Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA001869 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA001869, RRID:AB_1078818
- Product name
- Anti-FAT1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human FAT1, Gene description: FAT atypical cadherin 1, Alternative Gene Names: CDHF7, CDHR8, FAT, Validated applications: IHC, Uniprot ID: Q14517, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.4 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway
A Soluble Form of the Giant Cadherin Fat1 Is Released from Pancreatic Cancer Cells by ADAM10 Mediated Ectodomain Shedding
Deregulation of the Protocadherin Gene FAT1 Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy
Li Z, Razavi P, Li Q, Toy W, Liu B, Ping C, Hsieh W, Sanchez-Vega F, Brown D, Da Cruz Paula A, Morris L, Selenica P, Eichenberger E, Shen R, Schultz N, Rosen N, Scaltriti M, Brogi E, Baselga J, Reis-Filho J, Chandarlapaty S
Cancer Cell 2018;34(6):893-905.e8
Cancer Cell 2018;34(6):893-905.e8
A Soluble Form of the Giant Cadherin Fat1 Is Released from Pancreatic Cancer Cells by ADAM10 Mediated Ectodomain Shedding
Hoffmann A, Wojtalewicz N, Sadeqzadeh E, Weiß J, Tehrani M, Klein-Scory S, Hahn S, Schmiegel W, Warnken U, Schnölzer M, de Bock C, Thorne R, Schwarte-Waldhoff I
PLoS ONE 2014;9(3):e90461
PLoS ONE 2014;9(3):e90461
Deregulation of the Protocadherin Gene FAT1 Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy
Cox G, Caruso N, Herberth B, Bartoli M, Puppo F, Dumonceaux J, Zimmermann A, Denadai S, Lebossé M, Roche S, Geng L, Magdinier F, Attarian S, Bernard R, Maina F, Levy N, Helmbacher F
PLoS Genetics 2013;9(6):e1003550
PLoS Genetics 2013;9(6):e1003550
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human duodenum and lymph node tissues using HPA001869 antibody. Corresponding FAT1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol