Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS8139 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- RNPC3 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human RNPC3.
- Description
- U11/U12 snRNP 65K, also known as RBM40 (RNA-binding protein 40), RNPC3 (RNA-binding region-containing protein 3) or RNP, is a 517 amino acid nuclear protein that plays a role in pre-mRNA U12-dependent splicing by the minor spliceosome, ultimately leading to the removal of U12-type introns. Expressed at highest levels in kidney and pancreas, U11/U12 snRNP 65K is also weakly detected in placenta, heart, brain, lung, liver, thymus, colon, ovary, testis, prostate, spleen and small intestine. The gene encoding U11/U12 snRNP 65K maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson£ªs disease, Gaucher disease, schizophrenia and Usher syndrome.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of RNPC3 polyclonal antibody