307002

antibody from BioLegend
Targeting: TNFRSF10C CD263, DcR1, LIT, TRAILR3, TRID
Provider product page for 307002
Flow cytometry

Antibody data

Product number
307002 - Provider product page
Provider
BioLegend
Product name
Purified anti-human CD263 (DcR1, TRAIL-R3)
Antibody type
Monoclonal
Antigen
Extracellular domain of DcR1-human IgG1 Fc fusion protein
Description
DcR1 is a 65 kD GPI-anchored member of the TNFR superfamily (TNFRSF10C) also known as TRAIL-R3, TRID, CD263, and LIT. Although not expressed by most tumors, DcR1 is expressed at low levels on normal tissues, acting as a TRAIL decoy receptor, thus inhibiting apoptosis. DcR1 is termed a decoy receptor, as it does not have a functional death domain to induce apoptosis following TRAIL ligation.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4 °C.
TNFRSF10C protein structure - 307002 shown in red.