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LearnALX-804-297TS-T100
antibody from Enzo Life Sciences
Targeting: TNFRSF10A
Apo2, CD261, DR4, TRAILR-1, TRAILR1
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations [0]
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- Product number
- ALX-804-297TS-T100 - Provider product page
- Provider
- Enzo Life Sciences
- Product name
- TRAIL-R1 (human) monoclonal antibody (HS101) (ATTO 647N conjugate)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length protein
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- HS101
- Vial size
- 100 tests
- Storage
- +4°C
- Handling
- Do not freeze. Protect from light.
Submitted references Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sezary syndrome T-cells associated with impaired death receptor and FLICE-inhibitory protein expression.
Casein kinase I attenuates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by regulating the recruitment of fas-associated death domain and procaspase-8 to the death-inducing signaling complex.
IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells.
Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.
TRAIL regulates normal erythroid maturation through an ERK-dependent pathway.
cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes.
Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation.
TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus.
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.
Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
Contassot E, Kerl K, Roques S, Shane R, Gaide O, Dupuis M, Rook AH, French LE
Blood 2008 May 1;111(9):4780-7
Blood 2008 May 1;111(9):4780-7
Casein kinase I attenuates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by regulating the recruitment of fas-associated death domain and procaspase-8 to the death-inducing signaling complex.
Izeradjene K, Douglas L, Delaney AB, Houghton JA
Cancer research 2004 Nov 1;64(21):8036-44
Cancer research 2004 Nov 1;64(21):8036-44
IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells.
Tecchio C, Huber V, Scapini P, Calzetti F, Margotto D, Todeschini G, Pilla L, Martinelli G, Pizzolo G, Rivoltini L, Cassatella MA
Blood 2004 May 15;103(10):3837-44
Blood 2004 May 15;103(10):3837-44
Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.
Ganten TM, Haas TL, Sykora J, Stahl H, Sprick MR, Fas SC, Krueger A, Weigand MA, Grosse-Wilde A, Stremmel W, Krammer PH, Walczak H
Cell death and differentiation 2004 Jul;11 Suppl 1:S86-96
Cell death and differentiation 2004 Jul;11 Suppl 1:S86-96
TRAIL regulates normal erythroid maturation through an ERK-dependent pathway.
Secchiero P, Melloni E, Heikinheimo M, Mannisto S, Di Pietro R, Iacone A, Zauli G
Blood 2004 Jan 15;103(2):517-22
Blood 2004 Jan 15;103(2):517-22
cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes.
Wachter T, Sprick M, Hausmann D, Kerstan A, McPherson K, Stassi G, Bröcker EB, Walczak H, Leverkus M
The Journal of biological chemistry 2004 Dec 17;279(51):52824-34
The Journal of biological chemistry 2004 Dec 17;279(51):52824-34
Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation.
Leverkus M, Sprick MR, Wachter T, Mengling T, Baumann B, Serfling E, Bröcker EB, Goebeler M, Neumann M, Walczak H
Molecular and cellular biology 2003 Feb;23(3):777-90
Molecular and cellular biology 2003 Feb;23(3):777-90
TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus.
Washburn B, Weigand MA, Grosse-Wilde A, Janke M, Stahl H, Rieser E, Sprick MR, Schirrmacher V, Walczak H
Journal of immunology (Baltimore, Md. : 1950) 2003 Feb 15;170(4):1814-21
Journal of immunology (Baltimore, Md. : 1950) 2003 Feb 15;170(4):1814-21
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.
Sprick MR, Rieser E, Stahl H, Grosse-Wilde A, Weigand MA, Walczak H
The EMBO journal 2002 Sep 2;21(17):4520-30
The EMBO journal 2002 Sep 2;21(17):4520-30
Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
Söderström TS, Poukkula M, Holmström TH, Heiskanen KM, Eriksson JE
Journal of immunology (Baltimore, Md. : 1950) 2002 Sep 15;169(6):2851-60
Journal of immunology (Baltimore, Md. : 1950) 2002 Sep 15;169(6):2851-60
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