Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- GTX28414 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX28414, RRID:AB_367920
- Product name
- DR4 antibody
- Antibody type
- Polyclonal
- Reactivity
- Human
- Host
- Rabbit
Submitted references The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl.
Luteolin sensitizes human 786-O renal cell carcinoma cells to TRAIL-induced apoptosis.
WEE1 inhibition sensitizes basal breast cancer cells to TRAIL-induced apoptosis.
Dine JL, O'Sullivan CC, Voeller D, Greer YE, Chavez KJ, Conway CM, Sinclair S, Stone B, Amiri-Kordestani L, Merchant AS, Hewitt SM, Steinberg SM, Swain SM, Lipkowitz S
Breast cancer research and treatment 2016 Jan;155(2):235-51
Breast cancer research and treatment 2016 Jan;155(2):235-51
Luteolin sensitizes human 786-O renal cell carcinoma cells to TRAIL-induced apoptosis.
Ou YC, Li JR, Kuan YH, Raung SL, Wang CC, Hung YY, Pan PH, Lu HC, Chen CJ
Life sciences 2014 Apr 1;100(2):110-7
Life sciences 2014 Apr 1;100(2):110-7
WEE1 inhibition sensitizes basal breast cancer cells to TRAIL-induced apoptosis.
Garimella SV, Rocca A, Lipkowitz S
Molecular cancer research : MCR 2012 Jan;10(1):75-85
Molecular cancer research : MCR 2012 Jan;10(1):75-85
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Western blot analysis of DR4 in HeLa cell lysate with DR4 antibody (GTX28414) at 1μg/ml.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunocytochemical staining of DR4 in Jurkat cells with DR4 antibody (GTX28414) at 10μg/ml.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemistry of DR4 in human spleen tissue with DR4 antibody at 5 μg/mL.