CABT-BL8369

antibody from Creative Diagnostics

Targeting: TNFRSF10C CD263, DcR1, LIT, TRAILR3, TRID

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL8369

Provider

Creative Diagnostics

Product name

Anti-TNFRSF10C Monoclonal antibody, clone EKS4 [PE]

Antibody type

Monoclonal

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.

Reactivity

Human

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG