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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [2]
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- Product number
- NBP2-27350 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal TRAILR1/TNFRSF10A Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Curcumin enhances TRAIL-induced apoptosis of breast cancer cells by regulating apoptosis-related proteins.
Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-{kappa}B signaling pathway.
Langerhans cells and dendritic cells are cytotoxic towards HPV16 E6 and E7 expressing target cells.
CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells.
Radioresponsive tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene therapy for malignant brain tumors.
4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo.
Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle.
p53 upregulates death receptor 4 expression through an intronic p53 binding site.
Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling.
Evidence that the human death receptor 4 is regulated by activator protein 1.
Inflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cells.
Park S, Cho DH, Andera L, Suh N, Kim I
Molecular and cellular biochemistry 2013 Nov;383(1-2):39-48
Molecular and cellular biochemistry 2013 Nov;383(1-2):39-48
Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-{kappa}B signaling pathway.
Jane EP, Premkumar DR, Pollack IF
Molecular cancer therapeutics 2011 Jan;10(1):198-208
Molecular cancer therapeutics 2011 Jan;10(1):198-208
Langerhans cells and dendritic cells are cytotoxic towards HPV16 E6 and E7 expressing target cells.
Le Poole IC, ElMasri WM, Denman CJ, Kroll TM, Bommiasamy H, Lyons Eiben G, Kast WM
Cancer immunology, immunotherapy : CII 2008 Jun;57(6):789-97
Cancer immunology, immunotherapy : CII 2008 Jun;57(6):789-97
CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells.
Lin YD, Chen S, Yue P, Zou W, Benbrook DM, Liu S, Le TC, Berlin KD, Khuri FR, Sun SY
Cancer research 2008 Jul 1;68(13):5335-44
Cancer research 2008 Jul 1;68(13):5335-44
Radioresponsive tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene therapy for malignant brain tumors.
Tsurushima H, Yuan X, Dillehay LE, Leong KW
Cancer gene therapy 2007 Aug;14(8):706-16
Cancer gene therapy 2007 Aug;14(8):706-16
4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo.
Kroll TM, Bommiasamy H, Boissy RE, Hernandez C, Nickoloff BJ, Mestril R, Caroline Le Poole I
The Journal of investigative dermatology 2005 Apr;124(4):798-806
The Journal of investigative dermatology 2005 Apr;124(4):798-806
Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle.
Ren YG, Wagner KW, Knee DA, Aza-Blanc P, Nasoff M, Deveraux QL
Molecular biology of the cell 2004 Nov;15(11):5064-74
Molecular biology of the cell 2004 Nov;15(11):5064-74
p53 upregulates death receptor 4 expression through an intronic p53 binding site.
Liu X, Yue P, Khuri FR, Sun SY
Cancer research 2004 Aug 1;64(15):5078-83
Cancer research 2004 Aug 1;64(15):5078-83
Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling.
Chen X, Kandasamy K, Srivastava RK
Cancer research 2003 Mar 1;63(5):1059-66
Cancer research 2003 Mar 1;63(5):1059-66
Evidence that the human death receptor 4 is regulated by activator protein 1.
Guan B, Yue P, Lotan R, Sun SY
Oncogene 2002 May 9;21(20):3121-9
Oncogene 2002 May 9;21(20):3121-9
Inflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cells.
Bretz JD, Mezosi E, Giordano TJ, Gauger PG, Thompson NW, Baker JR Jr
Cell death and differentiation 2002 Mar;9(3):274-86
Cell death and differentiation 2002 Mar;9(3):274-86
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TRAIL R1/TNFRSF10A Antibody (32A1380) - Azide Free [NBP2-27350] - Simple Western lane view shows a specific band for TRAIL R1 in 0.5 mg/ml of Daudi lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. * Non-specific interaction with the 230 kDa Simple Western standard may be seen with this antibody
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TRAIL R1/TNFRSF10A Antibody (32A1380) - Azide Free [NBP2-27350] - Analysis of NBP2-27350 in Daudi cell lysate using DR4 antibody at 2 ug/ml. Goat anti-mouse Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
