orb2635078

antibody from Biorbyt
Targeting: SIRT3 SIR2L3
Provider product page for orb2635078
Western blot
ELISA
Immunocytochemistry
Flow cytometry

Antibody data

Product number
orb2635078 - Provider product page
Provider
Biorbyt
Product name
SIRT3 Antibody
Antibody type
Monoclonal
Description
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
PCRP-SIRT3-1C10
Vial size
100 ug
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
SIRT3 protein structure - orb2635078 shown in red.