Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 20310-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20310-1-AP, RRID:AB_10699880
- Product name
- DRD5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DRD5 antibody (Cat. #20310-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Kinase Activity Is Not Required for G Protein-Coupled Receptor Kinase 4 Restraining mTOR Signaling during Cilia and Kidney Development.
Gastrointestinal Dopamine in Inflammatory Bowel Diseases: A Systematic Review.
DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization.
Increased AT(1) receptor expression mediates vasoconstriction leading to hypertension in Snx1(-/-) mice.
Activation of dopamine receptor D1 inhibits glioblastoma tumorigenicity by regulating autophagic activity.
Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation.
Development of a PC12 Cell Based Assay for Screening Catechol-O-methyltransferase Inhibitors.
Validation of the targeted metabolomic pathway in the hippocampus and comparative analysis with the prefrontal cortex of social defeat model mice.
Gender-dependent and genotype-sensitive monoaminergic changes induced by polychlorinated biphenyl 153 in the rat brain.
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome.
Vivo-morpholinos induced transient knockdown of physical activity related proteins.
Gerhards J, Maerz LD, Matthees ESF, Donow C, Moepps B, Premont RT, Burkhalter MD, Hoffmann C, Philipp M
Journal of the American Society of Nephrology : JASN 2023 Apr 1;34(4):590-606
Journal of the American Society of Nephrology : JASN 2023 Apr 1;34(4):590-606
Gastrointestinal Dopamine in Inflammatory Bowel Diseases: A Systematic Review.
Kurnik-Łucka M, Pasieka P, Łączak P, Wojnarski M, Jurczyk M, Gil K
International journal of molecular sciences 2021 Nov 29;22(23)
International journal of molecular sciences 2021 Nov 29;22(23)
DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization.
Liu L, Wu Y, Wang B, Jiang Y, Lin L, Li X, Yang S
Cell death & disease 2021 May 17;12(6):500
Cell death & disease 2021 May 17;12(6):500
Increased AT(1) receptor expression mediates vasoconstriction leading to hypertension in Snx1(-/-) mice.
Liu C, Li X, Fu J, Chen K, Liao Q, Wang J, Chen C, Luo H, Jose PA, Yang Y, Yang J, Zeng C
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Aug;44(8):906-917
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Aug;44(8):906-917
Activation of dopamine receptor D1 inhibits glioblastoma tumorigenicity by regulating autophagic activity.
Yang K, Wei M, Yang Z, Fu Z, Xu R, Cheng C, Chen X, Chen S, Dammer E, Le W
Cellular oncology (Dordrecht, Netherlands) 2020 Dec;43(6):1175-1190
Cellular oncology (Dordrecht, Netherlands) 2020 Dec;43(6):1175-1190
Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation.
Wu Y, Hu Y, Wang B, Li S, Ma C, Liu X, Moynagh PN, Zhou J, Yang S
Molecular cell 2020 Apr 2;78(1):42-56.e6
Molecular cell 2020 Apr 2;78(1):42-56.e6
Development of a PC12 Cell Based Assay for Screening Catechol-O-methyltransferase Inhibitors.
Zhang G, Buchler IP, DePasquale M, Wormald M, Liao G, Wei H, Barrow JC, Carr GV
ACS chemical neuroscience 2019 Oct 16;10(10):4221-4226
ACS chemical neuroscience 2019 Oct 16;10(10):4221-4226
Validation of the targeted metabolomic pathway in the hippocampus and comparative analysis with the prefrontal cortex of social defeat model mice.
Xu K, He Y, Chen X, Tian Y, Cheng K, Zhang L, Wang Y, Yang D, Wang H, Wu Z, Li Y, Lan T, Dong Z, Xie P
Journal of neurochemistry 2019 Jun;149(6):799-810
Journal of neurochemistry 2019 Jun;149(6):799-810
Gender-dependent and genotype-sensitive monoaminergic changes induced by polychlorinated biphenyl 153 in the rat brain.
Dervola KS, Johansen EB, Walaas SI, Fonnum F
Neurotoxicology 2015 Sep;50:38-45
Neurotoxicology 2015 Sep;50:38-45
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome.
Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z, Zhou R
Cell 2015 Jan 15;160(1-2):62-73
Cell 2015 Jan 15;160(1-2):62-73
Vivo-morpholinos induced transient knockdown of physical activity related proteins.
Ferguson DP, Schmitt EE, Lightfoot JT
PloS one 2013;8(4):e61472
PloS one 2013;8(4):e61472
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The DRD5 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human DRD5. This antibody recognizes human, mouse, rat antigen. The DRD5 antibody has been validated for the following applications: ELISA, WB analysis.