HPA001768

antibody from Atlas Antibodies

Targeting: MYO1C myr2

Western blot (Data presented on provider website)

Immunohistochemistry (Enhanced validation)

Antibody Data

Product number

HPA001768

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA001768, RRID:AB_1854252

Product name

Anti-MYO1C

Antibody type

Polyclonal

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

GEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDK
SDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGN
IHFAANEESNAQVTTENQLKYLTRLLSVEGSTLRE
ALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVY
SRTFTWLV


Isotype

IgG

Vial size

100 µl

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References

Submitted references

Analysis of an independent tumor suppressor locus telomeric to Tp53 suggested Inpp5k and Myo1c as novel tumor suppressor gene candidates in this region.

Hedberg Oldfors C, Dios DG, Linder A, Visuttijai K, Samuelson E, Karlsson S, Nilsson S, Behboudi A
BMC genetics 2015 Jul 14;16:80

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The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling.

Tiwari A, Jung JJ, Inamdar SM, Nihalani D, Choudhury A
American journal of physiology. Heart and circulatory physiology 2013 Mar 1;304(5):H687-96

Immunohistochemistry

Enhanced validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human lung and skeletal muscle tissues using Anti-MYO1C antibody. Corresponding MYO1C RNA-seq data are presented for the same tissues.

Sample type

HUMAN

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of human lung shows high expression.

Sample type

HUMAN

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of human skeletal muscle shows low expression as expected.

Sample type

HUMAN