Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 22337-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- TCF4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TCF4 antibody (Cat. #22337-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FHL1 Inhibits the Progression of Colorectal Cancer by Regulating the Wnt/β-Catenin Signaling Pathway.
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma.
Circ_SMAD4 promotes gastric carcinogenesis by activating wnt/β-catenin pathway.
Pygo1 regulates pathological cardiac hypertrophy via a β-catenin-dependent mechanism.
miR-129-5p Inhibits Bone Formation Through TCF4.
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.
Mouse Retinal Cell Atlas: Molecular Identification of over Sixty Amacrine Cell Types.
ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway.
Ursolic acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in non-small-cell lung carcinoma harbouring EGFR T790M mutations.
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
miR-10b promoted melanoma progression through Wnt/β-catenin pathway by repressing ITCH expression.
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Anticancer activity and potential mechanisms of 1C, a ginseng saponin derivative, on prostate cancer cells.
TIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transition.
Tcf4 Controls Neuronal Migration of the Cerebral Cortex through Regulation of Bmp7.
Type I bHLH Proteins Daughterless and Tcf4 Restrict Neurite Branching and Synapse Formation by Repressing Neurexin in Postmitotic Neurons.
Liu Y, Wang C, Cheng P, Zhang S, Zhou W, Xu Y, Xu H, Ji G
Journal of Cancer 2021;12(17):5345-5354
Journal of Cancer 2021;12(17):5345-5354
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
Zeng S, Chen L, Sun Q, Zhao H, Yang H, Ren S, Liu M, Meng X, Xu H
European journal of pharmacology 2021 Sep 5;906:174253
European journal of pharmacology 2021 Sep 5;906:174253
A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma.
Liu T, Hu J, Han B, Tan S, Jia W, Xin Y
Cell death & disease 2021 Oct 16;12(11):952
Cell death & disease 2021 Oct 16;12(11):952
Circ_SMAD4 promotes gastric carcinogenesis by activating wnt/β-catenin pathway.
Wang L, Li B, Yi X, Xiao X, Zheng Q, Ma L
Cell proliferation 2021 Mar;54(3):e12981
Cell proliferation 2021 Mar;54(3):e12981
Pygo1 regulates pathological cardiac hypertrophy via a β-catenin-dependent mechanism.
Lin L, Xu W, Li Y, Zhu P, Yuan W, Liu M, Shi Y, Chen Y, Liang J, Chen J, Yang B, Cai W, Wen Y, Zhu X, Peng X, Zhou Z, Mo X, Wan Y, Yuan H, Li F, Ye X, Jiang Z, Wang Y, Zhuang J, Fan X, Wu X
American journal of physiology. Heart and circulatory physiology 2021 Apr 1;320(4):H1634-H1645
American journal of physiology. Heart and circulatory physiology 2021 Apr 1;320(4):H1634-H1645
miR-129-5p Inhibits Bone Formation Through TCF4.
Yin C, Tian Y, Yu Y, Yang C, Su P, Zhao Y, Wang X, Zhang K, Pei J, Li D, Chen Z, Zhang Y, Miao Z, Qian A
Frontiers in cell and developmental biology 2020;8:600641
Frontiers in cell and developmental biology 2020;8:600641
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/β‑catenin pathway.
Ren Y, Wang Y, Hao S, Yang Y, Xiong W, Qiu L, Tao J, Tang A
Journal of Cancer 2020;11(23):6939-6949
Journal of Cancer 2020;11(23):6939-6949
MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.
Chen T, Lei S, Zeng Z, Pan S, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
International journal of molecular medicine 2020 Mar;45(3):886-896
International journal of molecular medicine 2020 Mar;45(3):886-896
Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.
Chen T, Lei S, Zeng Z, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
Oncology reports 2020 Mar;43(3):930-942
Oncology reports 2020 Mar;43(3):930-942
Mouse Retinal Cell Atlas: Molecular Identification of over Sixty Amacrine Cell Types.
Yan W, Laboulaye MA, Tran NM, Whitney IE, Benhar I, Sanes JR
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Jul 1;40(27):5177-5195
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Jul 1;40(27):5177-5195
ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway.
Xiao H, Cheng Q, Wu X, Tang Y, Liu J, Li X
Cancer management and research 2019;11:8547-8555
Cancer management and research 2019;11:8547-8555
Ursolic acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in non-small-cell lung carcinoma harbouring EGFR T790M mutations.
Yang K, Chen Y, Zhou J, Ma L, Shan Y, Cheng X, Wang Y, Zhang Z, Ji X, Chen L, Dai H, Zhu B, Li C, Tao Z, Hu X, Yin W
British journal of pharmacology 2019 Dec;176(24):4609-4624
British journal of pharmacology 2019 Dec;176(24):4609-4624
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
Yu G, Liu P, Shi Y, Li S, Liu Y, Fan Z, Zhu W
Journal of neurosurgery 2019 Aug 9;:1-9
Journal of neurosurgery 2019 Aug 9;:1-9
miR-10b promoted melanoma progression through Wnt/β-catenin pathway by repressing ITCH expression.
Wang S, Wu Y, Xu Y, Tang X
Gene 2019 Aug 20;710:39-47
Gene 2019 Aug 20;710:39-47
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, Zhang C, Bi Y, Zhang C, Bian H
Chinese medicine 2018;13:17
Chinese medicine 2018;13:17
Anticancer activity and potential mechanisms of 1C, a ginseng saponin derivative, on prostate cancer cells.
Wang X, Su GY, Zhao C, Qu FZ, Wang P, Zhao YQ
Journal of ginseng research 2018 Apr;42(2):133-143
Journal of ginseng research 2018 Apr;42(2):133-143
TIMELESS confers cisplatin resistance in nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway and promoting the epithelial mesenchymal transition.
Liu SL, Lin HX, Lin CY, Sun XQ, Ye LP, Qiu F, Wen W, Hua X, Wu XQ, Li J, Song LB, Guo L
Cancer letters 2017 Aug 28;402:117-130
Cancer letters 2017 Aug 28;402:117-130
Tcf4 Controls Neuronal Migration of the Cerebral Cortex through Regulation of Bmp7.
Chen T, Wu Q, Zhang Y, Lu T, Yue W, Zhang D
Frontiers in molecular neuroscience 2016;9:94
Frontiers in molecular neuroscience 2016;9:94
Type I bHLH Proteins Daughterless and Tcf4 Restrict Neurite Branching and Synapse Formation by Repressing Neurexin in Postmitotic Neurons.
D'Rozario M, Zhang T, Waddell EA, Zhang Y, Sahin C, Sharoni M, Hu T, Nayal M, Kutty K, Liebl F, Hu W, Marenda DR
Cell reports 2016 Apr 12;15(2):386-97
Cell reports 2016 Apr 12;15(2):386-97
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 22337-1-AP( TCF4 Antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TCF4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TCF4. This antibody recognizes human, mouse antigen. The TCF4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.