Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11118-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11118-1-AP, RRID:AB_2143740
- Product name
- MEST antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MEST antibody (Cat. #11118-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hydrogen sulfide attenuates atherosclerosis induced by low shear stress by sulfhydrylating endothelium NFIL3 to restrain MEST mediated endothelial mesenchymal transformation.
High estrogen during ovarian stimulation induced loss of maternal imprinted methylation that is essential for placental development via overexpression of TET2 in mouse oocytes.
Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration.
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice.
Increased co-expression of MEST and BRCA1 is associated with worse prognosis and immune infiltration in ovarian cancer.
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
MEST promotes bladder cancer cell proliferation, migration and invasion via STAT3/Twist-1-mediated EMT.
Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds.
Maternal obesity and gestational weight gain are modestly associated with umbilical cord DNA methylation.
DNA methylation-associated repression of MEST/PEG1 expression contributes to the invasion of extravillous trophoblast cells.
Tissue-specific alternative polyadenylation at the imprinted gene Mest regulates allelic usage at Copg2.
Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells.
Zhou K, Luo W, Gui DD, Ren Z, Wei DH, Liu LS, Li GH, Tang ZH, Xiong WH, Hu HJ, Jiang ZS
Nitric oxide : biology and chemistry 2024 Jan 1;142:47-57
Nitric oxide : biology and chemistry 2024 Jan 1;142:47-57
High estrogen during ovarian stimulation induced loss of maternal imprinted methylation that is essential for placental development via overexpression of TET2 in mouse oocytes.
Lu X, Mao J, Qian C, Lei H, Mu F, Sun H, Yan S, Fang Z, Lu J, Xu Q, Dong J, Su D, Wang J, Jin N, Chen S, Wang X
Cell communication and signaling : CCS 2024 Feb 19;22(1):135
Cell communication and signaling : CCS 2024 Feb 19;22(1):135
Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration.
Yang Y, Chu C, Liu L, Wang C, Hu C, Rung S, Man Y, Qu Y
Nature communications 2023 Sep 26;14(1):5995
Nature communications 2023 Sep 26;14(1):5995
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Wang H, Cui X, Wang L, Fan N, Yu M, Qin H, Liu S, Yan Q
Cell death & disease 2023 Oct 6;14(10):651
Cell death & disease 2023 Oct 6;14(10):651
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice.
Jiang PY, Lin S, Liu JR, Liu Y, Zheng LM, Hong Q, Fan YJ, Xu DX, Chen YH
Archives of toxicology 2023 Nov;97(11):2929-2941
Archives of toxicology 2023 Nov;97(11):2929-2941
Increased co-expression of MEST and BRCA1 is associated with worse prognosis and immune infiltration in ovarian cancer.
Zhang J, Yu S, Li Q, Wang Q, Zhang J
Gynecologic oncology 2022 Mar;164(3):566-576
Gynecologic oncology 2022 Mar;164(3):566-576
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
Yang Y, Ren ZZ, Wei WJ, He ZL, Deng YL, Wang Z, Fan YC, Zhou J, Jiang LH
Pharmaceutical biology 2022 Dec;60(1):1566-1577
Pharmaceutical biology 2022 Dec;60(1):1566-1577
MEST promotes bladder cancer cell proliferation, migration and invasion via STAT3/Twist-1-mediated EMT.
Zhao C, Hu X, Tong S, Mo M, He W, Wang L, Li Y
Translational cancer research 2020 Oct;9(10):6178-6188
Translational cancer research 2020 Oct;9(10):6178-6188
Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds.
Guerrero-Juarez CF, Dedhia PH, Jin S, Ruiz-Vega R, Ma D, Liu Y, Yamaga K, Shestova O, Gay DL, Yang Z, Kessenbrock K, Nie Q, Pear WS, Cotsarelis G, Plikus MV
Nature communications 2019 Feb 8;10(1):650
Nature communications 2019 Feb 8;10(1):650
Maternal obesity and gestational weight gain are modestly associated with umbilical cord DNA methylation.
Thakali KM, Faske JB, Ishwar A, Alfaro MP, Cleves MA, Badger TM, Andres A, Shankar K
Placenta 2017 Sep;57:194-203
Placenta 2017 Sep;57:194-203
DNA methylation-associated repression of MEST/PEG1 expression contributes to the invasion of extravillous trophoblast cells.
Peng W, Chen Y, Luo X, Shan N, Lan X, Olson D, Zhang H, Ding YB, Qi HB
Placenta 2016 Oct;46:92-101
Placenta 2016 Oct;46:92-101
Tissue-specific alternative polyadenylation at the imprinted gene Mest regulates allelic usage at Copg2.
MacIsaac JL, Bogutz AB, Morrissy AS, Lefebvre L
Nucleic acids research 2012 Feb;40(4):1523-35
Nucleic acids research 2012 Feb;40(4):1523-35
Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells.
Li H, Takai N, Yuge A, Furukawa Y, Tsuno A, Tsukamoto Y, Kong S, Moriyama M, Narahara H
Cancer letters 2010 Nov 28;297(2):198-206
Cancer letters 2010 Nov 28;297(2):198-206
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 11118-1-AP(MEST antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MEST antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MEST. This antibody recognizes human,mouse,rat antigen. The MEST antibody has been validated for the following applications: ELISA, WB, IHC analysis.