Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Flow cytometry [1]
- Other assay [1]
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Validation data
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- Product number
- 12-0497-41 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Integrin beta 5 Monoclonal Antibody (KN52), PE, eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: The KN52 antibody reacts with human integrin beta 5, an approximately 100,000 Mr (reduced) and 95,000 Mr (nonreduced) a member of the integrin family. Only a single alpha chain, the alpha v subunit, associates with the integrin beta 5 to form the vitronectin receptor complex. Integrin alpha v/beta 5 complex also binds to the basic domain of Tat (he sequence RKKRRQRRR). The integrin beta 5 is found on carcinoma cell lines, hepatoma and fibroblast cell lines, and is absent from lymphoblastoid cells and platelets.
- Conjugate
- Yellow dye
- Antibody clone number
- KN52
- Concentration
- 5 µL/Test
Submitted references Preexisting Virus-Specific T Lymphocytes-Mediated Enhancement of Adenovirus Infections to Human Blood CD14+ Cells.
Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes.
Laminin 521 maintains differentiation potential of mouse and human satellite cell-derived myoblasts during long-term culture expansion.
Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression.
Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis.
Feng F, Zhao J, Li P, Li R, Chen L, Sun C
Viruses 2019 Feb 13;11(2)
Viruses 2019 Feb 13;11(2)
Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes.
Lopez-Fabuel I, Le Douce J, Logan A, James AM, Bonvento G, Murphy MP, Almeida A, BolaƱos JP
Proceedings of the National Academy of Sciences of the United States of America 2016 Nov 15;113(46):13063-13068
Proceedings of the National Academy of Sciences of the United States of America 2016 Nov 15;113(46):13063-13068
Laminin 521 maintains differentiation potential of mouse and human satellite cell-derived myoblasts during long-term culture expansion.
Penton CM, Badarinarayana V, Prisco J, Powers E, Pincus M, Allen RE, August PR
Skeletal muscle 2016 Dec 13;6(1):44
Skeletal muscle 2016 Dec 13;6(1):44
Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression.
Keasey MP, Kang SS, Lovins C, Hagg T
Cell communication and signaling : CCS 2013 May 21;11:35
Cell communication and signaling : CCS 2013 May 21;11:35
Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis.
Sangaletti S, Di Carlo E, Gariboldi S, Miotti S, Cappetti B, Parenza M, Rumio C, Brekken RA, Chiodoni C, Colombo MP
Cancer research 2008 Nov 1;68(21):9050-9
Cancer research 2008 Nov 1;68(21):9050-9
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Staining of CHO cells with Mouse IgG1 kappa Isotype Control PE (Product # 12-4714-81) (open histogram) or Anti-Integrin beta 5 PE (filled histogram). Total viable cells were used for analysis.
- Conjugate
- Yellow dye
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Conjugate
- Yellow dye