Explore
Validate
LearnNB100-56528
antibody from Novus Biologicals
Targeting: TNFRSF10A
Apo2, CD261, DR4, TRAILR-1, TRAILR1
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- NB100-56528 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-56528, RRID:AB_838154
- Product name
- Mouse Monoclonal TRAILR1/TNFRSF10A Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. In HeLa, a 57 kDa band should be observed.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Accelerated degradation of cFLIP(L) and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis.
CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5.
Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex.
DR5 receptor mediates anoikis in human colorectal carcinoma cell lines.
Comparative analysis of apoptotic pathways in rat, mouse, and hamster spermatozoa.
Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor alpha-mediated sensitization of human breast cancer cells to chemotherapy.
Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells.
Lee SR, Quan KT, Byun HS, Park I, Kang K, Piao X, Ju E, Ro H, Na M, Hur GM
Scientific reports 2019 Sep 18;9(1):13505
Scientific reports 2019 Sep 18;9(1):13505
CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
Wen Q, Wang W, Luo J, Chu S, Chen L, Xu L, Zang H, Alnemah MM, Ma J, Fan S
Oncotarget 2016 May 10;7(19):27787-801
Oncotarget 2016 May 10;7(19):27787-801
Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5.
Di X, Zhang G, Zhang Y, Takeda K, Rivera Rosado LA, Zhang B
Oncotarget 2013 Sep;4(9):1349-64
Oncotarget 2013 Sep;4(9):1349-64
Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex.
Brooks AD, Jacobsen KM, Li W, Shanker A, Sayers TJ
Molecular cancer research : MCR 2010 May;8(5):729-38
Molecular cancer research : MCR 2010 May;8(5):729-38
DR5 receptor mediates anoikis in human colorectal carcinoma cell lines.
Laguinge LM, Samara RN, Wang W, El-Deiry WS, Corner G, Augenlicht L, Mishra L, Jessup JM
Cancer research 2008 Feb 1;68(3):909-17
Cancer research 2008 Feb 1;68(3):909-17
Comparative analysis of apoptotic pathways in rat, mouse, and hamster spermatozoa.
Cisternas P, Moreno RD
Molecular reproduction and development 2006 Oct;73(10):1318-25
Molecular reproduction and development 2006 Oct;73(10):1318-25
Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor alpha-mediated sensitization of human breast cancer cells to chemotherapy.
Xu J, Zhou JY, Wu GS
Cancer research 2006 Oct 15;66(20):10092-9
Cancer research 2006 Oct 15;66(20):10092-9
Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells.
Jin F, Liu X, Zhou Z, Yue P, Lotan R, Khuri FR, Chung LW, Sun SY
Cancer research 2005 Jul 15;65(14):6354-63
Cancer research 2005 Jul 15;65(14):6354-63
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TRAIL R1/TNFRSF10A Antibody (32A242) [NB100-56528] - Analysis of 20 ug of total cell lysate from HeLa cells with DR4 antibody at 2 ug/ml. Goat anti-mouse Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
