ABIN500712

antibody from antibodies-online

Targeting: SIGIRR IL-1R8, TIR8

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN500712

Provider

antibodies-online

Product name

anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (C-Term) antibody

Antibody type

Polyclonal

Antigen

SIGIRR antibody was raised against a synthetic peptide corresponding to 15 amino acids atthe C-terminus of mouse SIGIRR.

Reactivity

Human, Mouse

Host

Rabbit

Isotype

IgG

Vial size

0.1 mg

Storage

Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.

References

Submitted references

Toll-like receptors.

Takeda K, Kaisho T, Akira S
Annual review of immunology 2003;21:335-76

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SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling.

Wald D, Qin J, Zhao Z, Qian Y, Naramura M, Tian L, Towne J, Sims JE, Stark GR, Li X
Nature immunology 2003 Sep;4(9):920-7

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Innate immune recognition.

Janeway CA Jr, Medzhitov R
Annual review of immunology 2002;20:197-216

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Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily.

Thomassen E, Renshaw BR, Sims JE
Cytokine 1999 Jun;11(6):389-99

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of SIGIRR in A549 cell lysate with AP30779PU-N at (A) 0.5, (B) 1, and (C) 2 ?g/ml.

Immunocytochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Immunocytochemistry of SIGIRR in A549 cells with AP30779PU-N at 10 ?g/ml.