Antibody data
- Antibody Data
- Antigen structure
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- Product number
- 307002 - Provider product page
- Provider
- BioLegend
- Product name
- Purified anti-human CD263 (DcR1, TRAIL-R3)
- Antibody type
- Monoclonal
- Antigen
- Extracellular domain of DcR1-human IgG1 Fc fusion protein
- Description
- DcR1 is a 65 kD GPI-anchored member of the TNFR superfamily (TNFRSF10C) also known as TRAIL-R3, TRID, CD263, and LIT. Although not expressed by most tumors, DcR1 is expressed at low levels on normal tissues, acting as a TRAIL decoy receptor, thus inhibiting apoptosis. DcR1 is termed a decoy receptor, as it does not have a functional death domain to induce apoptosis following TRAIL ligation.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4 °C.
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