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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [9]
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- Product number
- ABIN117951 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cullin 5 (CUL5) (N-Term), (AA 4-18) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to amino acids 4-18 of Human Cul5 (N-terminus) coupled coupled to KLH.
- Description
- Delipidation and defibrination.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Antigen sequence
Human Cullin 5 (780 aa 90.9 kDa): 1
matsnllknk gslqfedkwd fmrpivlkll r
qesvtkqqw fdlfsdvhav clwddkgpak 61
ihqalkedil efikqaqarv lshqddtall ka
yivewrkf ftqcdilpkp fcqleitlmg 121
kqgsnkksnv edsivrklml dtwnesifsn ik
nrlqdsam klvhaerlge afdsqlvigv 181
resyvnlcsn pedklqiyrd nfekayldst er
fyrtqaps ylqqngvqny mkyadaklke 241
eekralryle trrecnsvea lmeccvnalv ts
fketilae cqgmikrnet eklhlmfslm 301
dkvpngiepm lkdleehiis agladmvaaa et
ittdseky veqlltlfnr fsklvkeafq 361
ddprfltard kaykavvnda tifklelplk qk
gvglktqp eskcpellan ycdmllrktp 421
lskkltseei eaklkevllv lkyvqnkdvf mr
yhkahltr rlildisads eieenmvewl 481
revgmpadyv nklarmfqdi kvsedlnqaf ke
mhknnkla lpadsvniki lnagawsrss 541
ekvfvslpte ledlipevee fykknhsgrk lh
whhlmsng iitfknevgq ydlevttfql 601
avlfawnqrp rekisfenlk latelpdael rr
tlwslvaf pklkrqvlly epqvnspkdf 661
tegtlfsvnq efsliknakv qkrgkinlig rl
qlttermr eeenegivql rilrtqeaii 721
qimkmrkkis naqlqtelve ilknmflpqk km
ikeqiewl iehkyirrde sdintfiyma- Epitope
- N-Term,AA 4-18
- Vial size
- 0.1 mL
- Concentration
- 85.0 mg/mL (by Refractometry)
- Storage
- Store undiluted at 2-8°C for up to one month or in aliquots at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Biliary complications associated with selective internal radiation (SIR) therapy for unresectable liver malignancies.
Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex.
NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases.
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex.
Ubiquitin and its kin: how close are the family ties?
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A.
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.
Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins.
Ng SS, Yu SC, Lai PB, Lau WY
Digestive diseases and sciences 2008 Oct;53(10):2813-7
Digestive diseases and sciences 2008 Oct;53(10):2813-7
Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex.
Yu X, Yu Y, Liu B, Luo K, Kong W, Mao P, Yu XF
Science (New York, N.Y.) 2003 Nov 7;302(5647):1056-60
Science (New York, N.Y.) 2003 Nov 7;302(5647):1056-60
NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases.
Liu J, Furukawa M, Matsumoto T, Xiong Y
Molecular cell 2002 Dec;10(6):1511-8
Molecular cell 2002 Dec;10(6):1511-8
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex.
Querido E, Blanchette P, Yan Q, Kamura T, Morrison M, Boivin D, Kaelin WG, Conaway RC, Conaway JW, Branton PE
Genes & development 2001 Dec 1;15(23):3104-17
Genes & development 2001 Dec 1;15(23):3104-17
Ubiquitin and its kin: how close are the family ties?
Jentsch S, Pyrowolakis G
Trends in cell biology 2000 Aug;10(8):335-42
Trends in cell biology 2000 Aug;10(8):335-42
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Ohta T, Michel JJ, Schottelius AJ, Xiong Y
Molecular cell 1999 Apr;3(4):535-41
Molecular cell 1999 Apr;3(4):535-41
Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A.
Michel JJ, Xiong Y
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998 Jun;9(6):435-49
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998 Jun;9(6):435-49
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.
Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM
Cell 1996 Jun 14;85(6):829-39
Cell 1996 Jun 14;85(6):829-39
Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins.
Mathias N, Johnson SL, Winey M, Adams AE, Goetsch L, Pringle JR, Byers B, Goebl MG
Molecular and cellular biology 1996 Dec;16(12):6634-43
Molecular and cellular biology 1996 Dec;16(12):6634-43
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