Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 13343-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13343-1-AP, RRID:AB_2206197
- Product name
- TPSAB1 antibody
- Antibody type
- Polyclonal
- Description
- TPSAB1 antibody (Cat. #13343-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mast Cell-Derived CXCL4: A Key Mediator of Ferroptosis and Cardiac Damage in Septic Cardiomyopathy.
Activation of Intestinal Mast Cells Contributes to Gut Damage After Cardiac Arrest in Mice.
Metabolomics combined with molecular docking and dynamics simulation to investigate the mechanism of action of Fibraurea recisa Pierre in the treatment of chronic urticaria.
Dysregulated mast cell activation induced by diabetic milieu exacerbates the progression of diabetic peripheral neuropathy in mice.
Edaravone attenuates cerebral inflammation by inhibiting mast cells degranulation via ROS/STIM1 signaling pathway in HIE model.
Cold-inducible RNA-binding protein promotes gut barrier dysfunction and visceral hypersensitivity via activating mast cells in IBS-D.
Electroacupuncture ameliorates visceral hypersensitivity and negative emotions by regulating paraventricular hypothalamic nucleus and colonic corticotropin-releasing factor signaling.
HucMSC-Ex alleviates DSS-induced colitis in mice by decreasing mast cell activation via the IL-33/ST2 axis.
SYNPO2 promotes the development of BLCA by upregulating the infiltration of resting mast cells and increasing the resistance to immunotherapy.
Palmatine treats urticaria by reducing inflammation and increasing autophagy.
Integrating single-cell RNA sequencing with spatial transcriptomics reveals an immune landscape of human myometrium during labour.
Identification of hub genes and infiltrating immune cells in skeletal muscle in obesity.
An Amide Alkaloid Isolated from Ephedra sinica Ameliorates OVA-Induced Allergic Asthma by Inhibiting Mast Cell Activation and Dendritic Cell Maturation.
Bromodomain-containing protein 9 is a prognostic biomarker associated with immune infiltrates and promotes tumor malignancy through activating notch signaling pathway in negative HIF-2α clear cell renal cell carcinoma.
The release of tryptase from mast cells promote tumor cell metastasis via exosomes.
Wei J, Jiang ZY, Ye LF, Lu HX
Immunity, inflammation and disease 2026 Mar;14(3):e70359
Immunity, inflammation and disease 2026 Mar;14(3):e70359
Activation of Intestinal Mast Cells Contributes to Gut Damage After Cardiac Arrest in Mice.
Dang L, Rehman AU, Zhang J, Zhang R, Yu X, Sheng H, Karhausen J, Yang W
Shock (Augusta, Ga.) 2026 Jan 1;65(1):85-92
Shock (Augusta, Ga.) 2026 Jan 1;65(1):85-92
Metabolomics combined with molecular docking and dynamics simulation to investigate the mechanism of action of Fibraurea recisa Pierre in the treatment of chronic urticaria.
Xiao T, Tao J, Tan J, Zhao Z, Yang L, Zhang C, Duan X
Frontiers in pharmacology 2025;16:1571819
Frontiers in pharmacology 2025;16:1571819
Dysregulated mast cell activation induced by diabetic milieu exacerbates the progression of diabetic peripheral neuropathy in mice.
Yao X, Wang X, Zhang R, Kong L, Fan C, Qian Y
Nature communications 2025 May 5;16(1):4170
Nature communications 2025 May 5;16(1):4170
Edaravone attenuates cerebral inflammation by inhibiting mast cells degranulation via ROS/STIM1 signaling pathway in HIE model.
Ye Q, Lu W, Li T, Li Y, Tang S, Xiao P, Wei T, Zhao J, Wang Z, Huang J
International immunopharmacology 2025 Jun 26;159:114880
International immunopharmacology 2025 Jun 26;159:114880
Cold-inducible RNA-binding protein promotes gut barrier dysfunction and visceral hypersensitivity via activating mast cells in IBS-D.
Wang T, Yang P, Dong S, He X, Dai F, Wang J, Lyu Y, Wu R, Zhang J
International immunopharmacology 2025 Dec 3;166:115640
International immunopharmacology 2025 Dec 3;166:115640
Electroacupuncture ameliorates visceral hypersensitivity and negative emotions by regulating paraventricular hypothalamic nucleus and colonic corticotropin-releasing factor signaling.
Xu JG, Yuan Y, Ma HK, Huang S, Zhu SL, Li TT, Wang XY, Shen GM, Wang H
World journal of psychiatry 2025 Aug 19;15(8):107342
World journal of psychiatry 2025 Aug 19;15(8):107342
HucMSC-Ex alleviates DSS-induced colitis in mice by decreasing mast cell activation via the IL-33/ST2 axis.
Wei Z, Tang X, Yi C, Ocansey DKW, Mao F, Mao Z
American journal of translational research 2024;16(6):2727-2744
American journal of translational research 2024;16(6):2727-2744
SYNPO2 promotes the development of BLCA by upregulating the infiltration of resting mast cells and increasing the resistance to immunotherapy.
Ye G, Tu L, Li Z, Li X, Zheng X, Song Y
Oncology reports 2024 Jan;51(1)
Oncology reports 2024 Jan;51(1)
Palmatine treats urticaria by reducing inflammation and increasing autophagy.
Xiao T, Yu X, Yang L, Duan X
Frontiers in immunology 2023;14:1268467
Frontiers in immunology 2023;14:1268467
Integrating single-cell RNA sequencing with spatial transcriptomics reveals an immune landscape of human myometrium during labour.
Ji K, Chen L, Wang X, Wen B, Yang F, Deng W, Chen Y, Zhang G, Liu H
Clinical and translational medicine 2023 Apr;13(4):e1234
Clinical and translational medicine 2023 Apr;13(4):e1234
Identification of hub genes and infiltrating immune cells in skeletal muscle in obesity.
Jin S, Huang J, Chen K, Wang X
Annals of translational medicine 2022 Oct;10(19):1052
Annals of translational medicine 2022 Oct;10(19):1052
An Amide Alkaloid Isolated from Ephedra sinica Ameliorates OVA-Induced Allergic Asthma by Inhibiting Mast Cell Activation and Dendritic Cell Maturation.
Jia J, Zeng M, Zhu D, Jiao X, Zhang B, Yang R, Feng W, Zheng X
International journal of molecular sciences 2022 Nov 4;23(21)
International journal of molecular sciences 2022 Nov 4;23(21)
Bromodomain-containing protein 9 is a prognostic biomarker associated with immune infiltrates and promotes tumor malignancy through activating notch signaling pathway in negative HIF-2α clear cell renal cell carcinoma.
Lou W, Gao K, Xu C, Li Q
IUBMB life 2021 Nov;73(11):1334-1347
IUBMB life 2021 Nov;73(11):1334-1347
The release of tryptase from mast cells promote tumor cell metastasis via exosomes.
Xiao H, He M, Xie G, Liu Y, Zhao Y, Ye X, Li X, Zhang M
BMC cancer 2019 Oct 29;19(1):1015
BMC cancer 2019 Oct 29;19(1):1015
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 13343-1-AP(TPSAB1 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human appendix using 13343-1-AP(TPSAB1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The TPSAB1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TPSAB1. This antibody recognizes human,mouse,rat antigen. The TPSAB1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.