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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Chromatin Immunoprecipitation [1]
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- Product number
- HPA005653 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA005653, RRID:AB_1079293
- Product name
- Anti-MAFB
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human MAFB, Gene description: v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B, Alternative Gene Names: KRML, Validated applications: ChIP, IHC, ICC, Uniprot ID: Q9Y5Q3, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Macrophage re-programming by JAK inhibitors relies on MAFB
Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons, and heterogeneity
Inhibition of LXR controls the polarization of human inflammatory macrophages through upregulation of MAFB
MAFB shapes human monocyte–derived macrophage response to SARS-CoV-2 and controls severe COVID-19 biomarker expression
Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs
TLR7 Activation in M-CSF-Dependent Monocyte-Derived Human Macrophages Potentiates Inflammatory Responses and Prompts Neutrophil Recruitment
MafB-dependent neurotransmitter signaling promotes β cell migration in the developing pancreas.
Coordinated glucocorticoid receptor and MAFB action induces tolerogenesis and epigenome remodeling in dendritic cells
Activation of LXR Nuclear Receptors Impairs the Anti-Inflammatory Gene and Functional Profile of M-CSF-Dependent Human Monocyte-Derived Macrophages
Activation of RARα Receptor Attenuates Neuroinflammation After SAH via Promoting M1-to-M2 Phenotypic Polarization of Microglia and Regulating Mafb/Msr1/PI3K-Akt/NF-κB Pathway
Early development of the cochlea of the common marmoset, a non-human primate model.
Expression of Maf family proteins in glutamatergic neurons of the mouse olfactory bulb
Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages
Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis
β-catenin regulates the formation of multiple nephron segments in the mouse kidney
Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function
Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
Origin and Segmental Diversity of Spinal Inhibitory Interneurons
Dynamic Expression of Sox2, Gata3, and Prox1 during Primary Auditory Neuron Development in the Mammalian Cochlea
Neurosensory Differentiation and Innervation Patterning in the Human Fetal Vestibular End Organs between the Gestational Weeks 8–12
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
Single cell dissection of early kidney development: multilineage priming
López-Navarro B, Simón-Fuentes M, Ríos I, Schiaffino M, Sanchez A, Torres-Torresano M, Nieto-Valle A, Castrejón I, Puig-Kröger A
Cellular and Molecular Life Sciences 2024;81(1)
Cellular and Molecular Life Sciences 2024;81(1)
Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons, and heterogeneity
Worthy A, Anderson J, Lane A, Gomez-Perez L, Wang A, Griffith R, Rivard A, Bikoff J, Alvarez F
eLife 2024;13
eLife 2024;13
Inhibition of LXR controls the polarization of human inflammatory macrophages through upregulation of MAFB
de la Aleja A, Herrero C, Torres-Torresano M, Schiaffino M, del Castillo A, Alonso B, Vega M, Puig-Kröger A, Castrillo A, Corbí Á
Cellular and Molecular Life Sciences 2023;80(4)
Cellular and Molecular Life Sciences 2023;80(4)
MAFB shapes human monocyte–derived macrophage response to SARS-CoV-2 and controls severe COVID-19 biomarker expression
Simón-Fuentes M, Ríos I, Herrero C, Lasala F, Labiod N, Luczkowiak J, Roy-Vallejo E, Fernández de Córdoba-Oñate S, Delgado-Wicke P, Bustos M, Fernández-Ruiz E, Colmenares M, Puig-Kröger A, Delgado R, Vega M, Corbí Á, Domínguez-Soto Á
JCI Insight 2023;8(24)
JCI Insight 2023;8(24)
Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs
Knowles S, Stafford A, Zaman T, Angara K, Williams M, Newbern J, Vogt D
Development 2023;150(10)
Development 2023;150(10)
TLR7 Activation in M-CSF-Dependent Monocyte-Derived Human Macrophages Potentiates Inflammatory Responses and Prompts Neutrophil Recruitment
Simón-Fuentes M, Herrero C, Acero-Riaguas L, Nieto C, Lasala F, Labiod N, Luczkowiak J, Alonso B, Delgado R, Colmenares M, Corbí Á, Domínguez-Soto Á
Journal of Innate Immunity 2023;15(1):517-530
Journal of Innate Immunity 2023;15(1):517-530
MafB-dependent neurotransmitter signaling promotes β cell migration in the developing pancreas.
Bsharat S, Monni E, Singh T, Johansson JK, Achanta K, Bertonnier-Brouty L, Schmidt-Christensen A, Holmberg D, Kokaia Z, Prasad RB, Artner I
Development (Cambridge, England) 2023 Mar 15;150(6)
Development (Cambridge, England) 2023 Mar 15;150(6)
Coordinated glucocorticoid receptor and MAFB action induces tolerogenesis and epigenome remodeling in dendritic cells
Morante-Palacios O, Ciudad L, Micheroli R, de la Calle-Fabregat C, Li T, Barbisan G, Houtman M, Edalat S, Frank-Bertoncelj M, Ospelt C, Ballestar E
Nucleic Acids Research 2022;50(1):108-126
Nucleic Acids Research 2022;50(1):108-126
Activation of LXR Nuclear Receptors Impairs the Anti-Inflammatory Gene and Functional Profile of M-CSF-Dependent Human Monocyte-Derived Macrophages
González de la Aleja A, Herrero C, Torres-Torresano M, de la Rosa J, Alonso B, Capa-Sardón E, Muller I, Jansen G, Puig-Kröger A, Vega M, Castrillo A, Corbí Á
Frontiers in Immunology 2022;13
Frontiers in Immunology 2022;13
Activation of RARα Receptor Attenuates Neuroinflammation After SAH via Promoting M1-to-M2 Phenotypic Polarization of Microglia and Regulating Mafb/Msr1/PI3K-Akt/NF-κB Pathway
Tian Y, Liu B, Li Y, Zhang Y, Shao J, Wu P, Xu C, Chen G, Shi H
Frontiers in Immunology 2022;13
Frontiers in Immunology 2022;13
Early development of the cochlea of the common marmoset, a non-human primate model.
Hosoya M, Fujioka M, Okahara J, Yoshimatsu S, Okano H, Ozawa H
Neural development 2022 May 7;17(1):6
Neural development 2022 May 7;17(1):6
Expression of Maf family proteins in glutamatergic neurons of the mouse olfactory bulb
Ito A, Imamura F
Developmental Neurobiology 2021;82(1):77-87
Developmental Neurobiology 2021;82(1):77-87
Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages
Li C, Li X, Bi Z, Sugino K, Wang G, Zhu T, Liu Z
eLife 2020;9
eLife 2020;9
Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis
Dieterich L, Tacconi C, Menzi F, Proulx S, Kapaklikaya K, Hamada M, Takahashi S, Detmar M
Angiogenesis 2020;23(3):411-423
Angiogenesis 2020;23(3):411-423
β-catenin regulates the formation of multiple nephron segments in the mouse kidney
Deacon P, Concodora C, Chung E, Park J
Scientific Reports 2019;9(1)
Scientific Reports 2019;9(1)
Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function
Pai E, Vogt D, Clemente-Perez A, McKinsey G, Cho F, Hu J, Wimer M, Paul A, Fazel Darbandi S, Pla R, Nowakowski T, Goodrich L, Paz J, Rubenstein J
Cell Reports 2019;26(5):1157-1173.e5
Cell Reports 2019;26(5):1157-1173.e5
Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
Aran D, Looney A, Liu L, Wu E, Fong V, Hsu A, Chak S, Naikawadi R, Wolters P, Abate A, Butte A, Bhattacharya M
Nature Immunology 2019;20(2):163-172
Nature Immunology 2019;20(2):163-172
Origin and Segmental Diversity of Spinal Inhibitory Interneurons
Sweeney L, Bikoff J, Gabitto M, Brenner-Morton S, Baek M, Yang J, Tabak E, Dasen J, Kintner C, Jessell T
Neuron 2018;97(2):341-355.e3
Neuron 2018;97(2):341-355.e3
Dynamic Expression of Sox2, Gata3, and Prox1 during Primary Auditory Neuron Development in the Mammalian Cochlea
Bermingham-McDonogh O, Nishimura K, Noda T, Dabdoub A
PLOS ONE 2017;12(1):e0170568
PLOS ONE 2017;12(1):e0170568
Neurosensory Differentiation and Innervation Patterning in the Human Fetal Vestibular End Organs between the Gestational Weeks 8–12
Johnson Chacko L, Pechriggl E, Fritsch H, Rask-Andersen H, Blumer M, Schrott-Fischer A, Glueckert R
Frontiers in Neuroanatomy 2016;10
Frontiers in Neuroanatomy 2016;10
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
Pasquali L, Gaulton K, Rodríguez-Seguí S, Mularoni L, Miguel-Escalada I, Akerman İ, Tena J, Morán I, Gómez-Marín C, van de Bunt M, Ponsa-Cobas J, Castro N, Nammo T, Cebola I, García-Hurtado J, Maestro M, Pattou F, Piemonti L, Berney T, Gloyn A, Ravassard P, Skarmeta J, Müller F, McCarthy M, Ferrer J
Nature Genetics 2014;46(2):136-143
Nature Genetics 2014;46(2):136-143
Single cell dissection of early kidney development: multilineage priming
Brunskill E, Park J, Chung E, Chen F, Magella B, Potter S
Development 2014;141(15):3093-3101
Development 2014;141(15):3093-3101
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line hTCEpi shows localization to nucleus & the Golgi apparatus.
- Sample type
- Human
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- ChIP-Exo-Seq composite graph for Anti-MAFB (HPA005653, Lot 000044811) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.
