Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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Validation data
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- Product number
- HPA001915 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA001915, RRID:AB_1080331
- Product name
- Anti-TOP1MT
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human TOP1MT, Gene description: topoisomerase (DNA) I, mitochondrial, Validated applications: ICC, IHC, Uniprot ID: Q969P6, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Self‐assembly of multi‐component mitochondrial nucleoids via phase separation
Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA
Feric M, Demarest T, Tian J, Croteau D, Bohr V, Misteli T
The EMBO Journal 2021;40(6)
The EMBO Journal 2021;40(6)
Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA
Nicholls T, Nadalutti C, Motori E, Sommerville E, Gorman G, Basu S, Hoberg E, Turnbull D, Chinnery P, Larsson N, Larsson E, Falkenberg M, Taylor R, Griffith J, Gustafsson C
Molecular Cell 2018;69(1):9-23.e6
Molecular Cell 2018;69(1):9-23.e6
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line A-431 shows localization to mitochondria.
- Sample type
- Human