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- Antibody Data
- Antigen structure
- References [12]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12189-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12189-1-AP, RRID:AB_2254520
- Product name
- SFRP2 antibody
- Antibody type
- Polyclonal
- Description
- SFRP2 antibody (Cat. #12189-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exosomal miRNA-218-5p derived from low-passage dermal papilla cells modulates hair follicle growth and development.
Sfrp2-deficient colonic fibroblasts drive mucosal inflammation and epithelial injury in ulcerative colitis.
KSRP-mediated Wnt/β-catenin activation promotes follicular thyroid cancer progression and stemness.
Secreted frizzled-related protein 2 monoclonal antibody-mediated IFN-ϒ reprograms tumor-associated macrophages to suppress triple negative breast cancer.
SFRP1 and SFRP2 jointly regulate normal and malignant hematopoietic progenitors by influencing mesenchymal cells in the hematopoietic niche.
The role of dexamethasone in mediating the contradictory effects of Wnt antagonists SFRP2 and SFRP3 on human hair follicle growth.
m6A Methyltransferase METTL3 Reduces Hippocampal Neuron Apoptosis in a Mouse Model of Autism Through the MALAT1/SFRP2/Wnt/β-catenin Axis.
Fucoidan Inhibits the Progression of Hepatocellular Carcinoma via Causing lncRNA LINC00261 Overexpression.
MicroRNA-500a promotes migration and invasion in hepatocellular carcinoma by activating the Wnt/β-catenin signaling pathway.
Tenotomy immobilization as a model to investigate skeletal muscle fibrosis (with emphasis on Secreted frizzled-related protein 2).
Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs.
Digital gene expression tag profiling analysis of the gene expression patterns regulating the early stage of mouse spermatogenesis.
Zhao B, Cai J, Wang M, Li J, Yao S, Bao Z, Chen Y, Wu X
Non-coding RNA research 2026 Jun;18:1-11
Non-coding RNA research 2026 Jun;18:1-11
Sfrp2-deficient colonic fibroblasts drive mucosal inflammation and epithelial injury in ulcerative colitis.
Zhu M, Diao Z, Hu L, Fan Z
Cellular immunology 2025 Sep-Oct;415-416:105003
Cellular immunology 2025 Sep-Oct;415-416:105003
KSRP-mediated Wnt/β-catenin activation promotes follicular thyroid cancer progression and stemness.
Pan KF, Chou HL, Wang WL, Chen BR, Hsiao M, Hua KT, Wu MH
British journal of cancer 2025 Nov;133(8):1111-1121
British journal of cancer 2025 Nov;133(8):1111-1121
Secreted frizzled-related protein 2 monoclonal antibody-mediated IFN-ϒ reprograms tumor-associated macrophages to suppress triple negative breast cancer.
Hsu L, Siegel J, Nasarre P, Oberholtzer N, Mukherjee R, Hilliard E, Chakraborty P, Burge RA, O'Quinn EC, Sweatt O, Kassir MF, Hobbs GA, Ostrowski M, Broome AM, Mehrotra S, Klauber-DeMore N
Breast cancer research : BCR 2025 Dec 5;27(1):209
Breast cancer research : BCR 2025 Dec 5;27(1):209
SFRP1 and SFRP2 jointly regulate normal and malignant hematopoietic progenitors by influencing mesenchymal cells in the hematopoietic niche.
Tsutsumi H, Kumagai F, Tsutsui K, Maekawa A, Ohno A, Okamoto H, Ueno A, Kuga A, Hasegawa N, Ito M
Biochemical and biophysical research communications 2025 Aug 8;774:152081
Biochemical and biophysical research communications 2025 Aug 8;774:152081
The role of dexamethasone in mediating the contradictory effects of Wnt antagonists SFRP2 and SFRP3 on human hair follicle growth.
Hamida OB, Kim MK, Kwack MH
Scientific reports 2023 Oct 2;13(1):16504
Scientific reports 2023 Oct 2;13(1):16504
m6A Methyltransferase METTL3 Reduces Hippocampal Neuron Apoptosis in a Mouse Model of Autism Through the MALAT1/SFRP2/Wnt/β-catenin Axis.
Ming Y, Deng Z, Tian X, Jia Y, Ning M, Cheng S
Psychiatry investigation 2022 Oct;19(10):771-787
Psychiatry investigation 2022 Oct;19(10):771-787
Fucoidan Inhibits the Progression of Hepatocellular Carcinoma via Causing lncRNA LINC00261 Overexpression.
Ma D, Wei J, Chen S, Wang H, Ning L, Luo SH, Liu CL, Song G, Yao Q
Frontiers in oncology 2021;11:653902
Frontiers in oncology 2021;11:653902
MicroRNA-500a promotes migration and invasion in hepatocellular carcinoma by activating the Wnt/β-catenin signaling pathway.
Guo Y, Chen L, Sun C, Yu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:13-20
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:13-20
Tenotomy immobilization as a model to investigate skeletal muscle fibrosis (with emphasis on Secreted frizzled-related protein 2).
Akpulat U, Onbaşılar İ, Kocaefe YÇ
Physiological genomics 2016 Jun;48(6):397-408
Physiological genomics 2016 Jun;48(6):397-408
Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs.
Zhou C, Yang X, Sun Y, Yu H, Zhang Y, Jin Y
Cell research 2016 Feb;26(2):171-89
Cell research 2016 Feb;26(2):171-89
Digital gene expression tag profiling analysis of the gene expression patterns regulating the early stage of mouse spermatogenesis.
Zhang X, Hao L, Meng L, Liu M, Zhao L, Hu F, Ding C, Wang Y, He B, Pan Y, Fang W, Chen J, Hu S, Jia M
PloS one 2013;8(3):e58680
PloS one 2013;8(3):e58680
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Y79 cells were subjected to SDS PAGE followed by western blot with 12189-1-AP(SFRP2 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SFRP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SFRP2. This antibody recognizes human,mouse,rat antigen. The SFRP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
