Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS9251 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Nkx 2.8 (P37) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 11-60 of Human Nkx-2.8.
- Description
- Members of the NK-2 family of homeodomain proteins, which include Nkx-2.2, Nkx-2.5, Nkx-2.6 and Nkx-2.8, are key regulators of growth and development in several tissues, including brain, heart and pancreas. Nkx-2.2 is responsible for directing ventral neuronal patterning in response to graded Shh signaling. Nkx-2.5, also designated cardiac specific homeobox protein (Csx), is a homolog of the Drosophila tinman protein and is essential for normal cardiovascular development. Nkx-2.6, also a homolog of the Drosophila tinman protein, is expressed in the caudal pharyngeal pouches, the caudal heart progenitors, the sinus venosus, the outflow tract of the heart and in a short segment of the gut between stages E8.5 and E10.5 of embryogenesis. Nkx-2.8, also designated NK-2 homolog H, NKX2H or Nkx-2.9, is a nuclear protein that contains one homeobox DNA-binding domain, indicating a possible role in development.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of Nkx-2.8 (P37) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264.7 whole cell lysateLane3:Hela whole cell lysate