MA5-28132

antibody from Invitrogen Antibodies
Targeting: CHRNB1 CHRNB
Provider product page for MA5-28132
Western blot
Immunoprecipitation
Immunohistochemistry
Flow cytometry

Antibody data

Product number
MA5-28132 - Provider product page
Provider
Invitrogen Antibodies
Product name
CHRNB1 Monoclonal Antibody (B3)
Antibody type
Monoclonal
Antigen
Other
Description
Description: The IT2.2 monoclonal antibody reacts with human CD86, an ~80 kDa surface receptor also known as B7-2. CD86 and CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed at low levels on B cells, macrophages, and dendritic cells and is upregulated on B cells through a variety of surface stimuli including the BCR complex, CD40 and some cytokine receptors. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). The interaction of CD86 with its ligands plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation supports its major contribution during the primary phase of an immune response.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
B3
Vial size
100 µg
Concentration
1 mg/mL
Storage
4°C or -20°C if preferred
CHRNB1 protein structure - MA5-28132 shown in red.