Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 13593-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13593-1-AP, RRID:AB_2178105
- Product name
- RIOK3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RIOK3 antibody (Cat. #13593-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RIOK3 mediates the degradation of 40S ribosomes.
The integrated stress response regulates 18S nonfunctional rRNA decay in mammals.
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation.
Altered m(6)A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection.
miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1.
Huang Z, Diehl FF, Wang M, Li Y, Song A, Chen FX, Rosa-Mercado NA, Beckmann R, Green R, Cheng J
Molecular cell 2025 Feb 20;85(4):802-814.e12
Molecular cell 2025 Feb 20;85(4):802-814.e12
The integrated stress response regulates 18S nonfunctional rRNA decay in mammals.
Coria AR, Shah A, Shafieinouri M, Taylor SJ, Orgebin E, Guiblet W, Miller JT, Sharma IM, Wu CC
Molecular cell 2025 Feb 20;85(4):787-801.e8
Molecular cell 2025 Feb 20;85(4):787-801.e8
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.
Waltho A, Popp O, Lenz C, Pluska L, Lambert M, Dötsch V, Mertins P, Sommer T
Life science alliance 2024 Aug;7(8)
Life science alliance 2024 Aug;7(8)
RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis.
Yu M, Hu X, Yan J, Wang Y, Lu F, Chang J
Biomedicines 2021 Sep 17;9(9)
Biomedicines 2021 Sep 17;9(9)
Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation.
Shen Y, Tang K, Chen D, Hong M, Sun F, Wang S, Ke Y, Wu T, Sun R, Qian J, Du Y
Cell reports 2021 Jun 22;35(12):109272
Cell reports 2021 Jun 22;35(12):109272
Altered m(6)A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection.
Gokhale NS, McIntyre ABR, Mattocks MD, Holley CL, Lazear HM, Mason CE, Horner SM
Molecular cell 2020 Feb 6;77(3):542-555.e8
Molecular cell 2020 Feb 6;77(3):542-555.e8
miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1.
Zhang L, Flygare J, Wong P, Lim B, Lodish HF
Genes & development 2011 Jan 15;25(2):119-24
Genes & development 2011 Jan 15;25(2):119-24
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 13593-1-AP(RIOK3 antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 13593-1-AP(RIOK3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The RIOK3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RIOK3. This antibody recognizes human,mouse,rat antigen. The RIOK3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.