FNab04930

antibody from FineTest Biotech

Targeting: MAFB KRML

Western blot

ELISA

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Validation data

Product number: FNab04930 - Provider product page
Provider: FineTest Biotech
Product name: MAFB antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter(By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Reactivity: Human, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: v-maf musculoaponeurotic fibrosarco ma oncogene homolog B(avian)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

MAFB protein structure - FNab04930 shown in red.