblasts Promote Radioresistance of Breast Cancer Cells via the HGF/c-Met Signaling Pathway.
PLAGL2 increases adriamycin resistance and EMT in breast cancer cells by activating the Wnt pathway.
SERPINA5 may promote the development of preeclampsia by disruption of the uPA/uPAR pathway.
LncRNA NR120519 Blocks KRT17 to Promote Cell Proliferation and Migration in Hypopharyngeal Squamous Carcinoma.
Embryonic 6:2 FTOH exposure causes reproductive toxicity by disrupting the formation of the blood-testis barrier in offspring mice.
LncRNA BCAR4 promotes migration, invasion, and chemo-resistance by inhibiting miR-644a in breast cancer.
The miR-103a-3p/TGFBR3 axis regulates TGF-β-induced orbital fibroblast activation and fibrosis in thyroid-eye disease.
Huntingtin-associated protein 1 is a potential tumor suppressor for gastric cancer.
Umbilical cord mesenchymal stem cell-derived exosomes reverse endometrial fibrosis by the miR-145-5p/ZEB2 axis in intrauterine adhesions.
SPON2 promotes the bone metastasis of lung adenocarcinoma via activation of the NF-κB signaling pathway.
Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics.
Downregulation of CYRI-B promotes migration, invasion and EMT by activating the Rac1-STAT3 pathway in gastric cancer.
SOX10 promotes the malignant biological behavior of basal-like breast cancer cells by regulating EMT process.
PLCB1 Enhances Cell Migration and Invasion in Gastric Cancer Via Regulating Actin Cytoskeletal Remodeling and Epithelial-Mesenchymal Transition.
Radioprotective efficacy of Astilbin in mitigating radiation-induced lung injury through inhibition of p53 acetylation.
FAM107A as a tumor suppressor in esophageal squamous carcinoma inhibits growth and metastasis.
Isoliquiritigenin suppresses the progression of malignant melanoma via targeting H2A.Z.1-E2F1 pathway.
Aberrant acetylated modification of FGF21‑KLB signaling contributes to hepatocellular carcinoma metastasis through the β‑catenin pathway.
Dipeptidase‑2 is a prognostic marker in lung adenocarcinoma that is correlated with its sensitivity to cisplatin.
Neonatal-Tissue-Derived Extracellular Vesicle Therapy (NEXT): A Potent Strategy for Precision Regenerative Medicine.
Glutamine and amino acid metabolism as a prognostic signature and therapeutic target in endometrial cancer.
SMC1A facilitates gastric cancer cell proliferation, migration, and invasion via promoting SNAIL activated EMT.
CSF2 upregulates CXCL3 expression in adipocytes to promote metastasis of breast cancer via the FAK signaling pathway.
Inhibition of Transglutaminase 2 Reduces Peritoneal Injury in a Chlorhexidine-Induced Peritoneal Fibrosis Model.
FSBP suppresses tumor cell migration by inhibiting the JNK pathway.
miR-138-5p Inhibits the Growth and Invasion of Glioma Cells by Regulating WEE1.
Plasma-Based Metabolomics Profiling of High-Risk Human Papillomavirus and their Emerging Roles in the Progression of Cervical Cancer.
ARL4C Regulates the Progression of Clear Cell Renal Cell Carcinoma by Affecting the Wnt/β-Catenin Signaling Pathway.
LASS2 impairs proliferation of glioma stem cells and migration and invasion of glioma cells mainly via inhibition of EMT and apoptosis promotion.
Down-regulation of MSMO1 promotes the development and progression of pancreatic cancer.
Manpixiao Decoction Halted the Malignant Transformation of Precancerous Lesions of Gastric Cancer: From Network Prediction to In-Vivo Verification.
Deciphering the Mechanism of Bushen Huoxue Decotion on Decidualization by Intervening Autophagy via AMPK/mTOR/ULK1: A Novel Discovery for URSA Treatment.
Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury.
Protein-protein interactions between RUNX3 and ZEB1 in chronic lung injury induced by methamphetamine abuse.
Irradiation enhances the malignancy-promoting behaviors of cancer-associated fibroblasts.
MiR-29b-3p Inhibits Migration and Invasion of Papillary Thyroid Carcinoma by Downregulating COL1A1 and COL5A1.
BCAT1 promotes lung adenocarcinoma progression through enhanced mitochondrial function and NF-κB pathway activation.
Effect of Baricitinib on the epithelial-mesenchymal transition of alveolar epithelial cells induced by IL-6.
HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway.
FTO Inhibits Epithelial Ovarian Cancer Progression by Destabilising SNAI1 mRNA through IGF2BP2.
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling.
CircRNA Samd4 induces cardiac repair after myocardial infarction by blocking mitochondria-derived ROS output.
Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.
FGF2 isoforms play distinct roles in tubular epithelial-to-mesenchymal transition in diabetic nephropathy.
Single-Cell RNA Sequencing Technology Revealed the Pivotal Role of Fibroblast Heterogeneity in Angiotensin II-Induced Abdominal Aortic Aneurysms.
Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1.
FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression.
Tofacitinib May Inhibit Myofibroblast Differentiation from Rheumatoid-Fibroblast-like Synoviocytes Induced by TGF-β and IL-6.
Transcriptomic investigation of the effects of TDCPP on PC12 and GC2 cells with experimental validation.
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.
P16ink4a overexpression ameliorates cardiac remodeling of mouse following myocardial infarction via CDK4/pRb pathway.
Green tea peptides ameliorate diabetic nephropathy by inhibiting the TGF-β/Smad signaling pathway in mice.
Deactivation of AKT/GSK-3β-mediated Wnt/β-catenin pathway by silencing of KIF26B weakens the malignant behaviors of non-small cell lung cancer.
Targeting RPL23 restores chemosensitivity of cisplatin-resistant ovarian carcinoma by inhibiting EMT.
Effects of titanium dioxide microparticles and nanoparticles on cytoskeletal organization, cell adhesion, migration, and proliferation in human gingival fibroblasts in the presence of lipopolysaccharide.
Inhibition of FAM83D displays antitumor effects in glioblastoma via down-regulation of the AKT/Wnt/β-catenin pathway.
Lysyl oxidase-like 2 inhibitor rescues D-galactose-induced skeletal muscle fibrosis.
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
SND1 acts as a functional target of miR-330-5p involved in modulating the proliferation, apoptosis and invasion of colorectal cancer cells.
The presence of living endometrial cells in ovarian endometriotic cyst fluid may contribute to the recurrence of endometriosis after surgical excision of endometriomas.
HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance.
Melatonin and verteporfin synergistically suppress the growth and stemness of head and neck squamous cell carcinoma through the regulation of mitochondrial dynamics.
HSP90AB1 Promotes the Proliferation, Migration, and Glycolysis of Head and Neck Squamous Cell Carcinoma.
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
Nc886 promotes renal cancer cell drug-resistance by enhancing EMT through Rock2 phosphorylation-mediated β-catenin nuclear translocation.
Mesenchyme homeobox 2 has a cancer-inhibiting function in breast carcinoma via affection of the PI3K/AKT/mTOR and ERK1/2 pathways.
Activation of GRP78 ATPase suppresses A549 lung cancer cell migration by promoting ITGB4 degradation.
Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis.
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Müller Glia maintain their regenerative potential despite degeneration in the aged zebrafish retina.
The interferon regulatory factor 6 promotes cisplatin sensitivity in colorectal cancer.
HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis.
A mesenchymal to epithelial switch in Fgf10 expression specifies an evolutionary-conserved population of ionocytes in salivary glands.
Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.
Qingjie Fuzheng Granule Inhibits EMT and Induces Autophagy in Colorectal Cancer via mTOR Signaling Pathways.
Ginsenoside CK Inhibits TGF-β-Induced Epithelial-Mesenchymal Transition in A549 Cell via SIRT1.
KMT5A downregulation participated in High Glucose-mediated EndMT via Upregulation of ENO1 Expression in Diabetic Nephropathy.
P68 RNA Helicase facilitates Breast Cancer progression by promoting Proliferation and Migration via PDGFR-β/AR axis.
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation.
Sorafenib derivatives-functionalized gold nanoparticles confer protection against tumor angiogenesis and proliferation via suppression of EGFR and VEGFR-2.
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-AKT signaling pathway as revealed by network pharmacology and in vitro experimental verification.
miR-30b-5p inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting GALNT7 via the EGFR/PI3K/AKT pathway.
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.
CCL21 activation of the MALAT1/SRSF1/mTOR axis underpins the development of gastric carcinoma.
Trim47 overexpression correlates with poor prognosis in gastric cancer.
Bone marrow stem cells secretome accelerates simulated birth trauma-induced stress urinary incontinence recovery in rats.
Long non‑coding RNA MIR4435‑2HG promotes the progression of head and neck squamous cell carcinoma by regulating the miR‑383‑5p/RBM3 axis.
SOD3 deficiency induces liver fibrosis by promoting hepatic stellate cell activation and epithelial-mesenchymal transition.
LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition.
In Silico, In Vitro, and In Vivo Analysis Identifies Endometrial Circadian Clock Genes in Recurrent Implantation Failure.
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
Overexpression of SERPINA3 promotes tumor invasion and migration, epithelial-mesenchymal-transition in triple-negative breast cancer cells.
LncRNA LPAL2/miR-1287-5p/EGFR Axis Modulates TED-Derived Orbital Fibroblast Activation Through Cell Adhesion Factors.
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
The long intergenic noncoding RNA GAS5 reduces cisplatin-resistance in non-small cell lung cancer through the miR-217/LHPP axis.
LINC01116 promotes proliferation and migration of endometrial stromal cells by targeting FOXP1 via sponging miR-9-5p in endometriosis.
F-Box protein 4 inhibits progression of papillary thyroid cancer.
miR-184 targets TP63 to block idiopathic pulmonary fibrosis by inhibiting proliferation and epithelial-mesenchymal transition of airway epithelial cells.
Pyrvinium pamoate inhibits cell proliferation through ROS-mediated AKT-dependent signaling pathway in colorectal cancer.
CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer.
Role of SIK1 in the transition of acute kidney injury into chronic kidney disease.
Epstein-Barr virus microRNA BART10-3p promotes dedifferentiation and proliferation of nasopharyngeal carcinoma by targeting ALK7.
EPB41L5 promotes EMT through the ERK/p38 MAPK signaling pathway in esophageal squamous cell carcinoma.
MicroRNA-4423-3p inhibits proliferation of fibroblast-like synoviocytes by targeting matrix metalloproteinase 13 in rheumatoid arthritis.
Knockdown hsa_circ_0063526 inhibits endometriosis progression via regulating the miR-141-5p / EMT axis and downregulating estrogen receptors.
A reciprocal feedback of miR-548ac/YB-1/Snail induces EndMT of HUVECs during acidity microenvironment.
USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation.
High throughput proteomic and metabolic profiling identified target correction of metabolic abnormalities as a novel therapeutic approach in head and neck paraganglioma.
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway.
miR-93-5p enhances migration and invasion by targeting RGMB in squamous cell carcinoma of the head and neck.
Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling.
Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling.
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway.
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Emodin inhibiting neutrophil elastase-induced epithelial-mesenchymal transition through Notch1 signalling in alveolar epithelial cells.
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
HOXD9 promote epithelial-mesenchymal transition and metastasis in colorectal carcinoma.
MicroRNA‑500a‑5p inhibits colorectal cancer cell invasion and epithelial‑mesenchymal transition.
miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1.
The LncRNA H19/miR-1-3p/CCL2 axis modulates lipopolysaccharide (LPS) stimulation-induced normal human astrocyte proliferation and activation.
CircATRNL1 promotes epithelial-mesenchymal transition in endometriosis by upregulating Yes-associated protein 1 in vitro.
A combination of Citrus reticulata peel and black tea inhibits migration and invasion of liver cancer via PI3K/AKT and MMPs signaling pathway.
Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells.
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
miR-30e-5p represses angiogenesis and metastasis by directly targeting AEG-1 in squamous cell carcinoma of the head and neck.
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
Antiarthritic Effects of a Root Extract from Harpagophytum procumbens DC: Novel Insights into the Molecular Mechanisms and Possible Bioactive Phytochemicals.
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Ferritinophagic Flux Activation in CT26 Cells Contributed to EMT Inhibition Induced by a Novel Iron Chelator, DpdtpA.
Electrical Stimulation Activates Fibroblasts through the Elevation of Intracellular Free Ca(2+): Potential Mechanism of Pelvic Electrical Stimulation Therapy.
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
PRR14 overexpression promotes cell growth, epithelial to mesenchymal transition and metastasis of colon cancer via the AKT pathway.
VASN promotes YAP/TAZ and EMT pathway in thyroid carcinogenesis in vitro.
Interactome of the Autoimmune Risk Protein ANKRD55.
Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression.
The contrary functions of lncRNA HOTAIR/miR-17-5p/PTEN axis and Shenqifuzheng injection on chemosensitivity of gastric cancer cells.
Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression.
Downregulation of MUTYH contributes to cisplatin‑resistance of esophageal squamous cell carcinoma cells by promoting Twist‑mediated EMT.
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
NAD(+) repletion inhibits the endothelial-to-mesenchymal transition induced by TGF-β in endothelial cells through improving mitochondrial unfolded protein response.
RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.
Resistin-Inhibited Neural Stem Cell-Derived Astrocyte Differentiation Contributes to Permeability Destruction of the Blood-Brain Barrier.
Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.
MiR-876-5p modulates head and neck squamous cell carcinoma metastasis and invasion by targeting vimentin.
Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro.
The molecular landscape of synchronous colorectal cancer reveals genetic heterogeneity.
Inhibition of the receptor for advanced glycation promotes proliferation and repair of human periodontal ligament fibroblasts in response to high glucose via the NF-κB signaling pathway.
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
ECM1 promotes migration and invasion of hepatocellular carcinoma by inducing epithelial-mesenchymal transition.
Carbon monoxide inhibits the nuclear-cytoplasmic translocation of HMGB1 in an in vitro oxidative stress injury model of mouse renal tubular epithelial cells.
Krüppel-Like Factor 4 Overexpression Initiates a Mesenchymal-to-Epithelial Transition and Redifferentiation of Human Pancreatic Cells following Expansion in Long Term Adherent Culture.
Zhu X, Chen H, Xu K, Liu Y, Li H, Sang Y, Zhao Y, Liu X, Wang X, Cui X, Cai B, Shang L, Jing C, Chong W, Li L
Research (Washington, D.C.) 2026;9:1108
Research (Washington, D.C.) 2026;9:1108
A novel Nilotinib derivative N-12 inhibits the proliferation and migration of colon cancer cells through the EMT signaling pathway.
Jiang Z, Ye X, Song M, Qiao Y, Cheng W, Wang D, Zhang X, Li X, Yu X, Wang X, Ji J, Mou Y
Nucleosides, nucleotides & nucleic acids 2026;45(1):64-87
Nucleosides, nucleotides & nucleic acids 2026;45(1):64-87
Graphene Oxide Potentiates Induction Efficiency and Functional Maturation of Induced Mammary Epithelial Cells.
Lei Z, Sun Z, Deng S, Wang G, Liu Q, Huang B, Zhang D
International journal of nanomedicine 2026;21:560553
International journal of nanomedicine 2026;21:560553
LncRNA VCAN-AS1 Sponges miR-374c-3p to Promote Proliferation, Invasion, Migration, and EMT in Thyroid Cancer.
Zhang Y, Sun L, Wu Y, Liu Y, Jiang H, Chen X, Wang L, Wu C
International journal of endocrinology 2026;2026:8809262
International journal of endocrinology 2026;2026:8809262
Stromal cell-derived itaconate promotes endometriosis via macrophage NRF2 and lysosomal pH modulation.
Zhong Z, Wang S, Ren Q, Jiao X, Xu L, Dong X, Li N, Guan H, Chu R, Yuan M, Liu J, Du Y, Wei K, Yan L, Wang G
Redox biology 2026 May;92:104101
Redox biology 2026 May;92:104101
Regulation of EMT and cholangiocarcinoma metastasis by KIN17 through the mTOR signaling pathway.
Yang Y, Luo Q, Huang C, Lin X, Chu LT, Li Q, Tang J, Zeng T
Molecular and cellular biochemistry 2026 May;481(5):2193-2208
Molecular and cellular biochemistry 2026 May;481(5):2193-2208
Fucoidan SPW-05-S2 from Sargassum fusiforme inhibits African swine fever virus replication by blocking PAK2/Talin-1 mediated viral endocytosis and factory formation.
Wan S, Song B, Li S, Cao C, Lu M, Peng G, Ding K, Han K, Yu M
International journal of biological macromolecules 2026 May;360:151801
International journal of biological macromolecules 2026 May;360:151801
Lithocarpus litseifolius leaf extract alleviate hyperuricemia-induced renal injury by regulating uric acid metabolism and inhibiting the AKT/S6K pathway.
Yang W, Gui R, Liu Y, Zou H, Xiao L, Deng G, Wan Z, Yu X, Feng X, Long H, Wang Y, Li D, He X, Xu K
Journal of ethnopharmacology 2026 May 10;362:121362
Journal of ethnopharmacology 2026 May 10;362:121362
β-catenin mutation reprograms ketone body metabolism to drive hepatocellular carcinoma metastasis and resistance to ketogenic therapy via transcriptional activation of OXCT1.
Li H, Qian L, Ji Y, Geng Y, Lu Y, Zhang L, Xu Y, Zong W, Jiang X, Zhou X, Wen J, Liu D, Wang Y, Li Y, Li B, Ma H, Yu D
Cell death & disease 2026 Mar 9;17(1)
Cell death & disease 2026 Mar 9;17(1)
Activation of the PI3K/AKT pathway by EDIL3 induces EMT and promotes tumor progression in clear cell renal cell carcinoma.
Tao L, Xie W, Du Y, Zhang R
Molecular genetics and genomics : MGG 2026 Mar 4;301(1)
Molecular genetics and genomics : MGG 2026 Mar 4;301(1)
A new candidate tumor suppressor tRF-Ser inhibits gastric cancer progression by regulating the CNBP/HSPA8 axis.
Jiao J, Wang G, Liu J, Xiao K, Gao Z, Dong D, Shan K, Cui H, Shang L, Li L, Zhang C
Cell death & disease 2026 Mar 25;17(1)
Cell death & disease 2026 Mar 25;17(1)
USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.
Chen Z, Sun C, Wang Y, Duan X, Ma H, Zhou X, Chen S, Peng P
iScience 2026 Mar 20;29(3):114927
iScience 2026 Mar 20;29(3):114927
Tannic Acid Achieves Rapid Scar-Free Corneal Healing by Chelating Excess Copper to Suppress Aberrant LOX-Mediated Fibrosis.
Cai M, Wang X, Sun S, Yuan Z, Wang Y, Hua X, Yuan X
Investigative ophthalmology & visual science 2026 Mar 2;67(3):13
Investigative ophthalmology & visual science 2026 Mar 2;67(3):13
SPIONs-labeled hUCMSCs for in vitro safety analysis and in vivo tracking in scarred monkey uteri.
Ma H, Wan Y, Shen X, Luo X, Wu S, Lu X, Chen F, Liao W, Deng Q, Chen T, Chu X, Liu Z
Scientific reports 2026 Mar 19;16(1)
Scientific reports 2026 Mar 19;16(1)
Suppression of LTBP1 enhances the sensitivity of bladder cancer to cisplatin.
Li Z, Yu Y, Liu F, Wu Y, Zang Y, Ding Y, Zhang Z
Scientific reports 2026 Mar 13;16(1)
Scientific reports 2026 Mar 13;16(1)
λ-Carrageenan inhibits African swine fever virus infection potentially through its interaction with the viral envelope protein CD2v.
Han K, Sun L, Jin C, Wan S, Cao C, Yue Y, Lu M, Wang X, Zheng Y, Liu H, Guo Y, Tao D, Ruan J, Fu L, Ding K, Xie S, Zhao S, Du K, Yu G, Li G, Chai W, Yan J, Peng G, Yu M
Carbohydrate polymers 2026 Jun 1;381:125142
Carbohydrate polymers 2026 Jun 1;381:125142
Basement membrane-associated gene P3H2 regulates osteosarcoma progression and epithelial-mesenchymal transition through AKT/mTOR signaling axis.
Pan R, Zhang Y, Wang H, Guan J, Chen Z, Xiao L, Ru N, Zhao J, Cheng Y, Feng S, Zheng X
Translational oncology 2026 Jan;63:102569
Translational oncology 2026 Jan;63:102569
CMTM6 promotes synovial proliferation and macrophage polarization by preventing ubiquitination of TAK1 in rheumatoid arthritis.
Luo X, Xu L, Cai J, Ma S, Song H, Yang P, Yang C
Journal of orthopaedic translation 2026 Jan;56:101005
Journal of orthopaedic translation 2026 Jan;56:101005
Narirutin Reprograms Fatty Acid Metabolism and Inhibits Tumorigenesis via Downregulating ADORA3 Expression in Colorectal Cancer.
Wang H, Jiang R, Liu C, Chen F
Journal of gastroenterology and hepatology 2026 Jan;41(1):202-214
Journal of gastroenterology and hepatology 2026 Jan;41(1):202-214
7,8-Dihydroxyflavone Suppresses Experimental Pulmonary Fibrosis by Inhibiting Fibroblast-to-Myofibroblast Transformation and Epithelial-Mesenchymal Transition.
Song YC, Li QL, Liang RJ, Yao JT, Tian Z, Hu YW, Tan TT, Jia DX, Guo DD, Zhu H, Zhao J, Hang PZ
Basic & clinical pharmacology & toxicology 2026 Jan;138(1):e70158
Basic & clinical pharmacology & toxicology 2026 Jan;138(1):e70158
RADA16 and SAAP148 Peptide-Modified Collagen Self-Assembled Hydrogels for Accelerated Healing of Infected Wounds.
Liu Q, Wu J, Bei HP, Chen Y, Zhang Y, Peng X, Chen F, Zhao X, Chen Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e19504
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e19504
CGRP/TSP1 Signaling Dampens Corneal Inflammation and Fibrosis by Targeting A2M During Corneal Stromal Wound Healing.
Ge H, Zhang Y, Guo Q, Li Y, Yang L, Zang X, Xie J, Wang Y, Li Y, Qi X, Wang Y, Zhou Q, Wang X
Investigative ophthalmology & visual science 2026 Jan 5;67(1):10
Investigative ophthalmology & visual science 2026 Jan 5;67(1):10
Glutaminase promotes the malignant progression of esophageal squamous cell carcinoma via TGF-β canonical and noncanonical.
Zhang X, Wang T, Chen Y, Huang M
European journal of medical research 2026 Jan 30;
European journal of medical research 2026 Jan 30;
Improving erectile function in diabetic male mice by rescuing depalmitoylated FBP1 to reduce cavernosal lactate.
Xiao M, Guo W, Zeng R, Wu S, Jin X
Nature communications 2026 Jan 16;17(1):1740
Nature communications 2026 Jan 16;17(1):1740
Discovery of XRF-1021, a 2,4-disubstituted-5-fluoropyrimidine derivative as a homeodomain-interacting protein kinase 2 inhibitor for the treatment of chronic kidney disease.
Hu X, Wang S, Fu S, Zeng J, Wu Y, Gong L, Cao Y, Zhang Y, Han Y, Ouyang H, Xiong Y, He X, Cheng J, Zou S, Chen Z, Tao L, Meng J, Huang L, Yuan Q, Peng Z, Li Q
European journal of medicinal chemistry 2026 Jan 15;302(Pt 2):118353
European journal of medicinal chemistry 2026 Jan 15;302(Pt 2):118353
G3BP2 facilitates abnormal activation of fibroblast-like synoviocytes through p53 signaling pathway in rheumatoid arthritis.
Wu Q, Qin Y, Chen Y, Cheng N, Hu Z, Zheng Y, Wei X, Zhang W, Fang Y, Zhao Y, Zhou R, Hu W, Yao F
International immunopharmacology 2026 Jan 1;168(Pt 2):115961
International immunopharmacology 2026 Jan 1;168(Pt 2):115961
PGK1 Persulfidation Promotes the Proliferation and Metastasis of Breast Cancer.
Luo C, Zhao M, Wang Y, Xu Y, Chen S, Liang W, Yang K, Hu J
Antioxidants & redox signaling 2026 Feb;44(4-6):164-181
Antioxidants & redox signaling 2026 Feb;44(4-6):164-181
Immunohistochemical Evidence of Telocytic Stroma Associated with Tumor Grade and Acinar Heterogeneity in Prostate Cancer.
P Júnior E, Lima MFR, Castro LPF, Ramos PVN, Onofre JCM, Souza RS, Resende V, Belleannée C, Campolina-Silva G, Mamede M
International journal of molecular sciences 2026 Feb 4;27(3)
International journal of molecular sciences 2026 Feb 4;27(3)
Multi-omics analysis reveals RBPJ-mediated regulation of EGF/ACTN2/MYPN/COL21A1 in fibroblast during oviduct functional remodeling of duck.
Niu Y, Zhang Y, Fa C, Qian X, Wang Z, Zhou X, Yu H, Zhao A, Du X
Poultry science 2026 Feb 22;105(6):106688
Poultry science 2026 Feb 22;105(6):106688
Mitochondrial uncoupling sensitizes gastric cancer cells to elesclomol-induced cuproptosis via FDX1/DLAT upregulation.
Lu Y, Li Y, Sun X, Li X, Zhao S, Fang Y, Qiu W, Luo C, Qi W
Free radical biology & medicine 2026 Feb 16;244:284-295
Free radical biology & medicine 2026 Feb 16;244:284-295
EP300 attenuates ferroptosis and stimulates proliferation, migration, and fibrosis of keloid fibroblasts via YY1/GPX4 axis.
Jin J, Wang K, Lu C, Yao C, Xie F
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-16
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-16
Matrix-free cryo-microneedles array patch for 3D hair follicle organoids delivery and rapid hair regeneration.
Wang S, Sun J, Li Y, Zhou Y, Cai Y, Simayijiang Z, Gu Z, Xie Z
Materials today. Bio 2026 Apr;37:102997
Materials today. Bio 2026 Apr;37:102997
Pro-tumourigenic effects of DCAF13 on the progression of colorectal cancer.
Zhang W, Zhang R, Jia M, Lan S, Liu F, Jin Q, Su L, Liu G
Oncology letters 2026 Apr;31(4):145
Oncology letters 2026 Apr;31(4):145
UCHL3 Promotes Triple-Negative Breast Cancer Metastatic Potential Through Enhancing Cell Migration and Invasion.
Xu Q, Yang W, Li C, Yang M, Zhu X, Wang W, Lin Y, Gan Z, He T, Wu X, Li X
Applied biochemistry and biotechnology 2026 Apr 7;
Applied biochemistry and biotechnology 2026 Apr 7;
Extracellular vesicles derived from senescent hepatocytes drive pan-cancer metastasis in aging.
Li H, Zhao R, Wan L, Yuan Y, Ma E, Li Y, Chen Z, Liu B, Song Y, Cao Z, Jiao X, Wang Y, Wu P, Jin H, Li J, Yang X, Huang L, Zhang Y, Yang K, Huo J, Jin H, Zhong H, Min M, Zhang S, Cao Y, Li W, Zhang R, Wei C
Nature aging 2026 Apr 6;
Nature aging 2026 Apr 6;
A conserved re-epithelialization program underlies malignancy in pancreatic ductal adenocarcinoma.
Zhuo M, Li Y, Zhang Y, Yang C, Zou D, Xu W, Han J, Wang S, Deng H, Pan X, Dun R, He R, Shi Y, Han X, Zhang T, Wang W, Dai M, Xu Q, Liu L, Wang W, Liu Y, Liu M, Deng Z, Zhao Y, Wu W, Peng J, Chen M, David CJ
Cancer cell 2026 Apr 30;
Cancer cell 2026 Apr 30;
IL-5 promotes airway remodeling in asthma by mediating epithelial-mesenchymal transition via the AKT/NLRP3 pathway.
Zhao L, Lin Y, Dou M, Su H, Han L, Wu J, Lu Y, Bao W, Zhang M
International immunopharmacology 2026 Apr 15;175:116422
International immunopharmacology 2026 Apr 15;175:116422
CRYM suppresses glioblastoma progression by inhibiting the TGFβ1/Smad-EMT signaling pathway.
Xu Y, Zhao P, Yao Z, Shen T, Ding S, Hua Y, Zhang F, Jiang X, Di G, Xia H
Journal of neuro-oncology 2026 Apr 13;177(2)
Journal of neuro-oncology 2026 Apr 13;177(2)
ETV1 transcriptional manipulation of KIFC1 regulates the progression of pancreatic cancer.
Hu F, Bai Z, Wang Y, Tang H, Zhou J
Oncology research 2025;33(7):1723-1737
Oncology research 2025;33(7):1723-1737
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
Peng J, Xue Y, Cai Z, Li Z, Han K, Lin X, Li Y, Zhuo Y
Oncology research 2025;33(10):3127-3154
Oncology research 2025;33(10):3127-3154
Inhibition of Mettl3 alleviates low-dose cisplatin-induced renal fibrosis and enhances the chemotherapeutic efficacy in mouse models of cancer.
Xie Y, Li H, Pan J, Li Y, Zhang D
International journal of biological sciences 2025;21(10):4293-4311
International journal of biological sciences 2025;21(10):4293-4311
Abnormally Activated MNX1 Promotes Tumor Growth and Osimertinib Resistance and Predicts Survival in EGFR-Mutant Lung Adenocarcinoma.
Gu W, Gan J, Liu P, Lai J, Liu C, Zhang G, Shi C, Jiang Q, Qiu F
Drug design, development and therapy 2025;19:11411-11431
Drug design, development and therapy 2025;19:11411-11431
Identification of Key Genes Involved in the Occurrence and Development of Endometrial Cancer.
Huang M, Zhu Q, Tan K, Chen X
International journal of women's health 2025;17:4311-4321
International journal of women's health 2025;17:4311-4321
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Yan J, Zhao W, Wang H, Zhou L, Li X, Wang G
Hepatic medicine : evidence and research 2025;17:141-159
Hepatic medicine : evidence and research 2025;17:141-159
System Analysis Identifies MYBL2 As a Novel Oncogene Target for Metastatic Prostate Cancer.
Huang R, Li J, Zhu J, Deng W, Wang Z, Xiang S
Journal of Cancer 2025;16(6):1768-1781
Journal of Cancer 2025;16(6):1768-1781
Identification of CAF signature genes and construction of CAF-based risk signature in hepatocellular carcinoma by multi-omics analysis.
Qian W, Wu K, Shen Z, Ni B, Zheng H, Liu Y, Guo M
Frontiers in immunology 2025;16:1690174
Frontiers in immunology 2025;16:1690174
CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.
Sun K, Wen S, Guo SJ, Pan QH, Wang KR
Frontiers in immunology 2025;16:1682724
Frontiers in immunology 2025;16:1682724
MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.
Sun K, Wen S, Guo SJ, Pan QH, Wang KR
Frontiers in immunology 2025;16:1681887
Frontiers in immunology 2025;16:1681887
MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma.
Qi R, Fang C, Liu P, Gu W, Shi C, Zhang G, Qiu F
Frontiers in genetics 2025;16:1615018
Frontiers in genetics 2025;16:1615018
Enhancing pancreatic cancer treatment: the role of H101 oncolytic virus in irreversible electroporation.
Xi P, Zeng D, Chen M, Jiang L, Zhang Y, Qin D, Yao Z, He C
Frontiers in immunology 2025;16:1546242
Frontiers in immunology 2025;16:1546242
Screening and identification of protein 29 of Echinococcus granulosus interacting molecules.
Shang Z, Qiao F, Li Y, Ma X, Wang M, Yang W, He T, Ma H, Wang Y
Frontiers in cellular and infection microbiology 2025;15:1560436
Frontiers in cellular and infection microbiology 2025;15:1560436
Ciprofol exerts anti-tumour effects in hepatocellular carcinoma through the Raf-MEK-ERK signalling pathway.
Chen Y, Shi P, Zhou S, Yu K, Wang Y, Yao F, Zhang R, Liu X, Fang C, Tie X, Li J, Xu J, Xu J, Pan X
Translational gastroenterology and hepatology 2025;10:52
Translational gastroenterology and hepatology 2025;10:52
The Down-Regulation of Lactoferrin Expression Induced by Cigarette Smoke can Induce Ferroptosis in COPD.
Wang Y, Xu W, Ren K, Yang J, Min L
Lung 2025 Sep 23;203(1):96
Lung 2025 Sep 23;203(1):96
Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer.
Xiong L, Tang 唐磊 L, Zhao W, Wang R, Cheng C, Wang D, Xu Y, Tang 汤磊 L, Fan Y
Journal of advanced research 2025 Sep 22;
Journal of advanced research 2025 Sep 22;
Dietary addition of magnesium hydride nanoparticles: a breakthrough in combating high-fat diet-induced chronic kidney disease.
Lu H, Chen W, Ying Y, Gu D, Li R, Li X, Cheng J, Sun X, Zhang Y, Liu W, Shen H
Medical gas research 2025 Sep 1;15(3):374-382
Medical gas research 2025 Sep 1;15(3):374-382
TKT regulates the pentose phosphate pathway via RBKS to promote epithelial-mesenchymal transition during AML progression.
Li F, Liu J, Geng Y, Liu L, Li J, Pu L, Hu Z, Yang Y
Journal of bioenergetics and biomembranes 2025 Oct;57(4-5):289-302
Journal of bioenergetics and biomembranes 2025 Oct;57(4-5):289-302
Titanium surface modified with nanostructure mimicking the surface of natural cementum up-regulated epithelial expression of integrin β4 and enhanced the attachment of the transmucosal gingiva.
Deng Z, Yu L, Sun Y, Kuang Y, Zhou Z, Chen M, Li X
Dental materials : official publication of the Academy of Dental Materials 2025 Oct;41(10):1201-1212
Dental materials : official publication of the Academy of Dental Materials 2025 Oct;41(10):1201-1212
Endothelial HMGB1-AIM2 axis worsens myocardial ischemia-reperfusion injury by regulating endothelial pyroptosis.
Chen R, Duan J, Zhou Y, Cao M, Su Y, Jiang D, Tao A, Yuan W, Dai Z
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2466-2479
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2466-2479
Rottlerin inhibits PKCδ to attenuate pulmonary fibrosis by suppressing NLRC4/ASC-mediated pyroptosis.
Wang Y, Zhang T, Gou X, Yuan W, He S, Zhang S, Chen Z, Xu G, Wu D, Xu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157154
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157154
Geniposide alleviates kidney fibrosis by targeting STAT3-HK2-mediated glycolysis.
Shi R, Liu MQ, Xiao JP, Zhu YK, Zhu JX, Zhao WM, Wang ZJ, Zhu YY, Li XL, Wang XR, Wang RF, Wang DG
BMC complementary medicine and therapies 2025 Oct 9;25(1):365
BMC complementary medicine and therapies 2025 Oct 9;25(1):365
KAT2A-H3K79succ-Mediated SH2B3 Upregulation Promotes TNBC Metastasis Through Diminishing the Ubiquitin-Dependent Degradation of Vimentin.
Shi X, Hao R, Yang Z, Wang X, Lu Y, Wang X, Ji H, Ma S, Liu X, Hu J, Qi Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71140
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71140
FUT8 promotes HDM-induced glycolysis, epithelial-mesenchymal transition and inflammation in bronchial epithelial cells by inducing N-glycosylation modification of GLUT1.
Huang W, Yuan X, Lu J, Zhang S, Sun Y, Hang Y, Shen Y, Chen M, Li J, Huang J, Zhang W, Li L
Biochemical and biophysical research communications 2025 Oct 30;786:152721
Biochemical and biophysical research communications 2025 Oct 30;786:152721
Pan-cancer analysis of role of LOXL4 and experiment validation in osteosarcoma.
Chen W, Xie F, Lv J, Huang D, Zhong R, Wen Z, Sun J, Zheng S, Liu W, Zhong H, Huang S
Discover oncology 2025 Oct 21;16(1):1926
Discover oncology 2025 Oct 21;16(1):1926
Hsa_circRNA_0101125 Promotes Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma via miR-143-3p/ZNF148 Axis.
Chen H, Xue S, Cao S, Zhang J, Wei Y, Chen C, Xu G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 15;39(19):e71031
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 15;39(19):e71031
Liver metastasis or peritoneal metastasis: single-cell RNA sequencing reveals the organotropism in colorectal cancer is driven by distinct partial-EMT processes.
Yu C, Lu W, Wu J, Fang X, Wang X, Zhang G, Chen S, Mei Y, Chen H, Ye F, Yang H, Qian Y, Kong X, Zhang P, Wang J, Guo G, Ding K
Cancer letters 2025 Oct 1;629:217880
Cancer letters 2025 Oct 1;629:217880
Mitochondrial dysfunction-associated cellular senescence is partially involved in bleomycin-induced pulmonary fibrosis in mice.
Yao YX, Lu X, Li Z, Liao HY, Liu ZB, Zhao H, Wang H, Xu DX, Tan ZX
Toxicology and applied pharmacology 2025 Nov;504:117524
Toxicology and applied pharmacology 2025 Nov;504:117524
Identification and validation of BCL11A as a neural and immune vulnerability factor in pancreatic adenocarcinoma.
Chen A, Wang J, Yang J, Wang Y, Wu C, Yang H, Fan Y, Gao Q, Hu Y, Li X, Zou X
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):167988
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):167988
Kindlin-1 promotes mitophagy by inhibiting PINK1 degradation to enhance hepatocellular carcinoma progression and modulates sensitivity to donafenib.
Ma H, Ou G, Wu B, Ding H, Zhang Y, Xia F, Shen Z, Zhao K, Chen C, Wu L, Lei J, Xu Y, Zhao X, Cao K, Li H
Cellular signalling 2025 Nov;135:112032
Cellular signalling 2025 Nov;135:112032
The E3 ubiquitin ligase TRIM31 enhances the progression of esophageal cancer through the ubiquitination of BBOX1.
Ge L, Sun M, Xu D, Sun G
Cellular signalling 2025 Nov;135:111975
Cellular signalling 2025 Nov;135:111975
TGF-β1 mediates epithelial-mesenchymal transition in interstitial cystitis through the regulation of ROCK.
Long X, Yu B, Chen M, Zhang Q, Wang Y, Huang Y, Wu J, Cen P, Lan H, Long J, Zhang Z, Zhong J, Duan X, Yu Q, Gu D
European journal of pharmacology 2025 Nov 5;1006:178184
European journal of pharmacology 2025 Nov 5;1006:178184
Neutrophil extracellular traps regulate LDHA expression to promote colorectal cancer liver metastasis.
Li N, Yang S, Hu C, Zheng J, Yang H, Jiang T, Li X, Han Q, Zhang X, Yang Y, Khan S, Sun B
Journal of translational medicine 2025 Nov 3;23(1):1208
Journal of translational medicine 2025 Nov 3;23(1):1208
MiR-106b-5p promotes gastric cancer progression by directly targeting the tumor suppressor RBL2.
Luo C, Wang C, Chang T, Niu Y, Zhang H, Li F, Zhang B
Scientific reports 2025 Nov 29;16(1):985
Scientific reports 2025 Nov 29;16(1):985
Scutellarin triggers ferroptosis in ovarian cancer cells via inhibiting AKT/mTOR and JAK2/STAT3 pathways.
Wang S, Zhang M, Tang C, Xia T, Gao L, Chen Q, Gao F, Ye W, Wang H, Jin M, Jiang X, Gao L, Xu Z, Zhu R, Yan X, Zhu J, Ye Z, Yan J, Zhang G, Wang W
Medical oncology (Northwood, London, England) 2025 Nov 25;43(1):24
Medical oncology (Northwood, London, England) 2025 Nov 25;43(1):24
SGK1 inhibits oxidative injury and extracellular matrix degradation by activating the GSK-3β (Ser9)/Fyn/NRF2 pathway in pelvic organ prolapse.
Yan Y, Peng J, He W, Chen Y, Ye W, Yin Z, Cao Y
Life sciences 2025 Nov 1;380:123939
Life sciences 2025 Nov 1;380:123939
Lipocalin 2 Facilitates the Initial Compromise of the Blood-Brain Barrier Integrity in Chronic Cerebral Hypoperfusion.
Nie Q, Zhang L, Gu Z, Li Y, Bi X
CNS neuroscience & therapeutics 2025 May;31(5):e70438
CNS neuroscience & therapeutics 2025 May;31(5):e70438
METTL3-mediated m6A modification of PAK6 drives cervical cancer progression through activating MAPK14.
Zhu ZM, Huo FC, Shi C, Li MT, Zhou Y, Zhang LS, Pei DS
International journal of biological macromolecules 2025 May;309(Pt 2):142880
International journal of biological macromolecules 2025 May;309(Pt 2):142880
CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.
Wang J, Du J, Song Y, Tan X, Wu J, Wang T, Shi Y, Xu X, Yu Z, Song B
Cell death & disease 2025 May 9;16(1):371
Cell death & disease 2025 May 9;16(1):371
Saliva-derived extracellular vesicles: a promising therapeutic approach for salivary gland fibrosis.
Peng B, Guo X, Kang J, Pan S, Wei L, Wang L, Li B, Han G, Cheng Y
Journal of translational medicine 2025 May 27;23(1):593
Journal of translational medicine 2025 May 27;23(1):593
Piezo1 regulates actin cytoskeleton remodeling to drive EMT in cervical cancer through the RhoA/ROCK1/PIP2 signaling pathway.
Deng J, Li Y, Zhang L, Liao W, Liu T, Shen F
Discover oncology 2025 May 16;16(1):787
Discover oncology 2025 May 16;16(1):787
Annexin A2 Contributes to Release of Extracellular Vimentin in Response to Inflammation.
Yuan Z, Ostrowska-Podhorodecka Z, Cox T, Norouzi M, Wang Y, Robaszkiewicz K, Siatkowska M, Xia K, Ali A, Abovsky M, Jurisica I, Smith P, McCulloch CA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 15;39(9):e70621
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 15;39(9):e70621
SOX4 as a Key Oncogene Driving Tumor Invasion in Retinoblastoma.
Nie J, Tang J, Zhang Z, Sun H, Wang X, Wang L, Wang M, Huang W, Gao Y, Li J, Cheng C, Su S, Chen S, Ai S, Mao Y, Zhang P, Liu Y, Lu R
Investigative ophthalmology & visual science 2025 May 1;66(5):24
Investigative ophthalmology & visual science 2025 May 1;66(5):24
UBE2C mediates follicular thyroid carcinoma invasion and metastasis via K29-Specific vimentin ubiquitination.
Xu L, Dai B, Zhang L, Chen W, Rong S, Chen J, Song M, Lan Z, Liu Y, Wang L, Li J, Chen J, Wu Z
Cancer letters 2025 May 1;617:217624
Cancer letters 2025 May 1;617:217624
Berberine Inhibits Migration and Apoptosis of Rat Podocytes in Diabetic Nephropathy via the Novel lncRNA LOC102549726 Related Pathway.
Wang C, Wu H, Xie Y, Wang J, Huang L, Ni X, Deng S, Zhang Y, Chen X, Zhang H, Yuan S, Tang L
Phytotherapy research : PTR 2025 Mar;39(3):1615-1631
Phytotherapy research : PTR 2025 Mar;39(3):1615-1631
The role of fibromodulin in myocardial fibrosis in a diabetic cardiomyopathy rat model.
Dai X, Yang F, Chen D, Yang L, Dong Z, Chen C, Xiao J
FEBS open bio 2025 Mar;15(3):436-446
FEBS open bio 2025 Mar;15(3):436-446
Enhanced Vascular Smooth Muscle Cell and Extracellular Matrix Repair Using a Metal-Organic Framework-Based Co-Delivery System for Abdominal Aortic Aneurysm Therapy.
Lei J, Dong X, Huang Y, Wu Z, Peng Z, Li B, Wang R, Pan Y, Zheng X, Zhao Z, Lu X
Advanced healthcare materials 2025 Mar;14(6):e2402937
Advanced healthcare materials 2025 Mar;14(6):e2402937
The roles of HOXB9 and MMP12 in proliferation, migration, and invasion of human laryngeal cancer cells LCC and TU212.
Sun C, Deng H, Wang Q, Long Y, Li T, Song C, Han C
Biochemical and biophysical research communications 2025 Mar 8;752:151391
Biochemical and biophysical research communications 2025 Mar 8;752:151391
NEAT1 promotes the perineural invasion of pancreatic cancer via the E2F1/GDNF axis.
Gu J, Wang Q, Mo J, Qin T, Qian W, Duan W, Han L, Wang Z, Ma Q, Ma J
Cancer letters 2025 Mar 31;613:217497
Cancer letters 2025 Mar 31;613:217497
Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis.
Lu Q, Liu J, Xiong Y, Jian J, Wang J, Chen Z, Wan S, Liu X, Wang L
Scientific reports 2025 Mar 28;15(1):10695
Scientific reports 2025 Mar 28;15(1):10695
Isoliquiritigenin attenuates tumor progression and PD-L1 expression by inhibiting the phosphorylation of STAT3 in melanoma.
Zeng H, Guo A, Liu Z, Xiang S, Zheng F
Medical oncology (Northwood, London, England) 2025 Mar 19;42(4):118
Medical oncology (Northwood, London, England) 2025 Mar 19;42(4):118
Astilbin Alleviates Radiation-Induced Pulmonary Fibrosis via circPRKCE Targeting the TGF-β/Smad7 Pathway to Inhibit Epithelial-Mesenchymal Transition.
Shi Z, Liu J, Qin J, Liang X, Ou X, Zhang T, Yan X, Hu Q, Huang W, Hu K
Biomedicines 2025 Mar 11;13(3)
Biomedicines 2025 Mar 11;13(3)
Metformin Attenuates Partial Epithelial-Mesenchymal Transition in Salivary Gland Inflammation via PI3K/Akt/GSK3β/Snail Signaling Axis.
Peng B, Wang L, Pan S, Kang J, Wei L, Li B, Cheng Y
Inflammation 2025 Jun;48(3):1525-1537
Inflammation 2025 Jun;48(3):1525-1537
Glycated ECM Derived Carbon Dots Inhibit Tumor Vasculogenic Mimicry by Disrupting RAGE Nuclear Translocation and Its Interaction With HMGB1.
Zheng S, Zhang X, Yang F, Chang Z, Han J, Zhang H, Liu H, Sun T
Advanced materials (Deerfield Beach, Fla.) 2025 Jun;37(24):e2419540
Advanced materials (Deerfield Beach, Fla.) 2025 Jun;37(24):e2419540
Apelin-13 Protects Against Airway Inflammation, Oxidative Stress, and Epithelial-Mesenchymal Transition in a Chronic Asthma Model.
Sun H, Wang A, Shi N
Chemical biology & drug design 2025 Jun;105(6):e70142
Chemical biology & drug design 2025 Jun;105(6):e70142
Omentin-1 attenuates atrial fibrillation via Src/PI3K/Akt signaling-mediated anti-fibrotic effects in cardiac fibroblasts.
Li TL, Zhu NN, Zhao MX, Sun J, Yin Z, Xie P, Huang JH, Guo JP, Yuan HT, Li SX, Zhao-Liang S
European journal of pharmacology 2025 Jun 5;996:177588
European journal of pharmacology 2025 Jun 5;996:177588
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Yu W, Gui S, Peng L, Luo H, Xie J, Xiao J, Yilamu Y, Sun Y, Cai S, Cheng Z, Tao Z
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Ancestry-linked stromal variations impact breast epithelial cell invasion.
Schmidtmann MG, Elliott V, Clancy JW, Schafer ZT, Nakshatri H, D'Souza-Schorey C
iScience 2025 Jun 20;28(6):112686
iScience 2025 Jun 20;28(6):112686
The upregulation of TNKS1 drives the phenotypic switching of vascular smooth muscle cells in aortic dissection through the activation of ferroptosis.
Xu X, Lin W, Liu T, Yuan C, Yan Y, Diao Y, Xiong J, Shao Y, Ni B
International immunopharmacology 2025 Jun 17;158:114722
International immunopharmacology 2025 Jun 17;158:114722
METTL3 Modulates Radiation-Induced Cardiac Fibrosis via the Akt/mTOR Pathway.
Qiao S, Tang C, Zhu J, Feng Y, Xiang L, Zhu J, Gu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70666
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70666
Novel insights into human CRISP2: localization in reproductive tissues and sperm, and molecular characterization†.
Masai T, Delnatte A, Dendievel M, Nonclercq D, Frau A, Simon JF, Arcolia V, Wattiez R, Leroy B, Cuasnicu PS, Lybaert P, Hennebert E
Biology of reproduction 2025 Jun 15;112(6):1167-1184
Biology of reproduction 2025 Jun 15;112(6):1167-1184
Comprehensive multi-omics analysis of histone acetylation modulators identifies ASH1L as a novel aggressive marker for osteosarcoma.
Ni C, Sun Q, Yin H
Discover oncology 2025 Jun 12;16(1):1070
Discover oncology 2025 Jun 12;16(1):1070
Role of the USP7/FOXO3A axis in environmentally relevant doses of arsenic-induced lung carcinogenesis: Insights from bioinformatics analysis and model of human epithelial cell malignant transformation.
Chen X, Wang Y, Liu Z, He Y, Gao H, Guan X, Chen L, Chen S, Xing X, Chen W, Li D, Wang Q
Ecotoxicology and environmental safety 2025 Jun 1;297:118224
Ecotoxicology and environmental safety 2025 Jun 1;297:118224
Increased SUMO-activating enzyme subunit 1 promotes glycolysis and fibrotic phenotype of diabetic nephropathy.
Wusiman R, Haimiti S, Abuduaini H, Yang M, Wang Y, Gu M, Sailike A, Gao L
Biochemical pharmacology 2025 Jul;237:116920
Biochemical pharmacology 2025 Jul;237:116920
Neoadjuvant Chemotherapy With Cisplatin Up-Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14-Mediated EMT Activation.
Huang Z, Jiang Q, Zhang Q, Lu N, Rui X, Chen R, Wang Y, Wang Y, Xu X, Huang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501149
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501149
P300-dependent acetylation of the FOXQ1 complex activates super-enhancers to promote colorectal cancer proliferation and metastasis.
Yang WD, Zhang ZH, Zhao MY, Shao K, Ma YF, Shen Q, Lu MR, Shao ZY, Xu JY, Cao MH, Meng S, Chu SF, Yong HM, Ding J, Bai J
Communications biology 2025 Jul 7;8(1):1016
Communications biology 2025 Jul 7;8(1):1016
Systematic identification of SNCA as a key gene in ischemic cardiomyopathy via integrated weighted gene co-expression network analysis and experimental validation.
Zhu Y, Cao B, Huang K, Liu J
Biochemical and biophysical research communications 2025 Jul 30;772:152063
Biochemical and biophysical research communications 2025 Jul 30;772:152063
GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2.
Hu Q, Chen Q, Yang W, Ren A, Tan J, Huang T
Cell communication and signaling : CCS 2025 Jul 25;23(1):355
Cell communication and signaling : CCS 2025 Jul 25;23(1):355
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Tu Y, Xiong Y, Liu O, Peng Y
Experimental cell research 2025 Jul 15;450(2):114658
Experimental cell research 2025 Jul 15;450(2):114658
Elevated SGO2 expression in lung adenocarcinoma promotes migration and invasion via MAD2 and correlates with poor prognosis.
Sun M, Zhou W, Wei G, Lv M, Sun Y, Zhao H, Zhu C
Scientific reports 2025 Jul 15;15(1):25642
Scientific reports 2025 Jul 15;15(1):25642
CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism.
Liu M, Gong Y, Cai H, Hua R, Li H, Wang Z, Zhou Y, Ma Y, Quan S
Journal of translational medicine 2025 Jul 10;23(1):763
Journal of translational medicine 2025 Jul 10;23(1):763
The molecular subtype based on cell cycle-related gene signature predicts the prognosis and chemotherapy and immunotherapy response in gastric cancer.
Su R, Chen J, Dai C, Yin S, Chen H, Sun X, Fang Z, Zhang C, Chen J, Gu L
Scientific reports 2025 Jul 1;15(1):20858
Scientific reports 2025 Jul 1;15(1):20858
ERβ-regulated circATP2B1/miR-204-3p/TWIST1 positive feedback loop facilitates epithelial to mesenchymal transition in clear cell renal cell carcinoma.
Wang H, Gao Y, Guo F, Zhou P, Ma Z, Chi K, Ye J, Sun H, He X, Shi B, Wang Y, Han Z
Translational oncology 2025 Jan;51:102213
Translational oncology 2025 Jan;51:102213
Proteomics analysis revealed the therapeutic role of adipose-derived mesenchymal stem cells on radiation-induced colorectal fibrosis in rats.
Thandar M, Zhang L, Yang X, Chi P, Li Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jan;182:117763
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jan;182:117763
NAP1L5 promotes epithelial-mesenchymal transition by regulating PEG10 expression in acute myeloid leukaemia.
Wu H, Luo H, Wang M, Du Y, Li J
Leukemia research 2025 Jan;148:107623
Leukemia research 2025 Jan;148:107623
Sang-Bai-Pi extract and its constituent regiafuran C ameliorate renal fibrosis through TGF-β/Smad and Wnt/β-catenin signaling pathways.
Wei QH, Pan YB, Tian LL, Wang YS, Wang JY, Liu X, Zhang H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156351
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156351
Mechanistic insights into the treatment of pulmonary fibrosis with bioactive components from traditional chinese medicine via matrix stiffness-mediated EMT.
Li K, Liu H, Li M, Sun M, Peng X, Wu Y, Tian Y, Liu X, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156266
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156266
Xihuang pill suppresses breast cancer malignancy by inhibiting TGF-β signaling and acquires chemotherapy benefits.
Hong W, Tang H, Wang D, Qian D, Xu Y, Zheng Y, Li S, Zheng Q, Meng X, Liu X
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):119000
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):119000
3D printed biomimetic bilayer limbal implants for regeneration of the corneal structure in limbal stem cell deficiency.
Wang L, Nie X, Wei Y, Chen Q, Sun Y, Zhao X, Xu X, Liu W, Liang Q
Acta biomaterialia 2025 Jan 24;193:157-170
Acta biomaterialia 2025 Jan 24;193:157-170
Pirfenidone alleviates interstitial lung disease in mice by inhibiting neutrophil extracellular trap formation and NLRP3 inflammasome activation.
Su Q, Feng Y, Guo J, Cui X, Zhu J, Yang J, Zhang S
Clinical and experimental immunology 2025 Jan 21;219(1)
Clinical and experimental immunology 2025 Jan 21;219(1)
Inhibition of Myocardin-related Transcription Factor A Ameliorates Pathological Remodeling of the Pressure-loaded Right Ventricle.
Rzepka MF, Raschzok S, Lee XA, Yazaki K, Dauz J, Sun M, Meister T, Nghiem L, Kabir G, Desjardins JF, Kuebler WM, Kapus A, Connelly KA, Friedberg MK
American journal of respiratory cell and molecular biology 2025 Feb;72(2):158-168
American journal of respiratory cell and molecular biology 2025 Feb;72(2):158-168
Regulation of pancreatic cancer cells by suppressing KIN17 through the PI3K/AKT/mTOR signaling pathway.
Li Q, Yang Y, Lin X, Chu LT, Chen H, Chen L, Tang J, Zeng T
Oncology reports 2025 Feb;53(2)
Oncology reports 2025 Feb;53(2)
CB-MNCs@ CS/HEC/GP promote wound healing in aged murine pressure ulcer model.
Yang ZC, Lin H, Liu GJ, Pan H, Zhu JL, Zhang XH, Gao F, Wang Z, Wang ZH
Stem cell research & therapy 2025 Feb 7;16(1):52
Stem cell research & therapy 2025 Feb 7;16(1):52
Ultrasound-guided renal subcapsular transplantation of mesenchymal stem cells for treatment of acute kidney injury in a minipig model: safety and efficacy evaluation.
Xiao T, Chen Y, Jiang B, Huang M, Liang Y, Xu Y, Zheng X, Wang W, Chen X, Cai G
Stem cell research & therapy 2025 Feb 28;16(1):102
Stem cell research & therapy 2025 Feb 28;16(1):102
The inhibition of ZC3H13 attenuates G2/M arrest and apoptosis by alleviating NABP1 m6A modification in cisplatin-induced acute kidney injury.
Sheng Q, Yu Q, Lu S, Yang M, Fan X, Su H, Kong Z, Gao Y, Wang R, Lv Z
Cellular and molecular life sciences : CMLS 2025 Feb 22;82(1):86
Cellular and molecular life sciences : CMLS 2025 Feb 22;82(1):86
Harnessing 2D and 3D human endometrial cell culture models to investigate SARS-CoV-2 infection in early pregnancy.
Liu A, Ruetalo N, Raja Xavier JP, Lankapalli AK, Admard J, Camarena-Sainz M, Brucker SY, Singh Y, Schindler M, Salker MS
Clinical science (London, England : 1979) 2025 Feb 19;139(4):287-307
Clinical science (London, England : 1979) 2025 Feb 19;139(4):287-307
A novel piperine derivative HJJ_3_5 inhibits colorectal cancer progression by modulating EMT signaling pathways.
Cheng W, Liu S, He J, Li H, Liu X, Hu Z, Wang X, Wu Z, Xu G, Liu W, Liu B
Biochemical and biophysical research communications 2025 Feb 16;749:151323
Biochemical and biophysical research communications 2025 Feb 16;749:151323
B7-H3 enhances the malignant phenotype of colorectal cancer by activating the Wnt/β-catenin pathway mediated by CYP1B1.
Liu X, Ding J, Zong Q, Mao Y
Tissue & cell 2025 Dec;97:103066
Tissue & cell 2025 Dec;97:103066
TM4SF1 as a Prognostic Biomarker and Therapeutic Target in Cervical Cancer.
Deng JX, Zhang LY, Ouyang ZQ, Guo T, Shen FJ, Zheng HY
Current medical science 2025 Dec;45(6):1367-1381
Current medical science 2025 Dec;45(6):1367-1381
Adipose-derived mesenchymal stem cell exosomes protect keratinocytes from high-glucose injury by modulating KEAP1/NRF2/HO-1 axis.
Yuan Y, Song S, Xiao Y, Feng R, Li M, Zhang H, Luo L, Wang K, Wang P, Wei L, Zhang Y, Zhang B, Jiang S, Shen K, Guan H, Hu D
Cellular signalling 2025 Dec;136:112172
Cellular signalling 2025 Dec;136:112172
Cinobufagin Directly Targets PDE4D to Disrupt Fibroblast-Dendritic Cell Crosstalk in Atopic Dermatitis.
Li S, Xu D, Zhang C, Xiao C, Yu M, Wang J, Wu W, Lv X, Yuan D, Zhang L, Hong M, Zhou J, Sun Y, Ma H, Zhu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e01670
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e01670
Exosome-derived Menin from cancer-associated fibroblasts promotes gastric cancer progression by activating the HSPA6/JNK/JunD pathway and inducing EMT.
Wang SH, Jiang JX, Zheng KT, Zhang SJ, Chen TD, Wang Z
Journal of translational medicine 2025 Dec 6;24(1):274
Journal of translational medicine 2025 Dec 6;24(1):274
PLS3 Is a Prognostic Biomarker and Correlates with Immune Infiltrates in Head and Neck Squamous Cell Carcinoma.
Wang Y, Chen K, Tian G, Hou C, Huang Y, Song F, Zhang M, Hou J
Cancers 2025 Dec 4;17(23)
Cancers 2025 Dec 4;17(23)
Alpha-1 Antitrypsin Mediates Spontaneous Resolution of Acute Gouty Inflammation Via Inhibiting Caspase 3/GSDME-dependent Macrophage Pyroptosis.
Li X, Liu L, Tong S, Wang F, Zhu L, Cheng Q, Zhang P, Chen M, Xie Y, Wang L, Yu H, Wu H
Inflammation 2025 Dec 20;49(1):12
Inflammation 2025 Dec 20;49(1):12
Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells.
Sun Y, Wang J, Gu D, Lou H, Sun J, Cui Z, Kang W
Cell death & disease 2025 Dec 18;17(1):101
Cell death & disease 2025 Dec 18;17(1):101
HIF-1α mediates mitochondrial damage by down-regulating ALKBH7 expression to promote the aberrant activation of FLS in rheumatoid arthritis.
Wang H, Zhao YC, Xu L, Zhang TJ, Liu LH, Zhou MQ, Zhang H, Yang YN, Pan P, Jin L, Zhang ZW, Zhang XZ, Zhang LL
Acta pharmacologica Sinica 2025 Aug;46(8):2225-2236
Acta pharmacologica Sinica 2025 Aug;46(8):2225-2236
Elastin-like polypeptide and triclosan-modified PCL membrane provides aseptic protection in tissue regeneration.
Peng X, Wang Y, Liu S, Zhang J, Liu L, Liu Q, Li X, Chen F, Chen Z
Materials today. Bio 2025 Aug;33:101968
Materials today. Bio 2025 Aug;33:101968
Thermosensitive hydrogel composite with si-Cx43 nanoparticles and anti-VEGF agent for synergistic treatment of diabetic retinopathy.
Wen L, Gan M, Xiong S, Dai L, Chen W, Shi W
Materials today. Bio 2025 Aug;33:101917
Materials today. Bio 2025 Aug;33:101917
Newcastle disease virus promotes spreading infection through vimentin-dependent tight junction injury mediated by MLC/p-MLC activation.
Lu X, Zhou Q, Wang M, Li M, Yang W, Liu K, Gao R, Liao T, Chen Y, Hu J, Gu M, Hu S, Jiao X, Wang X, Liu X, Ding C, Liu X
PLoS pathogens 2025 Aug;21(8):e1013458
PLoS pathogens 2025 Aug;21(8):e1013458
Circ847 upregulation via CAFs suppresses salivary adenoid cystic carcinoma progression through VIM-EMT.
Liang Y, Zhou Y, Xu T, Wang Y, Xu X, Chen R, Jiang Q, Lu N, Zhao L, Huang Z, Huang Z
Cellular signalling 2025 Aug;132:111806
Cellular signalling 2025 Aug;132:111806
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer.
Xie X, Zhao Y, Liu J, Li H, Zhu X, Liu Y, Sang Y, Xu K, Du F, Ren H, Cui X, Cai B, Chen H, Wu N, Hou G, Jing C, Chong W, Li L, Shang L
Cell death & disease 2025 Aug 7;16(1):596
Cell death & disease 2025 Aug 7;16(1):596
DDX18 promotes growth and metastasis of hepatocellular carcinoma via activating EMT and MAPK signaling.
Xu X, Yu X, Zhang N, Wang F, Chen Z
Journal of gastrointestinal oncology 2025 Aug 30;16(4):1622-1634
Journal of gastrointestinal oncology 2025 Aug 30;16(4):1622-1634
Inhibition of macrophage extracellular traps by Metrnl/IL-41 suppresses airway remodeling in asthma.
Feng K, Cen J, He C, Zou X, Yang H, Lin Y, Li H, Zhang T
Biochemical pharmacology 2025 Aug 28;242(Pt 1):117288
Biochemical pharmacology 2025 Aug 28;242(Pt 1):117288
Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma.
Huang H, Peng W, Zhou Q, Zhao Y, Liu L, Cui H, Liang J, Cao M, Chen W, Wang R, Chen S, Xiong S, Cheng B, Bai S
Cell communication and signaling : CCS 2025 Aug 25;23(1):379
Cell communication and signaling : CCS 2025 Aug 25;23(1):379
POC1A induces epithelial-mesenchymal transition to promote growth and metastasis through the STAT3 signaling pathway in triple-negative breast cancer.
Qian Y, Che Y, Li S, Zhang X, Li Q, Zhu Y, Wang L, Yin X
Molecular medicine (Cambridge, Mass.) 2025 Aug 19;31(1):280
Molecular medicine (Cambridge, Mass.) 2025 Aug 19;31(1):280
SOX17 Prevents Endothelial-Mesenchymal Transition of Pulmonary Arterial Endothelial Cells in Pulmonary Hypertension through Mediating TGF-β/Smad2/3 Signaling.
Zou X, Yuan M, Zhou W, Cai A, Cheng Y, Zhan Z, Zhang Y, Pan Z, Hu X, Zheng S, Liu T, Huang P
American journal of respiratory cell and molecular biology 2025 Apr;72(4):364-379
American journal of respiratory cell and molecular biology 2025 Apr;72(4):364-379
Plasma-Derived Exosomal i-tRF-LeuCAA as Biomarker for Glioma Diagnosis and Promoter of Epithelial-Mesenchymal Transition via TPM4 Regulation.
Liu H, Hu W, Zhang L, Li Z, Liu J, Chen L
CNS neuroscience & therapeutics 2025 Apr;31(4):e70356
CNS neuroscience & therapeutics 2025 Apr;31(4):e70356
tRF-34-P4R8YP9LON4VHM Promotes Hepatocellular Carcinoma Progression and Tumour Cell-Induced Angiogenesis via the MEK/ERK Pathway.
Xu T, Hua H, Song F, Zhang N, Gao C, Chen Z
Journal of cellular and molecular medicine 2025 Apr;29(8):e70560
Journal of cellular and molecular medicine 2025 Apr;29(8):e70560
Elevated CD47 Expression Impairs Elimination of Photoaged Fibroblasts by Macrophages and Serves as a Potential Biomarker for Photoaging.
Xu X, Lu X, Chen X, Yao A, Lai W
Journal of cosmetic dermatology 2025 Apr;24(4):e70098
Journal of cosmetic dermatology 2025 Apr;24(4):e70098
Bioinformatics Combined With Biological Experiments to Identify the Pathogenetic Link of Type 2 Diabetes for Breast Cancer.
Bao X, Zeng Z, Tang W, Li D, Fan X, Chen K, Wang Y, Ai W, Yang Q, Liu S, Chen T
Cancer medicine 2025 Apr;14(7):e70759
Cancer medicine 2025 Apr;14(7):e70759
The CD163 + tissue-infiltrating macrophages regulate ferroptosis in thyroid-associated ophthalmopathy orbital fibroblasts via the TGF-β/Smad2/3 signaling pathway.
Li X, Wang S, Cao H, Xu S, Xiong C, Yu J, Chen Y, Ren Z, Li M, Hu Y, Gan P, Xu Q, Wang Y, Liao H
Journal of translational medicine 2025 Apr 10;23(1):423
Journal of translational medicine 2025 Apr 10;23(1):423
A Hybrid Manganese Nanoparticle Simultaneously Eliminates Cancer Stem Cells and Activates STING Pathway to Potentiate Cancer Immunotherapy.
Wu Y, Diao P, Peng Y, Yang Y, Wang Y, Lv P, Li J, Wang D, Cai T, Cheng J
ACS nano 2025 Apr 1;19(12):12237-12252
ACS nano 2025 Apr 1;19(12):12237-12252
Huaier suppresses cell viability, migration and invasion in human non-small cell lung cancer via lncRNA DLEU2/miR-212-5p/ELF3 axis.
Wu T, Liu S, Chen W, Zhao D, Lu Z
International journal of medical sciences 2024;21(2):319-331
International journal of medical sciences 2024;21(2):319-331
Melatonin serves as a novel treatment in bladder fibrosis through TGF-β1/Smad and EMT.
Zhang Y, Gong S, He W, Yuan J, Dong D, Zhang J, Wang H, Chen B
PloS one 2024;19(3):e0295104
PloS one 2024;19(3):e0295104
Highly Ordered Nanotube-Like Microstructure on Titanium Dental Implant Surface Fabricated via Anodization Enhanced Cell Adhesion and Migration of Human Gingival Fibroblasts.
Deng Z, Yu L, Kuang Y, Zhou Z, Li X
International journal of nanomedicine 2024;19:2469-2485
International journal of nanomedicine 2024;19:2469-2485
Localized Administration of Bcar3 siRNA via Nano-Self-Assembly to Treat Idiopathic Pulmonary Fibrosis by Disrupting Macrophage-Fibroblast Crosstalk.
Zeng C, Wang Q, Liu X, Wang K, Wang C, Ju X, Wang T, Zhou Q, Fu X, Yu J, Wang Y
International journal of nanomedicine 2024;19:1827-1842
International journal of nanomedicine 2024;19:1827-1842
Progerin Inhibits the Proliferation and Migration of Melanoma Cells by Regulating the Expression of Paxillin.
Liu W, Huang X, Luo W, Liu X, Chen W
OncoTargets and therapy 2024;17:227-242
OncoTargets and therapy 2024;17:227-242
Cross-border regulation of the STK39/MAPK14 pathway by Lycium barbarum miR166a to inhibit triple-negative breast cancer.
Hou Y, Li J, Li X, Lv Y, Yuan C, Tian J, Liu X
American journal of translational research 2024;16(6):2683-2698
American journal of translational research 2024;16(6):2683-2698
MiR-383-5p inhibits the proliferation and migration of lung adenocarcinoma cells by targeting SHMT2.
Bi X, Wang L, Li H, Ma Y, Guo R, Yue J, Kong L, Gong X, Jiao F, Chinn E, Hu J
Journal of Cancer 2024;15(9):2746-2758
Journal of Cancer 2024;15(9):2746-2758
DOK1 facilitates the advancement of ccRCC.
Xie W, Zhang Y, Shu B, Zhang Z, Zhang R
Journal of Cancer 2024;15(19):6213-6222
Journal of Cancer 2024;15(19):6213-6222
MLPH regulates EMT in pancreatic adenocarcinoma through the PI3K-AKT signaling pathway.
Wei M, Yang X, Yang X, Huang Y, Yuan Z, Huang J, Wei J, Tian L
Journal of Cancer 2024;15(17):5828-5838
Journal of Cancer 2024;15(17):5828-5838
ITGAX promotes gastric cancer progression via epithelial-mesenchymal transition pathway.
Hu J, Cao J, Huang S, Chen Y
Frontiers in pharmacology 2024;15:1536478
Frontiers in pharmacology 2024;15:1536478
NUP155 and NDC1 interaction in NSCLC: a promising target for tumor progression.
Li KM, Meng LF, Yang ZH, Hu WT
Frontiers in pharmacology 2024;15:1514367
Frontiers in pharmacology 2024;15:1514367
The mechanism of PDE7B inhibiting the development of hepatocellular carcinoma through oxidative stress.
Luo Y, Gao H, Zhao J, Chen L, Shao J, Ju L
Frontiers in immunology 2024;15:1469740
Frontiers in immunology 2024;15:1469740
Identification and verification of the optimal feature genes of ferroptosis in thyroid-associated orbitopathy.
Li X, Xiong C, Wang S, Ren Z, Jin Q, Yu J, Chen Y, Gan P, Xu Q, Wang Y, Liao H
Frontiers in immunology 2024;15:1422497
Frontiers in immunology 2024;15:1422497
The long non-coding RNA CCAT1 promotes erlotinib resistance in cholangiocarcinoma by inducing epithelial-mesenchymal transition via the miR-181a-5p/ROCK2 axis.
Zhou W, Li X, Zhang B, Peng H, Quan C, Xiao X, Luo M, Huang Y, Xu D, Huang K, Jin Q, Lu S
American journal of cancer research 2024;14(6):2852-2867
American journal of cancer research 2024;14(6):2852-2867
Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma.
Qin LN, Zhang H, Li QQ, Wu T, Cheng SB, Wang KW, Shi Y, Ren HR, Xing XW, Yang C, Sun T
Theranostics 2024;14(1):436-450
Theranostics 2024;14(1):436-450
Characterization and arbovirus susceptibility of cultured CERNI cells derived from sika deer (Cervus nippon).
Takeishi M, Morikawa S, Kuwata R, Kawaminami M, Shimoda H, Isawa H, Maeda K, Yoshikawa Y
In vitro cellular & developmental biology. Animal 2024 Sep;60(8):935-948
In vitro cellular & developmental biology. Animal 2024 Sep;60(8):935-948
Recombinant humanized type I collagen remodels decidual immune microenvironment at maternal-fetal interface by modulating Th17/Treg imbalance.
Wang L, Zeng H, Li H, Dai J, You S, Jiang H, Wei Q, Dong Z, Liu S, Ren J, Zhu Y, Yang X, He F, Hu L
International journal of biological macromolecules 2024 Sep;276(Pt 2):133994
International journal of biological macromolecules 2024 Sep;276(Pt 2):133994
Mitochondrial dysfunction-associated alveolar epithelial senescence is involved in CdCl(2)-induced COPD-like lung injury.
Peng K, Yao YX, Lu X, Wang WJ, Zhang YH, Zhao H, Wang H, Xu DX, Tan ZX
Journal of hazardous materials 2024 Sep 5;476:135103
Journal of hazardous materials 2024 Sep 5;476:135103
Cigarette smoke extract induces malignant transformation and DNA damage via c-MET phosphorylation in human bronchial epithelial cells.
Wang L, Chen J, Li Q, Liu A, Lei Z, Li M, Yasin P, Yang S, Ren J, Hu Y, Ren Y, Cheng S, Liu Z
Ecotoxicology and environmental safety 2024 Sep 15;283:116985
Ecotoxicology and environmental safety 2024 Sep 15;283:116985
LncRNA HIF1A-AS2 promotes triple-negative breast cancer progression and paclitaxel resistance via MRPS23 protein.
Min L, Chen L, Huang D, Zhang Y, You A, Yan X, Li ZH
Heliyon 2024 Sep 15;10(17):e36469
Heliyon 2024 Sep 15;10(17):e36469
Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway: Screening of natural products using WGCNA and CMAP platforms.
Wang Y, Chen SJ, Ma T, Long Q, Chen L, Xu KX, Cao Y
International immunopharmacology 2024 Sep 10;138:112517
International immunopharmacology 2024 Sep 10;138:112517
Anti-cancer effects of nitazoxanide in epithelial ovarian cancer in-vitro and in-vivo.
Yang X, Liu Z, Wang X, Tian W, Zhao T, Yang Q, Li W, Yang L, Yang H, Jia Y
Chemico-biological interactions 2024 Sep 1;400:111176
Chemico-biological interactions 2024 Sep 1;400:111176
Multi-omics analysis reveals BZW1's regulation of EMT via the Wnt pathway in lung adenocarcinoma.
Lai W, Ping Z, Chen Y, Wang J, Liu Y, Zou S, Wang J, Zhang T, Ren W, Wang W
Journal of cellular and molecular medicine 2024 Oct;28(20):e70163
Journal of cellular and molecular medicine 2024 Oct;28(20):e70163
Single-cell analysis reveals alternations between the aged and young mice prostates.
Li Y, Ding Y, Hou Y, Liu L, Liu Z, Yao Z, Shi P, Li J, Chen K, Hu J
Biomarker research 2024 Oct 9;12(1):117
Biomarker research 2024 Oct 9;12(1):117
SMYD2 Promotes Calcium Oxalate-Induced Glycolysis in Renal Tubular Epithelial Cells via PTEN Methylation.
Pan S, Yuan T, Xia Y, Yu W, Li H, Rao T, Ye Z, Li L, Zhou X, Cheng F
Biomedicines 2024 Oct 8;12(10)
Biomedicines 2024 Oct 8;12(10)
Selenium supplementation elevated SELENBP1 to inhibit fibroblast activation in pulmonary arterial hypertension.
Liang B, Lin W, Tang Y, Li T, Chen Q, Zhang W, Zhou X, Ma J, Liu B, Yu Z, Zha L, Zhang M
iScience 2024 Oct 18;27(10):111036
iScience 2024 Oct 18;27(10):111036
Chromosome 8q24 amplification associated with human hepatocellular carcinoma predicts MYC/ZEB1/MIZ1 transcriptional regulation.
Chahine JJ, Davis SS, Culfaci S, Kallakury BV, Tuma PL
Scientific reports 2024 Oct 18;14(1):24488
Scientific reports 2024 Oct 18;14(1):24488
A living organoid biobank of patients with Crohn's disease reveals molecular subtypes for personalized therapeutics.
Tindle C, Fonseca AG, Taheri S, Katkar GD, Lee J, Maity P, Sayed IM, Ibeawuchi SR, Vidales E, Pranadinata RF, Fuller M, Stec DL, Anandachar MS, Perry K, Le HN, Ear J, Boland BS, Sandborn WJ, Sahoo D, Das S, Ghosh P
Cell reports. Medicine 2024 Oct 15;5(10):101748
Cell reports. Medicine 2024 Oct 15;5(10):101748
NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.
Yun F, Wu N, Yi X, Zhang X, Feng Y, Ni Q, Gai Y, Li E, Yang Z, Zhang Q, Sai B, Kuang Y, Zhu Y
Cell death & disease 2024 Oct 1;15(10):720
Cell death & disease 2024 Oct 1;15(10):720
Immunohistochemical and ultrastructural identification of telocytes in the infantile hemangioma.
Ding HW, Wang Q, Wang M, Chen Y, Yuan SM
Ultrastructural pathology 2024 Nov;48(6):563-574
Ultrastructural pathology 2024 Nov;48(6):563-574
NEU4-mediated desialylation enhances the activation of the oncogenic receptors for the dissemination of ovarian carcinoma.
Shi J, Zhou R, Wang S, Liu Y, Tian B, Liu Y, Chen Y, Hu T, Mu Y, Wang S, Shao X, Yan J, Qu P, Wei D, Yang S, Shi Y, Li J, Wang L
Oncogene 2024 Nov;43(49):3556-3569
Oncogene 2024 Nov;43(49):3556-3569
Effect and underlying mechanism of a photochemotherapy dual-function nanodrug delivery system for head and neck squamous cell carcinoma.
Lin Q, Liu HM, Wu LZ, Yu DD, Hua CY, Zou Y, Jiao WE, Li XP, Chen SM
Journal of translational medicine 2024 Nov 19;22(1):1043
Journal of translational medicine 2024 Nov 19;22(1):1043
Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis.
Li X, Chen Y, Lu R, Hu M, Gu L, Huang Q, Meng W, Zhu H, Fan C, Zhou Z, Mo X
Oncogene 2024 May;43(20):1506-1521
Oncogene 2024 May;43(20):1506-1521
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
Huang Q, Chu Z, Wang Z, Li Q, Meng S, Lu Y, Ma K, Cui S, Hu W, Zhang W, Wei Q, Qu Y, Li H, Fu X, Zhang C
Nature communications 2024 May 9;15(1):3904
Nature communications 2024 May 9;15(1):3904
Engineered keratin/bFGF hydrogel to promote diabetic wound healing in rats.
Sun C, Huang Y, Wang L, Deng J, Qing R, Ge X, Han X, Zha G, Pu W, Wang B, Hao S
International journal of biological macromolecules 2024 Mar;261(Pt 1):129725
International journal of biological macromolecules 2024 Mar;261(Pt 1):129725
LncRNA-SNHG5 mediates activation of hepatic stellate cells by regulating NF2 and Hippo pathway.
Zhang R, Zhan Y, Lang Z, Li Y, Zhang W, Zheng J
Communications biology 2024 Mar 4;7(1):266
Communications biology 2024 Mar 4;7(1):266
Integrative analysis of metabolism subtypes and identification of prognostic metabolism-related genes for glioblastoma.
Li J, Wei Y, Liu J, Cheng S, Zhang X, Qiu H, Li J, He C
Bioscience reports 2024 Mar 29;44(3)
Bioscience reports 2024 Mar 29;44(3)
Comprehensive analysis of zinc and ring finger 3 in prognostic value and pan-cancer immunity.
Liu M, Zhao H, Peng S, Wu Y, Liu Y, Sun W, Zen K, Sun X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23523
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23523
TRPC6 Knockout Alleviates Renal Fibrosis through PI3K/AKT/GSK3B Pathway.
Sun AB, Li FH, Zhu L, Zeng XX, Zhu M, Lei QH, Liao YH
Current medical science 2024 Jun;44(3):589-602
Current medical science 2024 Jun;44(3):589-602
Expression, characterization and antivascular activity of amino acid sequence repeating collagen hexadecapeptide.
Yan W, Huang C, Yan Y, Wang P, Yuwen W, Zhu C, Fu R, Duan Z, Fan D
International journal of biological macromolecules 2024 Jun;270(Pt 1):131886
International journal of biological macromolecules 2024 Jun;270(Pt 1):131886
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Wang J, Du J, Wang Y, Song Y, Wu J, Wang T, Yu Z, Song B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Kokusaginine attenuates renal fibrosis by inhibiting the PI3K/AKT signaling pathway.
Wang Y, Han Y, Shang K, Xiao J, Tao L, Peng Z, Liu S, Jiang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116695
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116695
OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway.
Wei H, Li W, Zeng L, Ding N, Li K, Yu H, Jiang F, Yin H, Xia Y, Deng C, Cai N, Chen X, Gu L, Chen H, Zhang F, He Y, Li J, Zhang C
Molecular cancer 2024 Jun 7;23(1):124
Molecular cancer 2024 Jun 7;23(1):124
Endothelial-to-Mesenchymal Transition in an Hereditary Hemorrhagic Telangiectasia-like Pediatric Case of Multiple Pulmonary Arteriovenous Malformations.
Lorente-Herraiz L, Cuesta AM, Recio-Poveda L, Botella LM, Albiñana V
International journal of molecular sciences 2024 Jun 3;25(11)
International journal of molecular sciences 2024 Jun 3;25(11)
ISG15 promotes tumor progression via IL6/JAK2/STAT3 signaling pathway in ccRCC.
Xie W, Zhang Y, Zhang Z, Li Q, Tao L, Zhang R
Clinical and experimental medicine 2024 Jun 29;24(1):140
Clinical and experimental medicine 2024 Jun 29;24(1):140
MEX3A promotes colorectal cancer migration, invasion and EMT via regulating the Wnt/β-catenin signaling pathway.
Xu J, Chen S, Hao T, Liu G, Zhang K, Zhang C, He Y
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):319
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):319
Study on the mechanism of S100A4-mediated cancer oncogenesis in uveal melanoma cells through the integration of bioinformatics and in vitro experiments.
Chen H, Zhang W, Shi J, Tang Y, Chen X, Li J, Yao X
Gene 2024 Jun 15;911:148333
Gene 2024 Jun 15;911:148333
Lysine acetyltransferase 14 mediates TGF-β-induced fibrosis in ovarian endometrioma via co-operation with serum response factor.
Gong Y, Liu M, Zhang Q, Li J, Cai H, Ran J, Ma L, Ma Y, Quan S
Journal of translational medicine 2024 Jun 12;22(1):561
Journal of translational medicine 2024 Jun 12;22(1):561
Direct contact between tumor cells and platelets initiates a FAK-dependent F3/TGF-β positive feedback loop that promotes tumor progression and EMT in osteosarcoma.
Shi Q, Xu J, Chen C, Hu X, Wang B, Zeng F, Ren T, Huang Y, Guo W, Tang X, Ji T
Cancer letters 2024 Jun 1;591:216902
Cancer letters 2024 Jun 1;591:216902
FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease.
Jiang C, Yao D, Liu Z, Zheng Y, Chen M, Yim WY, Zheng Q, Zhang T, Fan L, Fan Z, Geng B, Tian R, Zhou T, Qiao W, Shi J, Li F, Xu L, Huang Y, Dong N
Redox biology 2024 Jul;73:103215
Redox biology 2024 Jul;73:103215
Expression analysis and biological regulation of silencing regulatory protein 6 (SIRT6) in cutaneous squamous cell carcinoma.
Chen S, Chen H, Wang X, Zhang D, Zhang L, Cheng J, Zhang Q, Hua Z, Miao X, Shi J
Anais brasileiros de dermatologia 2024 Jul-Aug;99(4):535-545
Anais brasileiros de dermatologia 2024 Jul-Aug;99(4):535-545
Silencing SPP1 in M2 macrophages inhibits the progression of castration-resistant prostate cancer via the MMP9/TGFβ1 axis.
Chen S, Deng B, Zhao F, You H, Liu Y, Xie L, Song G, Zhou Z, Huang G, Shen W
Translational andrology and urology 2024 Jul 31;13(7):1239-1255
Translational andrology and urology 2024 Jul 31;13(7):1239-1255
Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
Yang S, Zhang D, Sun Q, Nie H, Zhang Y, Wang X, Huang Y, Sun Y
Cancer research 2024 Jul 2;84(13):2202-2217
Cancer research 2024 Jul 2;84(13):2202-2217
A new mechanism in negative pressure wound therapy: interleukin-17 alters chromatin accessibility profiling.
Xiao S, Wang W, Zhao C, Ren P, Dong L, Zhang H, Ma F, Li X, Bian Y
American journal of physiology. Cell physiology 2024 Jul 1;327(1):C193-C204
American journal of physiology. Cell physiology 2024 Jul 1;327(1):C193-C204
Pro-osteogenic role of interleukin-22 in calcific aortic valve disease.
Deng H, Li H, Liu Z, Shen N, Dong N, Deng C, Liu F
Atherosclerosis 2024 Jan;388:117424
Atherosclerosis 2024 Jan;388:117424
TESC acts as a prognostic factor and promotes epithelial-mesenchymal transition progression in esophageal squamous carcinoma.
Dong Y, Fan B, Li M, Zhang J, Xie S, Di S, Jia Q, Gong T
Pathology, research and practice 2024 Jan;253:154964
Pathology, research and practice 2024 Jan;253:154964
Transcriptomics Reveals the Mechanism of Platycodin D Targeting TGFβ for Anti-Lung Cancer Activity.
Feng M, Wang XJ, Liu Y, Zhang W, Wang Y, Zhang C, Bao S
Integrative cancer therapies 2024 Jan-Dec;23:15347354241263041
Integrative cancer therapies 2024 Jan-Dec;23:15347354241263041
Nuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1.
Huang Y, Peng Q, Tian X, Chen C, Zhu X, Huang C, Huo Z, Liu Y, Yang C, Liu C, Zhang P
Nature communications 2024 Jan 5;15(1):296
Nature communications 2024 Jan 5;15(1):296
Chitosan inhibits vascular intimal hyperplasia via LINC01615/MIR-185-5p/PIK3R2 signaling pathway.
Yan Y, Wu Q, Li JH, Wei X, Xiao J, Yang L, Xie A, Zhang L, Mei WJ, Yang YJ, Zeng Y, Wen D, Deng LJ, Zheng LF
Gene 2024 Jan 20;892:147850
Gene 2024 Jan 20;892:147850
EMP3 as a prognostic biomarker correlates with EMT in GBM.
Li L, Xia S, Zhao Z, Deng L, Wang H, Yang D, Hu Y, Ji J, Huang D, Xin T
BMC cancer 2024 Jan 17;24(1):89
BMC cancer 2024 Jan 17;24(1):89
CSTB accelerates the progression of hepatocellular carcinoma via the ERK/AKT/mTOR signaling pathway.
Zhu W, Dong X, Tian N, Feng Z, Zhou W, Song W
Heliyon 2024 Jan 15;10(1):e23506
Heliyon 2024 Jan 15;10(1):e23506
Targeting blood brain barrier-Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats.
Ma Y, Sun W, Bai J, Gao F, Ma H, Liu H, Hu J, Xu C, Zhang X, Liu Z, Yuan T, Sun C, Huang Y, Wang R
CNS neuroscience & therapeutics 2024 Feb;30(2):e14613
CNS neuroscience & therapeutics 2024 Feb;30(2):e14613
JAM2 is a prognostic biomarker and inhibits proliferation, metastasis and epithelial-mesenchymal transition in lung adenocarcinoma.
Dong Y, Zhang J, Xie S, Di S, Fan B, Gong T
The journal of gene medicine 2024 Feb;26(2):e3679
The journal of gene medicine 2024 Feb;26(2):e3679
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway.
Zhou H, Li J, He Y, Xia X, Liu J, Xiong H
Cancer cell international 2024 Feb 24;24(1):85
Cancer cell international 2024 Feb 24;24(1):85
High CD133 expression in proximal tubular cells in diabetic kidney disease: good or bad?
Zhang Y, Xu L, Guo C, Li X, Tian Y, Liao L, Dong J
Journal of translational medicine 2024 Feb 16;22(1):159
Journal of translational medicine 2024 Feb 16;22(1):159
Bromodomain containing 4 inhibition combats gastric precancerous lesions via modulating macrophage polarization.
Zhu L, Cai Q, Li G, Zou X
Tissue & cell 2024 Dec;91:102580
Tissue & cell 2024 Dec;91:102580
The unfolded protein response sensor PERK mediates mechanical stress-induced maturation of focal adhesion complexes in glioblastoma cells.
Khoonkari M, Liang D, Kamperman M, van Rijn P, Kruyt FAE
FEBS letters 2024 Dec;598(24):3021-3035
FEBS letters 2024 Dec;598(24):3021-3035
Adaptor protein CEMIP reduces the chemosensitivity of small cell lung cancer via activation of an SRC-YAP oncogenic module.
Shen XJ, Wei HL, Mo XC, Mo XX, Li L, He JC, Wei XY, Qin XJ, Xing SP, Luo Z, Chen ZQ, Yang J
Acta pharmacologica Sinica 2024 Dec;45(12):2657-2671
Acta pharmacologica Sinica 2024 Dec;45(12):2657-2671
G protein-coupled receptor kinase 2 as a novel therapeutic target for gland fibrosis of Sjögren's syndrome.
Fang RH, Zhou ZW, Chu R, Guan QY, He F, Ge ML, Guo PP, Wu HX, Yao LL, Wei W, Ma Y, Wang QT
Acta pharmacologica Sinica 2024 Dec;45(12):2611-2624
Acta pharmacologica Sinica 2024 Dec;45(12):2611-2624
Circular RNA circWBSCR22 facilitates colorectal cancer metastasis by enhancing CHD4's protein stability.
Luo J, Xu S, Wang J, He L, Li Z
International journal of biological macromolecules 2024 Dec;282(Pt 4):137135
International journal of biological macromolecules 2024 Dec;282(Pt 4):137135
Hypoxia-driven heterogeneous expression of α5 integrin in glioblastoma stem cells is linked to HIF-2α.
Messé M, Bernhard C, Foppolo S, Thomas L, Marchand P, Herold-Mende C, Idbaih A, Kessler H, Etienne-Selloum N, Ochoa C, Tambar UK, Elati M, Laquerriere P, Entz-Werle N, Martin S, Reita D, Dontenwill M
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167471
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167471
Expression of SARS-CoV-2 entry molecules ACE2, NRP1, TMPRSS2, and FURIN in the reproductive tissues of male macaques.
Moriyama R, Nakamura S, Mitsui I, Sugiyama M, Fukui H, Fukui H, Hagiwara T, Miyabe-Nishiwaki T, Suzuki J
Histochemistry and cell biology 2024 Dec;162(6):465-475
Histochemistry and cell biology 2024 Dec;162(6):465-475
RRM2 Regulates Hepatocellular Carcinoma Progression Through Activation of TGF-β/Smad Signaling and Hepatitis B Virus Transcription.
Wu D, Sun X, Li X, Zuo Z, Yan D, Yin W
Genes 2024 Dec 6;15(12)
Genes 2024 Dec 6;15(12)
OCTN2 expression and function in the Sertoli cells of testes from patients with non-obstructive azoospermia.
Li D, Jiang N, Pan M, Ma L, Huang Y, Xu X, Yang X, Zhu Y, Shi H, Zhao SC
Journal of molecular histology 2024 Dec 5;56(1):31
Journal of molecular histology 2024 Dec 5;56(1):31
Ancestry-linked stromal variations impact breast epithelial cell invasion.
Schmidtmann M, Elliott V, Clancy J, Nakshatri H, D'Souza-Schorey C
bioRxiv : the preprint server for biology 2024 Dec 26;
bioRxiv : the preprint server for biology 2024 Dec 26;
IGFALS suppresses hepatocellular carcinoma progression by stabilizing PPAR-γ.
Xu L, Xiong L, Chen Y, Chen J, Liu X, Xu Y, Shen Y, Wang S, Yu S, Xu X
International immunopharmacology 2024 Dec 25;143(Pt 2):113414
International immunopharmacology 2024 Dec 25;143(Pt 2):113414
Identification of UNC5B as a novel aggressive biomarker for osteosarcoma based on basement membrane genes.
Pan R, Zhang Y, Cheng Y, Wu Z, Liu J, Chen Z, Wang J, Zhang X, Wang H, Feng S, Zheng X
Gene 2024 Dec 20;930:148871
Gene 2024 Dec 20;930:148871
miR-200a-3p inhibits the PDGF-BB-induced proliferation of VSMCs by affecting their phenotype-associated proteins.
Zeng RY, Jin HY, Peng YB, Wang WJ, Cao YP, Peng HZ, Qiu ZC, Lai SQ, Wan L
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23675
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23675
Microbial imidazole propionate affects glomerular filtration rate in patients with diabetic nephropathy through association with HSP90α.
Lv D, Zheng W, Zhang Z, Lin Z, Wu K, Liu H, Liao X, Sun Y
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119703
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119703
PlexinA1 promotes gastric cancer migration through preventing MICAL1 protein ubiquitin/proteasome-mediated degradation in a Rac1-dependent manner.
Ye F, Xia T, Zhao M, Zhao W, Min P, Wang Y, Wang Q, Zhang Y, Du J
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167124
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167124
Deubiquitinase OTUD6a drives cardiac inflammation and hypertrophy by deubiquitination of STING.
Fang Z, Han J, Lin L, Ye B, Qu X, Zhang Y, Zhao Y, Xu D, Lin W, Shen S, Min J, Wu G, Huang Z, Liang G
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167061
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167061
Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis.
Liu B, Xian Y, Chen X, Shi Y, Dong J, Yang L, An X, Shen T, Wu W, Ma Y, He Y, Gong W, Peng R, Lin J, Liu N, Guo B, Jiang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307338
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2307338
Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction.
He C, Yu Y, Wang F, Li W, Ni H, Xiang M
European journal of histochemistry : EJH 2024 Apr 29;68(2)
European journal of histochemistry : EJH 2024 Apr 29;68(2)
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
Zhang M, Cai F, Guo J, Liu S, Ma G, Cai M, Zhang R, Deng J
Cell death & disease 2024 Apr 26;15(4):297
Cell death & disease 2024 Apr 26;15(4):297
Melt electrowriting-printed peritoneal scaffold prevents peritoneal adhesion and facilitates peritoneal repair.
Li S, Huang J, Xu Z, Liu Y, Ren H, Li Z, Chen C, Chen K, Wu X, Ren J
International journal of bioprinting 2023;9(3):682
International journal of bioprinting 2023;9(3):682
Caffeic acid phenethyl ester suppresses metastasis of breast cancer cells by inactivating FGFR1 via MD2.
Fang Q, Xin W, Chen L, Fu Y, Qi Y, Ding H, Fang L
PloS one 2023;18(7):e0289031
PloS one 2023;18(7):e0289031
Sevoflurane Improves Ventricular Conduction by Exosomes Derived from Rat Cardiac Fibroblasts After Hypothermic Global Ischemia-Reperfusion Injury.
Ma Y, Cao Y, Gao H, Tong R, Yi J, Zhang Z, Chen R, Pan Z
Drug design, development and therapy 2023;17:1719-1732
Drug design, development and therapy 2023;17:1719-1732
Expression profiles of α-synuclein in cortical lesions of patients with FCD IIb and TSC, and FCD rats.
Zhang L, Huang J, Dai L, Zhu G, Yang XL, He Z, Li YH, Yang H, Zhang CQ, Shen KF, Liang P
Frontiers in neurology 2023;14:1255097
Frontiers in neurology 2023;14:1255097
Tocilizumab (monoclonal anti-IL-6R antibody) reverses anlotinib resistance in osteosarcoma.
Xu J, Chen C, Sun K, Shi Q, Wang B, Huang Y, Ren T, Tang X
Frontiers in oncology 2023;13:1192472
Frontiers in oncology 2023;13:1192472
UCHL3 promotes hepatocellular carcinoma cell migration by de-ubiquitinating and stabilizing Vimentin.
Ma Q, Lu Q, Lei X, Zhao J, Sun W, Wang J, Zhu Q, Huang D
Frontiers in oncology 2023;13:1088475
Frontiers in oncology 2023;13:1088475
Bioinformatics prediction and experimental verification of a novel microRNA for myocardial fibrosis after myocardial infarction in rats.
Guo Q, Wu D, Jia D, Zhang X, Wu A, Lou L, Zhao M, Zhao M, Gao Y, Wang M, Liu M, Chen M, Zhang D
PeerJ 2023;11:e14851
PeerJ 2023;11:e14851
The NLRP11 Protein Bridges the Histone Lysine Acetyltransferase KAT7 to Acetylate Vimentin in the Early Stage of Lung Adenocarcinoma.
Yang R, Peng W, Shi S, Peng X, Cai Q, Zhao Z, He B, Tu G, Yin W, Chen Y, Zhang Y, Liu F, Wang X, Xiao D, Tao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2300971
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2300971
AZGP1 activation by lenvatinib suppresses intrahepatic cholangiocarcinoma epithelial-mesenchymal transition through the TGF-β1/Smad3 pathway.
Deng L, Bao W, Zhang B, Zhang S, Chen Z, Zhu X, He B, Wu L, Chen X, Deng T, Chen B, Yu Z, Wang Y, Chen G
Cell death & disease 2023 Sep 5;14(9):590
Cell death & disease 2023 Sep 5;14(9):590
DKK1 Promotes Epithelial-Mesenchymal Transition and Cisplatin Resistance in Gastric Cancer via Activation of the PI3K/AKT Pathway.
Li J, Zhang Y, Ye F, Qian P, Qin Z, Li D, Ye L, Feng L
Cancers 2023 Sep 27;15(19)
Cancers 2023 Sep 27;15(19)
FAM3A reshapes VSMC fate specification in abdominal aortic aneurysm by regulating KLF4 ubiquitination.
Lei C, Kan H, Xian X, Chen W, Xiang W, Song X, Wu J, Yang D, Zheng Y
Nature communications 2023 Sep 2;14(1):5360
Nature communications 2023 Sep 2;14(1):5360
Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway.
Zhang L, Li W, Liu X, Guo J, Wu X, Wang J
Experimental eye research 2023 Oct;235:109628
Experimental eye research 2023 Oct;235:109628
ACLY promotes gastric tumorigenesis and accelerates peritoneal metastasis of gastric cancer regulated by HIF-1A.
Yan Z, Liu K, Xu P, Chen Z, Zhang P, Pei S, Cheng Q, Huang S, Li B, Lv J, Xu Z, Xu H, Yang L, Zhang D
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2288-2301
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2288-2301
DACH1 regulates macrophage activation and tumour progression in hypopharyngeal squamous cell carcinoma.
Li W, Xu L, Cao J, Ge J, Liu X, Liu P, Teng Y, Wang S, Sun Y, Liu M, Tian L
Immunology 2023 Oct;170(2):253-269
Immunology 2023 Oct;170(2):253-269
Enhanced Mitophagy in Cholesteatoma Epithelial Cells.
Li QC, Wang SQ, Cao ZZ, Zhou SH
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2023 Oct 1;44(9):e688-e694
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2023 Oct 1;44(9):e688-e694
LncBIRC3-OT promotes the malignant progression of glioma by interacting with RELA to upregulate stanniocalcin-1 expression.
Wang R, Li Q, Chu X, Li N, Liang H, He F
Heliyon 2023 Nov;9(11):e21777
Heliyon 2023 Nov;9(11):e21777
Epinodosin suppresses the proliferation, invasion, and migration of esophageal squamous cell carcinoma by mediating miRNA-143-3p/Bcl-2 axis.
Chen H, Li Y, Liu Y, Zhao Y, Xu F, Yang S, Yu M, Zou M, Zhang J
Phytotherapy research : PTR 2023 Nov;37(11):5378-5393
Phytotherapy research : PTR 2023 Nov;37(11):5378-5393
Meroterpenoids from Daphne genkwa shows promising in vitro antitumor activity via inhibiting PI3K/Akt/mTOR signaling pathway in A549 cells.
Ma RF, Liu H, Zhao XC, Shan P, Sun P, Xue JJ, Wei G, Zhang H
Bioorganic chemistry 2023 Nov;140:106803
Bioorganic chemistry 2023 Nov;140:106803
Discovery of a novel dual-target inhibitor of CDK12 and PARP1 that induces synthetic lethality for treatment of triple-negative breast cancer.
Zhang L, Zhen Y, Feng L, Li Z, Lu Y, Wang G, Ouyang L
European journal of medicinal chemistry 2023 Nov 5;259:115648
European journal of medicinal chemistry 2023 Nov 5;259:115648
Hsa_circ_0009092/miR-665/NLK signaling axis suppresses colorectal cancer progression via recruiting TAMs in the tumor microenvironment.
Song J, Liu Q, Han L, Song T, Huang S, Zhang X, He Q, Liang C, Zhu S, Xiong B
Journal of experimental & clinical cancer research : CR 2023 Nov 27;42(1):319
Journal of experimental & clinical cancer research : CR 2023 Nov 27;42(1):319
Metformin Attenuates TGF-β1-Induced Fibrosis in Salivary Gland: A Preliminary Study.
Wang L, Zhong NN, Wang X, Peng B, Chen Z, Wei L, Li B, Li Y, Cheng Y
International journal of molecular sciences 2023 Nov 13;24(22)
International journal of molecular sciences 2023 Nov 13;24(22)
ZD6474 attenuates TGF-β1-induced fibrosis in human Tenon fibroblasts and inhibits neovascularization via AKT-mTOR signaling pathway.
Liu W, Chen Y, Song X, Xue Y, Zhang Y
International ophthalmology 2023 May;43(5):1523-1536
International ophthalmology 2023 May;43(5):1523-1536
Lycopene inhibits endothelial-to-mesenchymal transition of choroidal vascular endothelial cells in laser-induced mouse choroidal neovascularization.
Li L, Cao X, Huang L, Huang X, Gu J, Yu X, Zhu Y, Zhou Y, Song Y, Zhu M
Journal of cellular and molecular medicine 2023 May;27(10):1327-1340
Journal of cellular and molecular medicine 2023 May;27(10):1327-1340
Nicotine exposure exacerbates silica-induced pulmonary fibrosis via STAT3-BDNF-TrkB-mediated epithelial-mesenchymal transition in alveolar type II cells.
Chen H, Tao X, Cao H, Li B, Sun Q, Wang W, Zou Y, Mu M, Tao H, Zhao Y, Ge D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113694
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113694
The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII.
Chen L, Li X, Deng Y, Chen J, Huang M, Zhu F, Gao Z, Wu L, Hong Q, Feng Z, Cai G, Sun X, Bai X, Chen X
Journal of translational medicine 2023 May 13;21(1):323
Journal of translational medicine 2023 May 13;21(1):323
ZD6474 Attenuates Fibrosis and Inhibits Neovascularization in Human Pterygium by Suppressing AKT-mTOR Signaling Pathway.
Liu W, Lin T, Gong L
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2023 Mar;39(2):128-138
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2023 Mar;39(2):128-138
Simple, Fast, and Efficient Method for Derivation of Dermal Fibroblasts From Skin Biopsies.
Iannello G, Patel A, Sirabella D, Diaz AG, Hoover BN, Sarmah H, Corneo B
Current protocols 2023 Mar;3(3):e714
Current protocols 2023 Mar;3(3):e714
Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation.
Cheng X, Jia X, Wang C, Zhou S, Chen J, Chen L, Chen J
World journal of surgical oncology 2023 Mar 28;21(1):112
World journal of surgical oncology 2023 Mar 28;21(1):112
Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling.
Zhang Z, Wu W, Jiao H, Chen Y, Ji X, Cao J, Yin F, Yin W
British journal of pharmacology 2023 Jun;180(12):1562-1581
British journal of pharmacology 2023 Jun;180(12):1562-1581
FGF4 Promotes Skin Wound Repair through p38 MAPK and GSK3β-Mediated Stabilization of Slug.
Sun J, Zhou J, Zhou J, Xu W, Du Y, Jia Z, Shen Y, Lin X, Wang X, Bao Y, Rao Z, Dong S, Luo Y, Cong W, Jin L, Li X
The Journal of investigative dermatology 2023 Jun;143(6):1073-1084.e8
The Journal of investigative dermatology 2023 Jun;143(6):1073-1084.e8
Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway.
Chen J, Liu F, Wu J, Yang Y, He J, Wu F, Yang K, Li J, Jiang Z, Jiang Z
Cellular signalling 2023 Jun;106:110642
Cellular signalling 2023 Jun;106:110642
High glucose promotes the progression of colorectal cancer by activating the BMP4 signaling and inhibited by glucagon-like peptide-1 receptor agonist.
Ma B, Wang X, Ren H, Li Y, Zhang H, Yang M, Li J
BMC cancer 2023 Jun 27;23(1):594
BMC cancer 2023 Jun 27;23(1):594
Activation of Piezo1 promotes osteogenic differentiation of aortic valve interstitial cell through YAP-dependent glutaminolysis.
Zhong G, Su S, Li J, Zhao H, Hu D, Chen J, Li S, Lin Y, Wen L, Lin X, Xian G, Xu D, Zeng Q
Science advances 2023 Jun 2;9(22):eadg0478
Science advances 2023 Jun 2;9(22):eadg0478
ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11.
Fang Q, Li Q, Qi Y, Pan Z, Feng T, Xin W
Cell biology international 2023 Jul;47(7):1209-1221
Cell biology international 2023 Jul;47(7):1209-1221
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Zhang W, Yu L, Xu C, Tang T, Cao J, Chen L, Pang X, Ren W
Oncology letters 2023 Jul;26(1):298
Oncology letters 2023 Jul;26(1):298
Astragaloside IV Blunts Epithelial-Mesenchymal Transition and G2/M Arrest to Alleviate Renal Fibrosis via Regulating ALDH2-Mediated Autophagy.
Li D, Liu Y, Zhan Q, Zeng Y, Peng Z, He Q, Tan Q, Cao W, Wang S, Wang J
Cells 2023 Jul 4;12(13)
Cells 2023 Jul 4;12(13)
Single-cell RNA sequencing reveals that VIM and IFITM3 are vital targets of Dengzhan Shengmai capsule to protect against cerebral ischemic injury.
Cao GZ, Hou JY, Zhou R, Tian LL, Wang ML, Zhang Y, Xu H, Yang HJ, Zhang JJ
Journal of ethnopharmacology 2023 Jul 15;311:116439
Journal of ethnopharmacology 2023 Jul 15;311:116439
Cancer-Associated Fibroblasts Promote Radioresistance of Breast Cancer Cells via the HGF/c-Met Signaling Pathway.
Wang B, Liu W, Liu C, Du K, Guo Z, Zhang G, Huang Z, Lin S, Cen B, Tian Y, Yuan Y, Bu J
International journal of radiation oncology, biology, physics 2023 Jul 1;116(3):640-654
International journal of radiation oncology, biology, physics 2023 Jul 1;116(3):640-654
PLAGL2 increases adriamycin resistance and EMT in breast cancer cells by activating the Wnt pathway.
Li Y, Liu R, Han X, Xu W, Liu Y
Genes & genomics 2023 Jan;45(1):49-57
Genes & genomics 2023 Jan;45(1):49-57
SERPINA5 may promote the development of preeclampsia by disruption of the uPA/uPAR pathway.
Long Y, Zeng S, Gao F, Liu F, Zhang Y, Zhou C, Zhu C, Zhao X, Han M, Gan Q, Ye W, Zeng F, Song C, Jiang M, Lash GE, Yang H
Translational research : the journal of laboratory and clinical medicine 2023 Jan;251:14-26
Translational research : the journal of laboratory and clinical medicine 2023 Jan;251:14-26
LncRNA NR120519 Blocks KRT17 to Promote Cell Proliferation and Migration in Hypopharyngeal Squamous Carcinoma.
Zhou Z, Zhang G, Li T, Ai J, Li W, Zeng S, Ye M, Liu Q, Xiao J, Li Y, Tan G, Zhang X
Cancers 2023 Jan 18;15(3)
Cancers 2023 Jan 18;15(3)
Embryonic 6:2 FTOH exposure causes reproductive toxicity by disrupting the formation of the blood-testis barrier in offspring mice.
Xia Y, Hao L, Li Y, Li Y, Chen J, Li L, Han X, Liu Y, Wang X, Li D
Ecotoxicology and environmental safety 2023 Jan 15;250:114497
Ecotoxicology and environmental safety 2023 Jan 15;250:114497
LncRNA BCAR4 promotes migration, invasion, and chemo-resistance by inhibiting miR-644a in breast cancer.
Wu T, Li X, Yan G, Tan Z, Zhao D, Liu S, Wang H, Xiang Y, Chen W, Lu H, Liao X, Li Y, Lu Z
Journal of experimental & clinical cancer research : CR 2023 Jan 10;42(1):14
Journal of experimental & clinical cancer research : CR 2023 Jan 10;42(1):14
The miR-103a-3p/TGFBR3 axis regulates TGF-β-induced orbital fibroblast activation and fibrosis in thyroid-eye disease.
Xie B, Xiong W, Zhang F, Wang N, Luo Y, Chen Y, Cao J, Chen Z, Ma C, Chen H
Molecular and cellular endocrinology 2023 Jan 1;559:111780
Molecular and cellular endocrinology 2023 Jan 1;559:111780
Huntingtin-associated protein 1 is a potential tumor suppressor for gastric cancer.
Qu YM, Chen A, Zhao X, Wang Z, Guo D, Shao SL, Tao YY, Li QJ, Wang MY, Ma WS
Molecular biology reports 2023 Feb;50(2):1517-1531
Molecular biology reports 2023 Feb;50(2):1517-1531
Umbilical cord mesenchymal stem cell-derived exosomes reverse endometrial fibrosis by the miR-145-5p/ZEB2 axis in intrauterine adhesions.
Li X, Duan H, Wang S, Lv CX
Reproductive biomedicine online 2023 Feb;46(2):234-243
Reproductive biomedicine online 2023 Feb;46(2):234-243
SPON2 promotes the bone metastasis of lung adenocarcinoma via activation of the NF-κB signaling pathway.
Wu M, Kong D, Zhang Y
Bone 2023 Feb;167:116630
Bone 2023 Feb;167:116630
Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics.
Xu H, Bensalel J, Raju S, Capobianco E, Lu ML, Wei J
Journal of neurochemistry 2023 Feb;164(4):512-528
Journal of neurochemistry 2023 Feb;164(4):512-528
Downregulation of CYRI-B promotes migration, invasion and EMT by activating the Rac1-STAT3 pathway in gastric cancer.
Liu G, Xia Y, Wang H, Jin X, Chen S, Chen W, Zhang C, He Y
Experimental cell research 2023 Feb 1;423(1):113453
Experimental cell research 2023 Feb 1;423(1):113453
SOX10 promotes the malignant biological behavior of basal-like breast cancer cells by regulating EMT process.
Yang K, Yun F, Shi L, Liu X, Jia YF
Heliyon 2023 Dec;9(12):e23162
Heliyon 2023 Dec;9(12):e23162
PLCB1 Enhances Cell Migration and Invasion in Gastric Cancer Via Regulating Actin Cytoskeletal Remodeling and Epithelial-Mesenchymal Transition.
Wang Y, Tu Z, Zhao W, Wang L, Jiang J, Gu L, Li M, Jiang L, Wang Y, Bi Y
Biochemical genetics 2023 Dec;61(6):2618-2632
Biochemical genetics 2023 Dec;61(6):2618-2632
Radioprotective efficacy of Astilbin in mitigating radiation-induced lung injury through inhibition of p53 acetylation.
Liang L, Huang Y, Chen L, Shi Z, Wang H, Zhang T, Li Z, Mi J, Fan T, Lu Y, Chen F, Huang W, Hu K
Environmental toxicology 2023 Dec;38(12):2967-2980
Environmental toxicology 2023 Dec;38(12):2967-2980
FAM107A as a tumor suppressor in esophageal squamous carcinoma inhibits growth and metastasis.
Zhang J, Di S, Li M, Dong Y, Xie S, Gong T, Hu P, Jia Q, Fan B
Pathology, research and practice 2023 Dec;252:154945
Pathology, research and practice 2023 Dec;252:154945
Isoliquiritigenin suppresses the progression of malignant melanoma via targeting H2A.Z.1-E2F1 pathway.
Xiang S, Jian L, Zeng H, Wu H, Ge B, Zhang P, Lin J, Guo A, Zhou B
Biochemical pharmacology 2023 Dec;218:115859
Biochemical pharmacology 2023 Dec;218:115859
Aberrant acetylated modification of FGF21‑KLB signaling contributes to hepatocellular carcinoma metastasis through the β‑catenin pathway.
Xia J, Zhu Z, Wen G, Chen Y, An R, Xia S, Guan W, Ren H
International journal of oncology 2023 Aug;63(2)
International journal of oncology 2023 Aug;63(2)
Dipeptidase‑2 is a prognostic marker in lung adenocarcinoma that is correlated with its sensitivity to cisplatin.
Wang Y, Zhang T, Du H, Yang M, Xie G, Liu T, Deng S, Yuan W, He S, Wu D, Xu Y
Oncology reports 2023 Aug;50(2)
Oncology reports 2023 Aug;50(2)
Neonatal-Tissue-Derived Extracellular Vesicle Therapy (NEXT): A Potent Strategy for Precision Regenerative Medicine.
Lou P, Liu S, Wang Y, Lv K, Zhou X, Li L, Zhang Y, Chen Y, Cheng J, Lu Y, Liu J
Advanced materials (Deerfield Beach, Fla.) 2023 Aug;35(33):e2300602
Advanced materials (Deerfield Beach, Fla.) 2023 Aug;35(33):e2300602
Glutamine and amino acid metabolism as a prognostic signature and therapeutic target in endometrial cancer.
Zhai L, Yang X, Cheng Y, Wang J
Cancer medicine 2023 Aug;12(15):16337-16358
Cancer medicine 2023 Aug;12(15):16337-16358
SMC1A facilitates gastric cancer cell proliferation, migration, and invasion via promoting SNAIL activated EMT.
Liu Y, Fang X, Wang Q, Xiao D, Zhou T, Kang K, Peng Z, Ren F, Zhou J
BMC gastroenterology 2023 Aug 4;23(1):268
BMC gastroenterology 2023 Aug 4;23(1):268
CSF2 upregulates CXCL3 expression in adipocytes to promote metastasis of breast cancer via the FAK signaling pathway.
He X, Wang L, Li H, Liu Y, Tong C, Xie C, Yan X, Luo D, Xiong X
Journal of molecular cell biology 2023 Aug 3;15(4)
Journal of molecular cell biology 2023 Aug 3;15(4)
Inhibition of Transglutaminase 2 Reduces Peritoneal Injury in a Chlorhexidine-Induced Peritoneal Fibrosis Model.
Kunoki S, Tatsukawa H, Sakai Y, Kinashi H, Kariya T, Suzuki Y, Mizuno M, Yamaguchi M, Sasakura H, Ikeno M, Takeuchi K, Ishimoto T, Hitomi K, Ito Y
Laboratory investigation; a journal of technical methods and pathology 2023 Apr;103(4):100050
Laboratory investigation; a journal of technical methods and pathology 2023 Apr;103(4):100050
FSBP suppresses tumor cell migration by inhibiting the JNK pathway.
Song F, Zhang W, Li X, Chen X, Yuan X, Jiang M, Zhao Y, Liu Q, Zhou Z
iScience 2023 Apr 21;26(4):106440
iScience 2023 Apr 21;26(4):106440
miR-138-5p Inhibits the Growth and Invasion of Glioma Cells by Regulating WEE1.
Gong J, Tang Z, Yu Z, Deng Z, Liu Y, Ren N, Wang L, He Z
Analytical cellular pathology (Amsterdam) 2022;2022:7809882
Analytical cellular pathology (Amsterdam) 2022;2022:7809882
Plasma-Based Metabolomics Profiling of High-Risk Human Papillomavirus and their Emerging Roles in the Progression of Cervical Cancer.
Chen A, Xu M, Chen J, Chen T, Wang Q, Zhang R, Qiu J
BioMed research international 2022;2022:6207701
BioMed research international 2022;2022:6207701
ARL4C Regulates the Progression of Clear Cell Renal Cell Carcinoma by Affecting the Wnt/β-Catenin Signaling Pathway.
Zhang P, Xu Y, Chen S, Wang Z, Zhao L, Chen C, Kang W, Han R, Qiu J, Wang Q, Gao H, Wu G, Xia Q
Journal of oncology 2022;2022:2724515
Journal of oncology 2022;2022:2724515
LASS2 impairs proliferation of glioma stem cells and migration and invasion of glioma cells mainly via inhibition of EMT and apoptosis promotion.
Zhao WJ, Fan YP, Ou GY, Qiao XY
Journal of Cancer 2022;13(7):2281-2292
Journal of Cancer 2022;13(7):2281-2292
Down-regulation of MSMO1 promotes the development and progression of pancreatic cancer.
Cao R, Zhang Z, Tian C, Sheng W, Dong Q, Dong M
Journal of Cancer 2022;13(10):3013-3021
Journal of Cancer 2022;13(10):3013-3021
Manpixiao Decoction Halted the Malignant Transformation of Precancerous Lesions of Gastric Cancer: From Network Prediction to In-Vivo Verification.
Li Y, Li T, Chen J, Zheng H, Li Y, Chu F, Wang S, Li P, Lin J, Su Z, Ding X
Frontiers in pharmacology 2022;13:927731
Frontiers in pharmacology 2022;13:927731
Deciphering the Mechanism of Bushen Huoxue Decotion on Decidualization by Intervening Autophagy via AMPK/mTOR/ULK1: A Novel Discovery for URSA Treatment.
Zhao X, Jiang Y, Ren J, Wang Y, Zhao Y, Feng X
Frontiers in pharmacology 2022;13:794938
Frontiers in pharmacology 2022;13:794938
Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury.
Li J, Jiang Y, Dai Q, Yu Y, Lv X, Zhang Y, Liao X, Ao L, Hu G, Meng J, Peng Z, Tao L, Xie Y
Frontiers in pharmacology 2022;13:1043945
Frontiers in pharmacology 2022;13:1043945
Protein-protein interactions between RUNX3 and ZEB1 in chronic lung injury induced by methamphetamine abuse.
Bao N, Cheng L, Wang Y, Peng Z, Wang Z, Chen S
Frontiers in pharmacology 2022;13:1025922
Frontiers in pharmacology 2022;13:1025922
Irradiation enhances the malignancy-promoting behaviors of cancer-associated fibroblasts.
Zhang Z, Dong Y, Wu B, Li Y, Liu Z, Liu Z, Gao Y, Gao L, Song Q, Zheng Z, Yao Y
Frontiers in oncology 2022;12:965660
Frontiers in oncology 2022;12:965660
MiR-29b-3p Inhibits Migration and Invasion of Papillary Thyroid Carcinoma by Downregulating COL1A1 and COL5A1.
Wang C, Wang Y, Fu Z, Huang W, Yu Z, Wang J, Zheng K, Zhang S, Li S, Chen J
Frontiers in oncology 2022;12:837581
Frontiers in oncology 2022;12:837581
BCAT1 promotes lung adenocarcinoma progression through enhanced mitochondrial function and NF-κB pathway activation.
Yu M, Zhao Q, Li J, Xu F, Zhang Z, Liu Y, Dai L, Zhang B, Zhang J, Zhang J
Journal of Zhejiang University. Science. B 2022 Sept 15;23(9):760-769
Journal of Zhejiang University. Science. B 2022 Sept 15;23(9):760-769
Effect of Baricitinib on the epithelial-mesenchymal transition of alveolar epithelial cells induced by IL-6.
Liu Y, Hu M, Fan G, Xing N, Zhang R
International immunopharmacology 2022 Sep;110:109044
International immunopharmacology 2022 Sep;110:109044
HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway.
Xiong F, Liu W, Wang X, Wu G, Wang Q, Guo T, Huang W, Wang B, Chen Y
Cell death & disease 2022 Sep 27;13(9):829
Cell death & disease 2022 Sep 27;13(9):829
FTO Inhibits Epithelial Ovarian Cancer Progression by Destabilising SNAI1 mRNA through IGF2BP2.
Sun M, Zhang X, Bi F, Wang D, Zhou X, Li X, Yang Q
Cancers 2022 Oct 25;14(21)
Cancers 2022 Oct 25;14(21)
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Fang J, Ma Y, Li Y, Li J, Zhang X, Han X, Ma S, Guan F
Molecular carcinogenesis 2022 Nov;61(11):1043-1055
Molecular carcinogenesis 2022 Nov;61(11):1043-1055
Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
Wang C, Long Q, Fu Q, Xu Q, Fu D, Li Y, Gao L, Guo J, Zhang X, Lam EW, Campisi J, Sun Y
Oncogene 2022 Nov;41(45):4941-4959
Oncogene 2022 Nov;41(45):4941-4959
Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.
Zhou B, Lei JH, Wang Q, Qu TF, Cha LC, Zhan HX, Liu SL, Hu X, Sun CD, Guo WD, Qiu FB, Cao JY
The Kaohsiung journal of medical sciences 2022 Nov;38(11):1080-1092
The Kaohsiung journal of medical sciences 2022 Nov;38(11):1080-1092
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
Song K, Yang X, An G, Xia X, Zhao J, Xu X, Wan C, Liu T, Zheng Y, Ren S, Wang M, Chang G, Cronin SJF, Penninger JM, Jing T, Ou X, Rao S, Liu Z, Zhao XY
Nature communications 2022 Nov 28;13(1):7335
Nature communications 2022 Nov 28;13(1):7335
Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling.
Li XT, Song JW, Zhang ZZ, Zhang MW, Liang LR, Miao R, Liu Y, Chen YH, Liu XY, Zhong JC
Free radical biology & medicine 2022 Nov 20;193(Pt 1):459-473
Free radical biology & medicine 2022 Nov 20;193(Pt 1):459-473
CircRNA Samd4 induces cardiac repair after myocardial infarction by blocking mitochondria-derived ROS output.
Zheng H, Huang S, Wei G, Sun Y, Li C, Si X, Chen Y, Tang Z, Li X, Chen Y, Liao W, Liao Y, Bin J
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Nov 2;30(11):3477-3498
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Nov 2;30(11):3477-3498
Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.
Ling X, Lu J, Wang X, Liu L, Liu L, Wang Y, Sun Y, Ren C, Lu C, Yu Z
iScience 2022 Nov 18;25(11):105363
iScience 2022 Nov 18;25(11):105363
FGF2 isoforms play distinct roles in tubular epithelial-to-mesenchymal transition in diabetic nephropathy.
Luo Y, Deng D, Lin L, Zhou Y, Wang L, Zou X, Wang X
Experimental cell research 2022 Nov 15;420(2):113355
Experimental cell research 2022 Nov 15;420(2):113355
Single-Cell RNA Sequencing Technology Revealed the Pivotal Role of Fibroblast Heterogeneity in Angiotensin II-Induced Abdominal Aortic Aneurysms.
Weng Y, Lou J, Bao Y, Cai C, Zhu K, Du C, Chen X, Tang L
DNA and cell biology 2022 May;41(5):498-520
DNA and cell biology 2022 May;41(5):498-520
Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1.
Luo P, Liu D, Zhang Q, Yang F, Wong YK, Xia F, Zhang J, Chen J, Tian Y, Yang C, Dai L, Shen HM, Wang J
Acta pharmaceutica Sinica. B 2022 May;12(5):2300-2314
Acta pharmaceutica Sinica. B 2022 May;12(5):2300-2314
FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression.
Zhu J, Zhao J, Luo C, Zhu Z, Peng X, Zhu X, Lin K, Bu F, Zhang W, Li Q, Wang K, Hu Z, Yu X, Chen L, Yuan R
Cell death & disease 2022 May 25;13(5):497
Cell death & disease 2022 May 25;13(5):497
Tofacitinib May Inhibit Myofibroblast Differentiation from Rheumatoid-Fibroblast-like Synoviocytes Induced by TGF-β and IL-6.
Ruscitti P, Liakouli V, Panzera N, Angelucci A, Berardicurti O, Di Nino E, Navarini L, Vomero M, Ursini F, Mauro D, Dolo V, Ciccia F, Giacomelli R, Cipriani P
Pharmaceuticals (Basel, Switzerland) 2022 May 18;15(5)
Pharmaceuticals (Basel, Switzerland) 2022 May 18;15(5)
Transcriptomic investigation of the effects of TDCPP on PC12 and GC2 cells with experimental validation.
Zhang X, Zhang Q, Shan Y, Xiao J, Cheng J, Ye F, Sai Y
Gene 2022 May 15;822:146349
Gene 2022 May 15;822:146349
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.
Hu Y, Zhang P, Shi Y, Dong X, Wu Y, Dong D, Li E, Fan Y
Environmental toxicology 2022 Mar;37(3):527-538
Environmental toxicology 2022 Mar;37(3):527-538
P16ink4a overexpression ameliorates cardiac remodeling of mouse following myocardial infarction via CDK4/pRb pathway.
Shi J, Sun J, Liu L, Shan T, Meng H, Yang T, Wang S, Wei T, Chen B, Ma Y, Wang Q, Wang H, Liu J, Wang L
Biochemical and biophysical research communications 2022 Mar 5;595:62-68
Biochemical and biophysical research communications 2022 Mar 5;595:62-68
Green tea peptides ameliorate diabetic nephropathy by inhibiting the TGF-β/Smad signaling pathway in mice.
Chen X, Sun L, Li D, Lai X, Wen S, Chen R, Zhang Z, Li Q, Sun S
Food & function 2022 Mar 21;13(6):3258-3270
Food & function 2022 Mar 21;13(6):3258-3270
Deactivation of AKT/GSK-3β-mediated Wnt/β-catenin pathway by silencing of KIF26B weakens the malignant behaviors of non-small cell lung cancer.
Chen N, Wu Q, Zhang G, Fu J, Geng Q, Zhang Y
Tissue & cell 2022 Jun;76:101750
Tissue & cell 2022 Jun;76:101750
Targeting RPL23 restores chemosensitivity of cisplatin-resistant ovarian carcinoma by inhibiting EMT.
Liu Y, Lai S, He J, Wan J, Fu F, Jinlong Y
Cytotechnology 2022 Jun;74(3):421-432
Cytotechnology 2022 Jun;74(3):421-432
Effects of titanium dioxide microparticles and nanoparticles on cytoskeletal organization, cell adhesion, migration, and proliferation in human gingival fibroblasts in the presence of lipopolysaccharide.
Li L, Sun W, Yu J, Lei W, Zeng H, Shi B
Journal of periodontal research 2022 Jun;57(3):644-659
Journal of periodontal research 2022 Jun;57(3):644-659
Inhibition of FAM83D displays antitumor effects in glioblastoma via down-regulation of the AKT/Wnt/β-catenin pathway.
Wang J, Quan Y, Lv J, Gong S, Ren P
Environmental toxicology 2022 Jun;37(6):1343-1356
Environmental toxicology 2022 Jun;37(6):1343-1356
Lysyl oxidase-like 2 inhibitor rescues D-galactose-induced skeletal muscle fibrosis.
Wu Y, Wu Y, Yang Y, Yu J, Wu J, Liao Z, Guo A, Sun Y, Zhao Y, Chen J, Xiao Q
Aging cell 2022 Jul;21(7):e13659
Aging cell 2022 Jul;21(7):e13659
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
Zhou Q, Gong J, Bi J, Yang X, Zhang L, Lu C, Li L, Chen M, Cai J, Yang R, Li X, Li Z, Wang X
The Journal of investigative dermatology 2022 Jul;142(7):2003-2013.e5
The Journal of investigative dermatology 2022 Jul;142(7):2003-2013.e5
SND1 acts as a functional target of miR-330-5p involved in modulating the proliferation, apoptosis and invasion of colorectal cancer cells.
Deng J, Liu S, Zhao L, Li Y, Shi J, Zhang H, Zhao Y, Han L, Wang H, Yan Y, Zhao H, Zou F
Biochemical and biophysical research communications 2022 Jul 30;615:116-122
Biochemical and biophysical research communications 2022 Jul 30;615:116-122
The presence of living endometrial cells in ovarian endometriotic cyst fluid may contribute to the recurrence of endometriosis after surgical excision of endometriomas.
Xu X, Chen Y, Yu Q, Wang J, Xu P, Zhu L, Xu Q, Zhang J, Cui S, Yu K, Li T, Guo X, Zhang X
Journal of ovarian research 2022 Jul 30;15(1):89
Journal of ovarian research 2022 Jul 30;15(1):89
HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance.
Xie Y, Shi Z, Qian Y, Jiang C, Liu W, Liu B, Jiang B
Cancers 2022 Jul 23;14(15)
Cancers 2022 Jul 23;14(15)
Melatonin and verteporfin synergistically suppress the growth and stemness of head and neck squamous cell carcinoma through the regulation of mitochondrial dynamics.
Shin YY, Seo Y, Oh SJ, Ahn JS, Song MH, Kang MJ, Oh JM, Lee D, Kim YH, Sung ES, Kim HS
Journal of pineal research 2022 Jan;72(1):e12779
Journal of pineal research 2022 Jan;72(1):e12779
HSP90AB1 Promotes the Proliferation, Migration, and Glycolysis of Head and Neck Squamous Cell Carcinoma.
Zhang H, Yin X, Zhang X, Zhou M, Xu W, Wei Z, Song C, Han S, Han W
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221118202
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221118202
Kinesin family member 23 exerts a protumor function in breast cancer via stimulation of the Wnt/β-catenin pathway.
He X, Wang J, Zhou R, Yu S, Jiang J, Zhou Q
Toxicology and applied pharmacology 2022 Jan 15;435:115834
Toxicology and applied pharmacology 2022 Jan 15;435:115834
Nc886 promotes renal cancer cell drug-resistance by enhancing EMT through Rock2 phosphorylation-mediated β-catenin nuclear translocation.
Gao W, Zhang S, Guorong L, Liu Q, Zhu A, Gui F, Zou Y, Wu Y, Luo Y, Hong Z
Cell cycle (Georgetown, Tex.) 2022 Feb;21(4):340-351
Cell cycle (Georgetown, Tex.) 2022 Feb;21(4):340-351
Mesenchyme homeobox 2 has a cancer-inhibiting function in breast carcinoma via affection of the PI3K/AKT/mTOR and ERK1/2 pathways.
Cai Y, Liu Y, Sun Y, Ren Y
Biochemical and biophysical research communications 2022 Feb 19;593:20-27
Biochemical and biophysical research communications 2022 Feb 19;593:20-27
Activation of GRP78 ATPase suppresses A549 lung cancer cell migration by promoting ITGB4 degradation.
Ning J, Cui X, Li N, Li N, Zhao B, Miao J, Lin Z
Cell adhesion & migration 2022 Dec;16(1):107-114
Cell adhesion & migration 2022 Dec;16(1):107-114
Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis.
Sinha T, Ikelle L, Makia MS, Crane R, Zhao X, Kakakhel M, Al-Ubaidi MR, Naash MI
Redox biology 2022 Aug;54:102375
Redox biology 2022 Aug;54:102375
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Peng T, He Y, Wang T, Yu J, Ma X, Zhou Z, Sheng Y, Li L, Peng H, Li S, Zou J, Yuan Y, Zhao Y, Shi H, Li F, Liu W, Hu K, Lu X, Zhang G, Wang F
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
Müller Glia maintain their regenerative potential despite degeneration in the aged zebrafish retina.
Martins RR, Zamzam M, Tracey-White D, Moosajee M, Thummel R, Henriques CM, MacDonald RB
Aging cell 2022 Apr;21(4):e13597
Aging cell 2022 Apr;21(4):e13597
The interferon regulatory factor 6 promotes cisplatin sensitivity in colorectal cancer.
Tan L, Qu W, Wu D, Liu M, Ai Q, Hu H, Wang Q, Chen W, Zhou H
Bioengineered 2022 Apr;13(4):10504-10517
Bioengineered 2022 Apr;13(4):10504-10517
HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis.
Qin T, Xiao Y, Qian W, Wang X, Gong M, Wang Q, An R, Han L, Duan W, Ma Q, Wang Z
Cell death & disease 2022 Apr 21;13(4):387
Cell death & disease 2022 Apr 21;13(4):387
A mesenchymal to epithelial switch in Fgf10 expression specifies an evolutionary-conserved population of ionocytes in salivary glands.
Mauduit O, Aure MH, Delcroix V, Basova L, Srivastava A, Umazume T, Mays JW, Bellusci S, Tucker AS, Hajihosseini MK, Hoffman MP, Makarenkova HP
Cell reports 2022 Apr 12;39(2):110663
Cell reports 2022 Apr 12;39(2):110663
Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.
Xia W, Liu Y, Cheng T, Xu T, Dong M, Hu X
Frontiers in cell and developmental biology 2021;9:628573
Frontiers in cell and developmental biology 2021;9:628573
Qingjie Fuzheng Granule Inhibits EMT and Induces Autophagy in Colorectal Cancer via mTOR Signaling Pathways.
Zhu X, Chen Y, Lin M, Huang B, Lin J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9950499
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9950499
Ginsenoside CK Inhibits TGF-β-Induced Epithelial-Mesenchymal Transition in A549 Cell via SIRT1.
Sun M, Zhuang X, Lv G, Lin Z, Huang X, Zhao J, Lin H, Wang Y
BioMed research international 2021;2021:9140191
BioMed research international 2021;2021:9140191
KMT5A downregulation participated in High Glucose-mediated EndMT via Upregulation of ENO1 Expression in Diabetic Nephropathy.
Lu L, Li X, Zhong Z, Zhou W, Zhou D, Zhu M, Miao C
International journal of biological sciences 2021;17(15):4093-4107
International journal of biological sciences 2021;17(15):4093-4107
P68 RNA Helicase facilitates Breast Cancer progression by promoting Proliferation and Migration via PDGFR-β/AR axis.
Panchbhai N, Turaga RC, Sharma M, Satyanarayana G, Liu ZR
Journal of Cancer 2021;12(21):6543-6552
Journal of Cancer 2021;12(21):6543-6552
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Tong X, Zhang S, Wang D, Zhang L, Huang J, Zhang T, Fan H
Frontiers in pharmacology 2021;12:709819
Frontiers in pharmacology 2021;12:709819
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation.
Aihaiti Y, Song Cai Y, Tuerhong X, Ni Yang Y, Ma Y, Shi Zheng H, Xu K, Xu P
Frontiers in pharmacology 2021;12:672054
Frontiers in pharmacology 2021;12:672054
Sorafenib derivatives-functionalized gold nanoparticles confer protection against tumor angiogenesis and proliferation via suppression of EGFR and VEGFR-2.
Huang W, Xing Y, Zhu L, Zhuo J, Cai M
Experimental cell research 2021 Sep 1;406(1):112633
Experimental cell research 2021 Sep 1;406(1):112633
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Shao S, Qu Z, Liang Y, Xu Y, Zhou D, Li D, Zhang Y, Yin S
International immunopharmacology 2021 Oct;99:107936
International immunopharmacology 2021 Oct;99:107936
Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-AKT signaling pathway as revealed by network pharmacology and in vitro experimental verification.
Wang Y, Chu F, Lin J, Li Y, Johnson N, Zhang J, Gai C, Su Z, Cheng H, Wang L, Ding X
Journal of ethnopharmacology 2021 Oct 28;279:114399
Journal of ethnopharmacology 2021 Oct 28;279:114399
miR-30b-5p inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting GALNT7 via the EGFR/PI3K/AKT pathway.
Wang Y, Wang C, Fu Z, Zhang S, Chen J
Cancer cell international 2021 Nov 24;21(1):618
Cancer cell international 2021 Nov 24;21(1):618
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells.
Zhang N, Hua X, Tu H, Li J, Zhang Z, Max C
Cancer letters 2021 Nov 1;520:400-408
Cancer letters 2021 Nov 1;520:400-408
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.
Xia Y, Chen J, Liu G, Huang W, Wei X, Wei Z, He Y
Chemico-biological interactions 2021 May 25;341:109446
Chemico-biological interactions 2021 May 25;341:109446
CCL21 activation of the MALAT1/SRSF1/mTOR axis underpins the development of gastric carcinoma.
Fu Q, Tan X, Tang H, Liu J
Journal of translational medicine 2021 May 17;19(1):210
Journal of translational medicine 2021 May 17;19(1):210
Trim47 overexpression correlates with poor prognosis in gastric cancer.
Xia Y, Wei Z, Huang W, Wei X, He Y
Neoplasma 2021 Mar;68(2):307-316
Neoplasma 2021 Mar;68(2):307-316
Bone marrow stem cells secretome accelerates simulated birth trauma-induced stress urinary incontinence recovery in rats.
Jiang M, Liu J, Liu W, Zhu X, Bano Y, Liao H, Li H, Jiang HH
Aging 2021 Mar 31;13(7):10517-10534
Aging 2021 Mar 31;13(7):10517-10534
Long non‑coding RNA MIR4435‑2HG promotes the progression of head and neck squamous cell carcinoma by regulating the miR‑383‑5p/RBM3 axis.
Wang S, Chen X, Qiao T
Oncology reports 2021 Jun;45(6)
Oncology reports 2021 Jun;45(6)
SOD3 deficiency induces liver fibrosis by promoting hepatic stellate cell activation and epithelial-mesenchymal transition.
Sun YL, Bai T, Zhou L, Zhu RT, Wang WJ, Liang RP, Li J, Zhang CX, Gou JJ
Journal of cellular physiology 2021 Jun;236(6):4313-4329
Journal of cellular physiology 2021 Jun;236(6):4313-4329
LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition.
Xu M, Lin B, Zheng D, Wen J, Hu W, Li C, Zhang X, Zhang X, Qu J
Oncology letters 2021 Jun;21(6):442
Oncology letters 2021 Jun;21(6):442
In Silico, In Vitro, and In Vivo Analysis Identifies Endometrial Circadian Clock Genes in Recurrent Implantation Failure.
Zhai J, Li S, Hu J, Gao M, Sun Y, Chen ZJ, Giudice LC, Du Y
The Journal of clinical endocrinology and metabolism 2021 Jun 16;106(7):2077-2091
The Journal of clinical endocrinology and metabolism 2021 Jun 16;106(7):2077-2091
YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.
Li Y, Zhu X, Yang M, Wang Y, Li J, Fang J, Guo W, Ma S, Guan F
Molecular carcinogenesis 2021 Jul;60(7):440-454
Molecular carcinogenesis 2021 Jul;60(7):440-454
Overexpression of SERPINA3 promotes tumor invasion and migration, epithelial-mesenchymal-transition in triple-negative breast cancer cells.
Zhang Y, Tian J, Qu C, Peng Y, Lei J, Li K, Zong B, Sun L, Liu S
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):859-873
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):859-873
LncRNA LPAL2/miR-1287-5p/EGFR Axis Modulates TED-Derived Orbital Fibroblast Activation Through Cell Adhesion Factors.
Wang N, Hou SY, Qi X, Deng M, Cao JM, Tong BD, Xiong W
The Journal of clinical endocrinology and metabolism 2021 Jul 13;106(8):e2866-e2886
The Journal of clinical endocrinology and metabolism 2021 Jul 13;106(8):e2866-e2886
Parthenolide inhibits the tumor characteristics of renal cell carcinoma.
Liu D, Han Y, Liu L, Ren X, Zhang H, Fan S, Qin T, Li L
International journal of oncology 2021 Jan;58(1):100-110
International journal of oncology 2021 Jan;58(1):100-110
The long intergenic noncoding RNA GAS5 reduces cisplatin-resistance in non-small cell lung cancer through the miR-217/LHPP axis.
Yang X, Meng L, Zhong Y, Hu F, Wang L, Wang M
Aging 2021 Jan 8;13(2):2864-2884
Aging 2021 Jan 8;13(2):2864-2884
LINC01116 promotes proliferation and migration of endometrial stromal cells by targeting FOXP1 via sponging miR-9-5p in endometriosis.
Cui L, Chen S, Wang D, Yang Q
Journal of cellular and molecular medicine 2021 Feb;25(4):2000-2012
Journal of cellular and molecular medicine 2021 Feb;25(4):2000-2012
F-Box protein 4 inhibits progression of papillary thyroid cancer.
Xu M, Wang Y, Chen M, Hu H, Xia T, Deng D
Steroids 2021 Feb;166:108773
Steroids 2021 Feb;166:108773
miR-184 targets TP63 to block idiopathic pulmonary fibrosis by inhibiting proliferation and epithelial-mesenchymal transition of airway epithelial cells.
Li J, Pan C, Tang C, Tan W, Zhang W, Guan J
Laboratory investigation; a journal of technical methods and pathology 2021 Feb;101(2):142-154
Laboratory investigation; a journal of technical methods and pathology 2021 Feb;101(2):142-154
Pyrvinium pamoate inhibits cell proliferation through ROS-mediated AKT-dependent signaling pathway in colorectal cancer.
Zheng W, Hu J, Lv Y, Bai B, Shan L, Chen K, Dai S, Zhu H
Medical oncology (Northwood, London, England) 2021 Feb 8;38(2):21
Medical oncology (Northwood, London, England) 2021 Feb 8;38(2):21
CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer.
Fan Y, Wang J, Jin W, Sun Y, Xu Y, Wang Y, Liang X, Su D
Molecular cancer 2021 Feb 2;20(1):25
Molecular cancer 2021 Feb 2;20(1):25
Role of SIK1 in the transition of acute kidney injury into chronic kidney disease.
Hu J, Qiao J, Yu Q, Liu B, Zhen J, Liu Y, Ma Q, Li Y, Wang Q, Wang C, Lv Z
Journal of translational medicine 2021 Feb 15;19(1):69
Journal of translational medicine 2021 Feb 15;19(1):69
Epstein-Barr virus microRNA BART10-3p promotes dedifferentiation and proliferation of nasopharyngeal carcinoma by targeting ALK7.
Luo WJ, He SW, Zou WQ, Zhao Y, He QM, Yang XJ, Guo R, Mao YP
Experimental biology and medicine (Maywood, N.J.) 2021 Dec;246(24):2618-2629
Experimental biology and medicine (Maywood, N.J.) 2021 Dec;246(24):2618-2629
EPB41L5 promotes EMT through the ERK/p38 MAPK signaling pathway in esophageal squamous cell carcinoma.
Bao S, Ji Z, Shi M, Liu X
Pathology, research and practice 2021 Dec;228:153682
Pathology, research and practice 2021 Dec;228:153682
MicroRNA-4423-3p inhibits proliferation of fibroblast-like synoviocytes by targeting matrix metalloproteinase 13 in rheumatoid arthritis.
Xu W, Ye L, Wu H
Bioengineered 2021 Dec;12(2):9411-9423
Bioengineered 2021 Dec;12(2):9411-9423
Knockdown hsa_circ_0063526 inhibits endometriosis progression via regulating the miR-141-5p / EMT axis and downregulating estrogen receptors.
Wei Z, Hu Y, He X, Zhang M, Zhang X, Wang Y, Fang X, Li L
Aging 2021 Dec 30;13(24):26095-26117
Aging 2021 Dec 30;13(24):26095-26117
A reciprocal feedback of miR-548ac/YB-1/Snail induces EndMT of HUVECs during acidity microenvironment.
Chen J, Han S, Chen J, Hu P, Zeng Z, Hu Y, Xiong H, Ke Z, Zhang Y, Xu F, Zhao G
Cancer cell international 2021 Dec 20;21(1):692
Cancer cell international 2021 Dec 20;21(1):692
USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation.
Wu X, Wang H, Zhu D, Chai Y, Wang J, Dai W, Xiao Y, Tang W, Li J, Hong L, Pei M, Zhang J, Lin Z, Wang J, Li A, Liu S
Cell death & disease 2021 Dec 20;13(1):10
Cell death & disease 2021 Dec 20;13(1):10
High throughput proteomic and metabolic profiling identified target correction of metabolic abnormalities as a novel therapeutic approach in head and neck paraganglioma.
Wang Z, Chen H, Xue L, He W, Shu W, Wu H, Wang Z
Translational oncology 2021 Aug;14(8):101146
Translational oncology 2021 Aug;14(8):101146
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
Zhao Y, He L, Wang T, Zhu L, Yan N
Metabolites 2021 Aug 23;11(8)
Metabolites 2021 Aug 23;11(8)
LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.
Guan Y, Li Y, Yang QB, Yu J, Qiao H
Annals of translational medicine 2021 Apr;9(8):664
Annals of translational medicine 2021 Apr;9(8):664
DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway.
Feng J, Li C, Xu R, Li Y, Hou Q, Feng R, Wang S, Zhang L, Li C
Oxidative medicine and cellular longevity 2020;2020:9762390
Oxidative medicine and cellular longevity 2020;2020:9762390
miR-93-5p enhances migration and invasion by targeting RGMB in squamous cell carcinoma of the head and neck.
Zhang S, He Y, Liu C, Li G, Lu S, Jing Q, Chen X, Ma H, Zhang D, Wang Y, Huang D, Tan P, Chen J, Zhang X, Liu Y, Qiu Y
Journal of Cancer 2020;11(13):3871-3881
Journal of Cancer 2020;11(13):3871-3881
Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling.
Wang N, Muhetaer G, Zhang X, Yang B, Wang C, Zhang Y, Wang X, Zhang J, Wang S, Zheng Y, Zhang F, Wang Z
Frontiers in pharmacology 2020;11:591400
Frontiers in pharmacology 2020;11:591400
Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling.
Guo W, Zhang Z, Li G, Lai X, Gu R, Xu W, Chen H, Xing Z, Chen L, Qian J, Xu S, Zeng F, Deng F
Frontiers in oncology 2020;10:544288
Frontiers in oncology 2020;10:544288
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
Zheng T, Chen K, Zhang X, Feng H, Shi Y, Liu L, Zhang J, Chen Y
Aging 2020 Sep 8;12(18):18649-18659
Aging 2020 Sep 8;12(18):18649-18659
The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway.
Xu Z, Feng J, Li Y, Guan D, Chen H, Zhai X, Zhang L, Li C, Li C
Chemico-biological interactions 2020 Sep 1;328:109196
Chemico-biological interactions 2020 Sep 1;328:109196
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Wei W, Ma XD, Jiang GM, Shi B, Zhong W, Sun CL, Zhao L, Hou YJ, Wang H
Oncology research 2020 Sep 1;28(4):423-438
Oncology research 2020 Sep 1;28(4):423-438
Emodin inhibiting neutrophil elastase-induced epithelial-mesenchymal transition through Notch1 signalling in alveolar epithelial cells.
Zhou L, Gao R, Hong H, Li X, Yang J, Shen W, Wang Z, Yang J
Journal of cellular and molecular medicine 2020 Oct;24(20):11998-12007
Journal of cellular and molecular medicine 2020 Oct;24(20):11998-12007
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Zhang J, Chen Y, Lin J, Jia R, An T, Dong T, Zhang Y, Yang X
DNA and cell biology 2020 Mar;39(3):355-367
DNA and cell biology 2020 Mar;39(3):355-367
HOXD9 promote epithelial-mesenchymal transition and metastasis in colorectal carcinoma.
Liu M, Xiao Y, Tang W, Li J, Hong L, Dai W, Zhang W, Peng Y, Wu X, Wang J, Chen Y, Bai Y, Lin J, Yang Q, Wang Y, Lin Z, Liu S, Xiong J, Wang J, Xiang L
Cancer medicine 2020 Jun;9(11):3932-3943
Cancer medicine 2020 Jun;9(11):3932-3943
MicroRNA‑500a‑5p inhibits colorectal cancer cell invasion and epithelial‑mesenchymal transition.
Tang W, Hong L, Dai W, Li J, Zhu H, Lin J, Yang Q, Wang Y, Lin Z, Liu M, Xiao Y, Zhang Y, Wu X, Wang J, Chen Y, Hu H, Liu S, Wang J, Xiang L
International journal of oncology 2020 Jun;56(6):1499-1508
International journal of oncology 2020 Jun;56(6):1499-1508
miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1.
Chen S, Luo Y, Cui L, Yang Q
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1740-1753
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1740-1753
The LncRNA H19/miR-1-3p/CCL2 axis modulates lipopolysaccharide (LPS) stimulation-induced normal human astrocyte proliferation and activation.
Li P, Li Y, Dai Y, Wang B, Li L, Jiang B, Wu P, Xu J
Cytokine 2020 Jul;131:155106
Cytokine 2020 Jul;131:155106
CircATRNL1 promotes epithelial-mesenchymal transition in endometriosis by upregulating Yes-associated protein 1 in vitro.
Wang D, Luo Y, Wang G, Yang Q
Cell death & disease 2020 Jul 29;11(7):594
Cell death & disease 2020 Jul 29;11(7):594
A combination of Citrus reticulata peel and black tea inhibits migration and invasion of liver cancer via PI3K/AKT and MMPs signaling pathway.
Wen S, Sun L, An R, Zhang W, Xiang L, Li Q, Lai X, Huo M, Li D, Sun S
Molecular biology reports 2020 Jan;47(1):507-519
Molecular biology reports 2020 Jan;47(1):507-519
Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells.
Wu Y, Zhao Y, He X, He Z, Wang T, Wan L, Chen L, Yan N
Molecular medicine reports 2020 Jan;21(1):249-257
Molecular medicine reports 2020 Jan;21(1):249-257
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Gong C, Hu X, Xu Y, Yang J, Zong L, Wang C, Zhu J, Li Z, Lu D
Anti-cancer drugs 2020 Feb;31(2):141-149
Anti-cancer drugs 2020 Feb;31(2):141-149
miR-30e-5p represses angiogenesis and metastasis by directly targeting AEG-1 in squamous cell carcinoma of the head and neck.
Zhang S, Li G, Liu C, Lu S, Jing Q, Chen X, Zheng H, Ma H, Zhang D, Ren S, Shen Z, Wang Y, Lu Z, Huang D, Tan P, Chen J, Zhang X, Qiu Y, Liu Y
Cancer science 2020 Feb;111(2):356-368
Cancer science 2020 Feb;111(2):356-368
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.
Ayanlaja AA, Ji G, Wang J, Gao Y, Cheng B, Kanwore K, Zhang L, Xiong Y, Kambey PA, Gao D
Cell communication and signaling : CCS 2020 Feb 12;18(1):24
Cell communication and signaling : CCS 2020 Feb 12;18(1):24
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
Wang W, Chen H, Gao W, Wang S, Wu K, Lu C, Luo X, Li L, Yu C
Oncology reports 2020 Aug;44(2):637-649
Oncology reports 2020 Aug;44(2):637-649
Antiarthritic Effects of a Root Extract from Harpagophytum procumbens DC: Novel Insights into the Molecular Mechanisms and Possible Bioactive Phytochemicals.
Mariano A, Di Sotto A, Leopizzi M, Garzoli S, Di Maio V, Gullì M, Dalla Vedova P, Ammendola S, Scotto d'Abusco A
Nutrients 2020 Aug 23;12(9)
Nutrients 2020 Aug 23;12(9)
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Guo Y, Fan Y, Pei X
Cancer medicine 2020 Apr;9(7):2564-2578
Cancer medicine 2020 Apr;9(7):2564-2578
Ferritinophagic Flux Activation in CT26 Cells Contributed to EMT Inhibition Induced by a Novel Iron Chelator, DpdtpA.
Sun Y, Li C, Feng J, Li Y, Zhai X, Zhang L, Li C
Oxidative medicine and cellular longevity 2019;2019:8753413
Oxidative medicine and cellular longevity 2019;2019:8753413
Electrical Stimulation Activates Fibroblasts through the Elevation of Intracellular Free Ca(2+): Potential Mechanism of Pelvic Electrical Stimulation Therapy.
Li S, Lu D, Tang J, Min J, Hu M, Li Y, Liu Y, Wang L, Liu C, Hong L
BioMed research international 2019;2019:7387803
BioMed research international 2019;2019:7387803
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Yang Z, Yu W, Huang R, Ye M, Min Z
Cancer cell international 2019;19:17
Cancer cell international 2019;19:17
PRR14 overexpression promotes cell growth, epithelial to mesenchymal transition and metastasis of colon cancer via the AKT pathway.
Li F, Zhang C, Fu L
PloS one 2019;14(10):e0218839
PloS one 2019;14(10):e0218839
VASN promotes YAP/TAZ and EMT pathway in thyroid carcinogenesis in vitro.
Bhandari A, Guan Y, Xia E, Huang Q, Chen Y
American journal of translational research 2019;11(6):3589-3599
American journal of translational research 2019;11(6):3589-3599
Interactome of the Autoimmune Risk Protein ANKRD55.
Ugidos N, Mena J, Baquero S, Alloza I, Azkargorta M, Elortza F, Vandenbroeck K
Frontiers in immunology 2019;10:2067
Frontiers in immunology 2019;10:2067
Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression.
Li JM, Jiang GM, Zhao L, Yang F, Yuan WQ, Wang H, Luo YQ
Oncology reports 2019 Nov;42(5):1725-1734
Oncology reports 2019 Nov;42(5):1725-1734
The contrary functions of lncRNA HOTAIR/miR-17-5p/PTEN axis and Shenqifuzheng injection on chemosensitivity of gastric cancer cells.
Jia J, Zhan D, Li J, Li Z, Li H, Qian J
Journal of cellular and molecular medicine 2019 Jan;23(1):656-669
Journal of cellular and molecular medicine 2019 Jan;23(1):656-669
Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression.
Chen Y, Wang D, Peng H, Chen X, Han X, Yu J, Wang W, Liang L, Liu Z, Zheng Y, Hu J, Yang L, Li J, Zhou H, Cui X, Li F
Molecular cancer 2019 Jan 4;18(1):1
Molecular cancer 2019 Jan 4;18(1):1
Downregulation of MUTYH contributes to cisplatin‑resistance of esophageal squamous cell carcinoma cells by promoting Twist‑mediated EMT.
Guo Y, Jia Y, Wang S, Liu N, Gao D, Zhang L, Lin Z, Wang S, Kong F, Peng C, Liu Y
Oncology reports 2019 Dec;42(6):2716-2727
Oncology reports 2019 Dec;42(6):2716-2727
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, Qian M, Guo J, Xu J, Cao L, Chin YE, Coppé JP, Lam EW, Campisi J, Sun Y
Aging cell 2019 Dec;18(6):e13027
Aging cell 2019 Dec;18(6):e13027
NAD(+) repletion inhibits the endothelial-to-mesenchymal transition induced by TGF-β in endothelial cells through improving mitochondrial unfolded protein response.
Zhang M, Weng H, Zheng J
The international journal of biochemistry & cell biology 2019 Dec;117:105635
The international journal of biochemistry & cell biology 2019 Dec;117:105635
RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.
Li Q, Lai Q, He C, Fang Y, Yan Q, Zhang Y, Wang X, Gu C, Wang Y, Ye L, Han L, Lin X, Chen J, Cai J, Li A, Liu S
Journal of experimental & clinical cancer research : CR 2019 Aug 1;38(1):334
Journal of experimental & clinical cancer research : CR 2019 Aug 1;38(1):334
Resistin-Inhibited Neural Stem Cell-Derived Astrocyte Differentiation Contributes to Permeability Destruction of the Blood-Brain Barrier.
Xiaoying L, Li T, Yu S, Jiusheng J, Jilin Z, Jiayi W, Dongxin L, Wengang F, Xinyue Z, Hao Y, Yuhua C, Deshu S
Neurochemical research 2019 Apr;44(4):905-916
Neurochemical research 2019 Apr;44(4):905-916
Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.
Gou Y, Li X, Li P, Zhang H, Xu T, Wang H, Wang B, Ma X, Jiang X, Zhang Z
Human reproduction (Oxford, England) 2019 Apr 1;34(4):646-658
Human reproduction (Oxford, England) 2019 Apr 1;34(4):646-658
MiR-876-5p modulates head and neck squamous cell carcinoma metastasis and invasion by targeting vimentin.
Dong Y, Zheng Y, Wang C, Ding X, Du Y, Liu L, Zhang W, Zhang W, Zhong Y, Wu Y, Song X
Cancer cell international 2018;18:121
Cancer cell international 2018;18:121
Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro.
Zhao L, Xu Y, Tao L, Yang Y, Shen X, Li L, Luo P
Medical science monitor : international medical journal of experimental and clinical research 2018 Sep 9;24:6280-6288
Medical science monitor : international medical journal of experimental and clinical research 2018 Sep 9;24:6280-6288
The molecular landscape of synchronous colorectal cancer reveals genetic heterogeneity.
Wang X, Fang H, Cheng Y, Li L, Sun X, Fu T, Huang P, Zhang A, Feng Z, Li C, Huang X, Li G, Du P, Yang H, Fang X, Li F, Gao Q, Liu B
Carcinogenesis 2018 May 3;39(5):708-718
Carcinogenesis 2018 May 3;39(5):708-718
Inhibition of the receptor for advanced glycation promotes proliferation and repair of human periodontal ligament fibroblasts in response to high glucose via the NF-κB signaling pathway.
Zhan D, Guo L, Zheng L
Archives of oral biology 2018 Mar;87:86-93
Archives of oral biology 2018 Mar;87:86-93
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
Wu D, Zhao B, Qi X, Peng F, Fu H, Chi X, Miao QR, Shao S
Cancer letters 2018 Apr 1;418:135-146
Cancer letters 2018 Apr 1;418:135-146
ECM1 promotes migration and invasion of hepatocellular carcinoma by inducing epithelial-mesenchymal transition.
Chen H, Jia W, Li J
World journal of surgical oncology 2016 Jul 27;14(1):195
World journal of surgical oncology 2016 Jul 27;14(1):195
Carbon monoxide inhibits the nuclear-cytoplasmic translocation of HMGB1 in an in vitro oxidative stress injury model of mouse renal tubular epithelial cells.
Jia Y, Wang L, Zhao GY, Wang ZQ, Chen S, Chen G
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2016 Dec;36(6):791-795
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2016 Dec;36(6):791-795
Krüppel-Like Factor 4 Overexpression Initiates a Mesenchymal-to-Epithelial Transition and Redifferentiation of Human Pancreatic Cells following Expansion in Long Term Adherent Culture.
Muir KR, Lima MJ, Docherty HM, McGowan NW, Forbes S, Heremans Y, Forbes SJ, Heimberg H, Casey J, Docherty K
PloS one 2015;10(10):e0140352
PloS one 2015;10(10):e0140352
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 60330-1-Ig( Vimentin Antibody) at dilution of 1:2000
- Validation comment
- WB
