ABIN1002205
antibody from antibodies-online
Targeting: TNFRSF10A
Apo2, CD261, DR4, TRAILR-1, TRAILR1
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1002205 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Rabbit polyclol DR4 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human DR4 protein.
- Description
- Antibody is purified via DEAE-column chromatography.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.
Submitted references TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB.
The receptor for the cytotoxic ligand TRAIL.
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family.
Identification and characterization of a new member of the TNF family that induces apoptosis.
Schneider P, Thome M, Burns K, Bodmer JL, Hofmann K, Kataoka T, Holler N, Tschopp J
Immunity 1997 Dec;7(6):831-6
Immunity 1997 Dec;7(6):831-6
The receptor for the cytotoxic ligand TRAIL.
Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM
Science (New York, N.Y.) 1997 Apr 4;276(5309):111-3
Science (New York, N.Y.) 1997 Apr 4;276(5309):111-3
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family.
Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A
The Journal of biological chemistry 1996 May 31;271(22):12687-90
The Journal of biological chemistry 1996 May 31;271(22):12687-90
Identification and characterization of a new member of the TNF family that induces apoptosis.
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, Sutherland GR, Smith TD, Rauch C, Smith CA
Immunity 1995 Dec;3(6):673-82
Immunity 1995 Dec;3(6):673-82
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