orb2643293

antibody from Biorbyt
Targeting: NKX2-8 Nkx2-9, NKX2.8, NKX2H
Provider product page for orb2643293
Western blot
ELISA
Flow cytometry

Antibody data

Product number
orb2643293 - Provider product page
Provider
Biorbyt
Product name
NKX2.8 Antibody
Antibody type
Monoclonal
Description
The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
NKX28/2548
Vial size
100 ug
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
NKX2-8 protein structure - orb2643293 shown in red.