HPA014785

antibody from Atlas Antibodies

Targeting: TRPM1 CSNB1C, LTRPC1, MLSN1

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA014785

Provider

Atlas Antibodies

Product name

Anti-TRPM1

Antibody type

Polyclonal

Antigen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence

Description

Affinity purified using the PrEST antigen as affinity ligand

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

VGGVNQDVEYSSITDQQLTTEWQCQVQKITRSHST
DIPYIVSEAAVQAEHKEQFADMQDEHHVAEAIPRI
PRLSLTITDRNGMENLLSVKPDQTLGFPSLRSKSL
HGHPRNVKSIQGKL


Isotype

IgG

Vial size

100μl

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References

Submitted references

Identification and characterization of novel TRPM1 autoantibodies from serum of patients with melanoma-associated retinopathy

Stieger K, Varin J, Reynolds M, Bouzidi N, Tick S, Wohlschlegel J, Becquart O, Michiels C, Dereure O, Duvoisin R, Morgans C, Sahel J, Samaran Q, Guillot B, Pulido J, Audo I, Zeitz C
PLOS ONE 2020;15(4):e0231750

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Alterations in Kainate Receptor and TRPM1 Localization in Bipolar Cells after Retinal Photoreceptor Degeneration

Gayet-Primo J, Puthussery T
Frontiers in Cellular Neuroscience 2015;9

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Serum TRPM1 Autoantibodies from Melanoma Associated Retinopathy Patients Enter Retinal ON-Bipolar Cells and Attenuate the Electroretinogram in Mice

Fletcher E, Xiong W, Duvoisin R, Adamus G, Jeffrey B, Gellman C, Morgans C
PLoS ONE 2013;8(8):e69506

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Autoantibodies in Melanoma-Associated Retinopathy Target TRPM1 Cation Channels of Retinal ON Bipolar Cells

Dhingra A, Fina M, Neinstein A, Ramsey D, Xu Y, Fishman G, Alexander K, Qian H, Peachey N, Gregg R, Vardi N
The Journal of Neuroscience 2011;31(11):3962-3967