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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- PAB3539 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3539, RRID:AB_1571974
- Product name
- CDH3 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of CDH3.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Novel CDH3 mutations in hypotrichosis with juvenile macular dystrophy.
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.
Indelman M, Eason J, Hummel M, Loza O, Suri M, Leys MJ, Bayne M, Schwartz FL, Sprecher E
Clinical and experimental dermatology 2007 Mar;32(2):191-6
Clinical and experimental dermatology 2007 Mar;32(2):191-6
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.
Paredes J, Albergaria A, Oliveira JT, Jerónimo C, Milanezi F, Schmitt FC
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Aug 15;11(16):5869-77
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Aug 15;11(16):5869-77
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of CDH3 (arrow) using rabbit CDH3 polyclonal antibody (Cat # PAB3539) in K-562 cell line lysates (35 ug/lane). CDH3 (arrow) was detected using the purified polyclonal antibody (1:1000 dilution).
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of CDH3 (arrow) using rabbit CDH3 polyclonal antibody (Cat # PAB3539). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDH3 gene (Lane 2) (Origene Technologies). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDH3 gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human prostate carcinoma tissue reacted with CDH3 polyclonal antibody (Cat # PAB3539) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
