SM7118P
antibody from Acris Antibodies GmbH
Targeting: TNFRSF10A
Apo2, CD261, DR4, TRAILR-1, TRAILR1
Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- SM7118P - Provider product page
- Provider
- Acris Antibodies GmbH
- Proper citation
- Acris Antibodies GmbH Cat#SM7118P, RRID:AB_980614
- Product name
- anti CD261 / TRAILR1
- Antibody type
- Monoclonal
- Antigen
- Peptide corresponding to amino acid 1 to 20 of Human DR4 mature protein
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 32A1380
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
Submitted references 4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo.
Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle.
p53 upregulates death receptor 4 expression through an intronic p53 binding site.
Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation.
Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling.
Evidence that the human death receptor 4 is regulated by activator protein 1.
Inflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cells.
Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, lymphotoxin-alpha(1)beta(2), Fas ligand, and TNF-related apoptosis-inducing ligand.
Differential expression of members of the tumor necrosis factor alpha-related apoptosis-inducing ligand pathway in prostate cancer cells.
Glioma cells deficient in urokinase plaminogen activator receptor expression are susceptible to tumor necrosis factor-alpha-related apoptosis-inducing ligand-induced apoptosis.
Kroll TM, Bommiasamy H, Boissy RE, Hernandez C, Nickoloff BJ, Mestril R, Caroline Le Poole I
The Journal of investigative dermatology 2005 Apr;124(4):798-806
The Journal of investigative dermatology 2005 Apr;124(4):798-806
Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle.
Ren YG, Wagner KW, Knee DA, Aza-Blanc P, Nasoff M, Deveraux QL
Molecular biology of the cell 2004 Nov;15(11):5064-74
Molecular biology of the cell 2004 Nov;15(11):5064-74
p53 upregulates death receptor 4 expression through an intronic p53 binding site.
Liu X, Yue P, Khuri FR, Sun SY
Cancer research 2004 Aug 1;64(15):5078-83
Cancer research 2004 Aug 1;64(15):5078-83
Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation.
Shigeno M, Nakao K, Ichikawa T, Suzuki K, Kawakami A, Abiru S, Miyazoe S, Nakagawa Y, Ishikawa H, Hamasaki K, Nakata K, Ishii N, Eguchi K
Oncogene 2003 Mar 20;22(11):1653-62
Oncogene 2003 Mar 20;22(11):1653-62
Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling.
Chen X, Kandasamy K, Srivastava RK
Cancer research 2003 Mar 1;63(5):1059-66
Cancer research 2003 Mar 1;63(5):1059-66
Evidence that the human death receptor 4 is regulated by activator protein 1.
Guan B, Yue P, Lotan R, Sun SY
Oncogene 2002 May 9;21(20):3121-9
Oncogene 2002 May 9;21(20):3121-9
Inflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cells.
Bretz JD, Mezosi E, Giordano TJ, Gauger PG, Thompson NW, Baker JR Jr
Cell death and differentiation 2002 Mar;9(3):274-86
Cell death and differentiation 2002 Mar;9(3):274-86
Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, lymphotoxin-alpha(1)beta(2), Fas ligand, and TNF-related apoptosis-inducing ligand.
Lu G, Janjic BM, Janjic J, Whiteside TL, Storkus WJ, Vujanovic NL
Journal of immunology (Baltimore, Md. : 1950) 2002 Feb 15;168(4):1831-9
Journal of immunology (Baltimore, Md. : 1950) 2002 Feb 15;168(4):1831-9
Differential expression of members of the tumor necrosis factor alpha-related apoptosis-inducing ligand pathway in prostate cancer cells.
Sridhar S, Ali AA, Liang Y, El Etreby MF, Lewis RW, Kumar MV
Cancer research 2001 Oct 1;61(19):7179-83
Cancer research 2001 Oct 1;61(19):7179-83
Glioma cells deficient in urokinase plaminogen activator receptor expression are susceptible to tumor necrosis factor-alpha-related apoptosis-inducing ligand-induced apoptosis.
Krishnamoorthy B, Darnay B, Aggarwal B, Dinh DH, Kouraklis G, Olivero WC, Gujrati M, Rao JS
Clinical cancer research : an official journal of the American Association for Cancer Research 2001 Dec;7(12):4195-201
Clinical cancer research : an official journal of the American Association for Cancer Research 2001 Dec;7(12):4195-201
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Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Western blot analysis of 15 µg of total cell lysate from Daudi cells with anti-DR4 SM7118P at 2 µg/ml.