BS7877

antibody from Bioworld Technology, Inc
Targeting: CXXC1 CFP1, CGBP, hCGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1
Provider product page for BS7877
Western blot
Immunocytochemistry
Immunohistochemistry
Chromatin Immunoprecipitation

Antibody data

Product number
BS7877 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CXXC1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CXXC1.
Description
The human genome contains discrete clusters of unmethylated CpG dinucleotides, called CpG islands, which contribute to the modulation of gene expression by binding transcription factors. Human CpG binding protein (CGBP), detected in K562 cells, is a widely expressed member of CpG binding proteins that requires the CpG dinucleotide to bind DNA. CGBP binds specifically to unmethylated CpG motifs and functions as a transcriptional activator. The CXXC domain of CGBP is conserved in DNA methyltransferase, human trithorax, and methyl-CpG binding protein (MBP), and is involved in DNA-binding. CGBP also contains several domains implicated in protein-protein interactions, such as a coiled-coil domain, and two PHD finger domains, the function of which remains to be determined.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CXXC1 protein structure - BS7877 shown in red.