APR06411G

LY86 antibody from Leading Biology
dJ80N2.1, MD-1
Western blot
Recommended by provider
Immunohistochemistry
Recommended by provider

Antibody data

Product number
APR06411G
Provider
Leading Biology
Product name
MD-1 Antibody
Provider product page
Leading Biology - APR06411G
Antibody type
Polyclonal
Description
MD-1 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Provider Type Product Number
- No reagents -