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- References [20]
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- Immunohistochemistry [1]
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- Product number
- 11590-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11590-1-AP, RRID:AB_10644290
- Product name
- RGS5 antibody
- Antibody type
- Polyclonal
- Description
- RGS5 antibody (Cat. #11590-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Transfer of Damaged Mitochondria from Cancer Cells to Cancer-Associated Fibroblasts Promotes Tyrosine Kinase Inhibitor Tolerance in EGFR-Mutant Lung Cancer.
Single-cell transcriptome profiling reveals herpesviral manipulation of host processes in spleen of gibel carp infected with a Cyvirus cyprinidallo2.
Single-cell transcriptomics reveal the effects of chemoimmunotherapy on hypopharyngeal cancer and its tumor microenvironment.
Umbilical Cord-Mesenchymal Stromal Cell-Derived Extracellular Vesicles Target the Liver to Improve Neurovascular Health in Type 2 Diabetes With Non-Alcoholic Fatty Liver Disease.
Overexpression of MEOX2 inhibits breast cancer cell metastasis by targeting oxidative stress-induced RGS5.
The mechanism of RGS5 regulating gastric cancer mismatch repair protein.
Cancer-Associated Fibroblast-Induced Remodeling of Tumor Microenvironment in Recurrent Bladder Cancer.
RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment.
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma.
Resmetirom Ameliorates NASH-Model Mice by Suppressing STAT3 and NF-κB Signaling Pathways in an RGS5-Dependent Manner.
Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma.
Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia.
Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis.
A regulator of G protein signaling 5 marked subpopulation of vascular smooth muscle cells is lost during vascular disease.
RGS5: a novel role as a hypoxia-responsive protein that suppresses chemokinetic and chemotactic migration in brain pericytes.
An integrated map of fibroblastic populations in human colon mucosa and cancer tissues.
Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma.
HuR (Human Antigen R) Regulates the Contraction of Vascular Smooth Muscle and Maintains Blood Pressure.
Beta-Arrestin1 Prevents Preeclampsia by Downregulation of Mechanosensitive AT1-B2 Receptor Heteromers.
Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds.
Liu T, Huang S, Li Z, Li J, Sun Q, Wang Q, Shen Z, Xia Z, Meng F, Xu Y, Xia W, Tan J, Yin R
Cancer research 2026 Mar 2;86(5):1215-1231
Cancer research 2026 Mar 2;86(5):1215-1231
Single-cell transcriptome profiling reveals herpesviral manipulation of host processes in spleen of gibel carp infected with a Cyvirus cyprinidallo2.
Ke F, Zhou Y, Chen BQ, Wang HY, Zhao Z, Zhang QY
PLoS pathogens 2026 Apr;22(4):e1014114
PLoS pathogens 2026 Apr;22(4):e1014114
Single-cell transcriptomics reveal the effects of chemoimmunotherapy on hypopharyngeal cancer and its tumor microenvironment.
Zhu X, Xu H, Zhao Y, Diao W, Yan F, Zhu Y, Zhao T, Chen X
Oral oncology 2025 Jun;165:107347
Oral oncology 2025 Jun;165:107347
Umbilical Cord-Mesenchymal Stromal Cell-Derived Extracellular Vesicles Target the Liver to Improve Neurovascular Health in Type 2 Diabetes With Non-Alcoholic Fatty Liver Disease.
Du M, Yang H, Niu J, Huang J, Wang L, Xi J, Meng P, Liu Z, Ma G, Li J, Liu X, Guo L, Hu M, Tian Z, Liu B, Liu W, Shetty AK, Wu S, Baskys A, Long Q
Journal of extracellular vesicles 2025 Jul;14(7):e70125
Journal of extracellular vesicles 2025 Jul;14(7):e70125
Overexpression of MEOX2 inhibits breast cancer cell metastasis by targeting oxidative stress-induced RGS5.
Tang Y, Luo J, Jiang B, Deng J, Li J, Qin L
In vitro cellular & developmental biology. Animal 2025 Aug;61(7):871-885
In vitro cellular & developmental biology. Animal 2025 Aug;61(7):871-885
The mechanism of RGS5 regulating gastric cancer mismatch repair protein.
Yang Z, Zhang R, Liu J, Tian S, Zhang H, Zeng L, Zhang Y, Gao L, Wang M, Shan W, Liu J
Molecular carcinogenesis 2024 Sep;63(9):1750-1767
Molecular carcinogenesis 2024 Sep;63(9):1750-1767
Cancer-Associated Fibroblast-Induced Remodeling of Tumor Microenvironment in Recurrent Bladder Cancer.
Liang T, Tao T, Wu K, Liu L, Xu W, Zhou D, Fang H, Ding Q, Huang G, Wu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(31):e2303230
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(31):e2303230
RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment.
Kong P, Wang X, Gao YK, Zhang DD, Huang XF, Song Y, Zhang WD, Guo RJ, Li H, Han M
Biology direct 2023 Nov 20;18(1):78
Biology direct 2023 Nov 20;18(1):78
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma.
Jia Y, Zhang B, Zhang C, Kwong DL, Chang Z, Li S, Wang Z, Han H, Li J, Zhong Y, Sui X, Fu L, Guan X, Qin Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Mar;10(7):e2204565
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Mar;10(7):e2204565
Resmetirom Ameliorates NASH-Model Mice by Suppressing STAT3 and NF-κB Signaling Pathways in an RGS5-Dependent Manner.
Wang X, Wang L, Geng L, Tanaka N, Ye B
International journal of molecular sciences 2023 Mar 19;24(6)
International journal of molecular sciences 2023 Mar 19;24(6)
Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma.
Hao B, Zhang Z, Lu Z, Xiong J, Fan T, Song C, He R, Zhang L, Pan S, Li D, Meng H, Lin W, Luo B, Yang J, Li N, Geng Q
Translational oncology 2023 Jan;27:101568
Translational oncology 2023 Jan;27:101568
Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia.
Xu X, Zhang DD, Kong P, Gao YK, Huang XF, Song Y, Zhang WD, Guo RJ, Li CL, Chen BW, Sun Y, Zhao YB, Jia FY, Wang X, Zhang F, Han M
Cell reports 2023 Aug 29;42(8):112869
Cell reports 2023 Aug 29;42(8):112869
Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis.
Zhang S, Fang W, Zhou S, Zhu D, Chen R, Gao X, Li Z, Fu Y, Zhang Y, Yang F, Zhao J, Wu H, Wang P, Shen Y, Shen S, Xu G, Wang L, Yan C, Zou X, Chen D, Lv Y
Nature communications 2023 Aug 23;14(1):5123
Nature communications 2023 Aug 23;14(1):5123
A regulator of G protein signaling 5 marked subpopulation of vascular smooth muscle cells is lost during vascular disease.
Gao YK, Guo RJ, Xu X, Huang XF, Song Y, Zhang DD, Chen N, Wang XW, Liang CX, Kong P, Han M
PloS one 2022;17(3):e0265132
PloS one 2022;17(3):e0265132
RGS5: a novel role as a hypoxia-responsive protein that suppresses chemokinetic and chemotactic migration in brain pericytes.
Enström A, Carlsson R, Özen I, Paul G
Biology open 2022 Oct 15;11(10)
Biology open 2022 Oct 15;11(10)
An integrated map of fibroblastic populations in human colon mucosa and cancer tissues.
Li S, Lu R, Shu L, Chen Y, Zhao J, Dai J, Huang Q, Li X, Meng W, Long F, Li Y, Fan C, Zhou Z, Mo X
Communications biology 2022 Dec 3;5(1):1326
Communications biology 2022 Dec 3;5(1):1326
Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma.
Chen Z, Zhou L, Liu L, Hou Y, Xiong M, Yang Y, Hu J, Chen K
Nature communications 2020 Oct 8;11(1):5077
Nature communications 2020 Oct 8;11(1):5077
HuR (Human Antigen R) Regulates the Contraction of Vascular Smooth Muscle and Maintains Blood Pressure.
Liu S, Jiang X, Lu H, Xing M, Qiao Y, Zhang C, Zhang W
Arteriosclerosis, thrombosis, and vascular biology 2020 Apr;40(4):943-957
Arteriosclerosis, thrombosis, and vascular biology 2020 Apr;40(4):943-957
Beta-Arrestin1 Prevents Preeclampsia by Downregulation of Mechanosensitive AT1-B2 Receptor Heteromers.
Quitterer U, Fu X, Pohl A, Bayoumy KM, Langer A, AbdAlla S
Cell 2019 Jan 10;176(1-2):318-333.e19
Cell 2019 Jan 10;176(1-2):318-333.e19
Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds.
Guerrero-Juarez CF, Dedhia PH, Jin S, Ruiz-Vega R, Ma D, Liu Y, Yamaga K, Shestova O, Gay DL, Yang Z, Kessenbrock K, Nie Q, Pear WS, Cotsarelis G, Plikus MV
Nature communications 2019 Feb 8;10(1):650
Nature communications 2019 Feb 8;10(1):650
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 11590-1-AP(RGS5 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RGS5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RGS5. This antibody recognizes human, mouse, rat antigen. The RGS5 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
