Antibody data
- Antibody Data
- Antigen structure
- References [177]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 12802-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12802-1-AP, RRID:AB_2102442
- Product name
- FABP4 antibody
- Antibody type
- Polyclonal
- Description
- FABP4 antibody (Cat. #12802-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references PDGFRα-positive mesenchymal stem/stromal cells contribute to autonomous vascular formation through in-body tissue architecture.
Isoliquiritigenin restores bone homeostasis in osteoporotic rats by enhancing BMSCs osteogenesis via ERK1/2-mTOR-HIF-1α-glycolytic axis and suppressing inflammation.
Gentiana szechenyii Kanitz Compounds Regulate Lipopolysaccharide-Induced Inflammation and Mitochondrial Autophagy Via the Toll-Like Receptor 4-Nuclear Factor Kappa B Pathway.
CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels.
FABP4 expression in neutrophils as a predictor of sepsis and SI-ARDS based on BALF transcriptome and peripheral blood validation.
Adipogenic transdifferentiation reprograms EMT-high PDAC cells into a post-mitotic adipocyte-like state and limits metastasis.
Polystyrene nanoplastics promote adipogenesis by stimulating nuclear translocation of PPARγ.
Deficiency of Med1 in keratinocytes augments dermal fibrosis and inflammation in scleroderma.
The role of FOXO1/PPARγ in atrazine-induced hepatic lipid metabolism disorders.
Isomeranzin activates Gnas-AMPK signaling to drive white adipose browning and curb obesity in mice.
SIRT1-mediated FABP4 destabilization attenuates fibrosis and ferroptosis in non-alcoholic fatty liver disease.
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
FABP4 is highly expressed in preeclamptic placentas and regulates trophoblast lipid metabolism, mitochondrial function, and oxidative stress in vitro.
Dingxin recipe Ⅲ ameliorates atherosclerosis through stard4-mediated regulation of hepatic lipid metabolism.
PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation.
NAT10-mediated N4-acetylcytidine modification in KLF9 mRNA promotes adipogenesis.
Effects of Mn Deficiency on Hepatic Oxidative Stress, Lipid Metabolism, Inflammatory Response, and Transcriptomic Profile in Mice.
Analysis and verification of potential ferroptosis-related diagnostic markers in the early stage of metabolic dysfunction-associated steatohepatitis.
m(6)A-methylated TAL1 exacerbates lipid accumulation in ethylene bisdithiocarbamate metabolite-induced anorectal malformations in rat fetuses via miR-205/LCOR signaling.
TRIM34 inhibits triple-negative breast cancer progression by attenuating fatty acid synthesis via facilitating FASN ubiquitination.
Activation of STING pathway by mitochondrial fission negatively regulates adipogenic differentiation of 3 T3-L1 cells.
Off-target engagement of sotorasib with PPARγ via FABP4: a novel mechanism driving interstitial lung disease.
H3K18 lactylation-hexokinase 2 positive feedback loop promotes osteogenesis of ASPCs in facial infiltrating lipomatosis.
Bispecific aptamers target thyrotropin receptor (TSHR) and insulin growth factor-1 receptor (IGF-1R) for the improvement of orbital fibroblasts activation in the treatment of thyroid-associated ophthalmopathy.
Rhein suppresses osteosarcoma progression via modulating the miR-328-3p/TCF7L2/FABP4 axis.
Hyperactivation of the m(6)A demethylase FTO to down-regulate SLC7A11/xCT-mediated redox homeostasis and epigenetic remodeling in facial infiltrating lipomatosis.
Bushen Huatan formula alleviates polycystic ovary syndrome in rats by activating the PI3K/Akt pathway to inhibit GSDMD-mediated pyroptosis and mitochondrial damage.
Establishment of spontaneously immortalized Japanese eel muscle-derived preadipocyte cell lines for cultured seafood production.
Sodium hexametaphosphate mitigates calcium oxalate stone formation by modulating crystallization and maintaining PPARα signaling.
Human umbilical cord mesenchymal stem cells improve bone marrow hematopoiesis through regulation of bone marrow adipose tissue.
Blockade of ITGA2/3/5 Promotes Adipogenic Differentiation of Human Adipose-derived Mesenchymal Stem Cells.
Cryoshocked Adipocytes Mediated Dual-Modal Strategy Combining Photodynamic Therapy and Triptolide Palmitate for Pulmonary Metastatic Melanoma Treatment.
FABP4 Mediates Inflammation to Regulate Endometrial Epithelial Cell Function During Early Gestation in Sheep.
Butyrate Ameliorates Graves' Orbitopathy Through Regulating Orbital Fibroblast Phenotypes and Gut Microbiota.
Inhibiting fatty acid-binding protein 4 reverses inflammation and apoptosis in wasp sting-induced acute kidney injury.
Rbm39 ameliorates metabolic dysfunction-associated steatotic liver disease by regulating Apob and Fabp4.
Integrated transcriptomics and metabolomics unravel the key metabolic pathways involved in the therapeutic mechanism of Salvianic acid A against hepatic fibrosis.
An Injectable Antioxidant Parathyroid Hormone Related Supramolecular Peptide Nanofiber Hydrogel for Repairing Osteoporotic Bone Defects.
FABP4 Inhibitor Improves Right Ventricular Fibrosis in Metabolic Syndrome- Related Pulmonary Hypertension due to Left Heart Disease in Mice.
Ursolic acid suppresses triple-negative breast cancer progression through mediating FABP4/PPARG pathway.
ALKBH5 regulates intrauterine adhesion progression through m6A dependent FABP4 mRNA stabilization and serum lipid metabolism.
Epac1 Inhibits Orbital Fibroblast Activation to Ameliorate Thyroid-Associated Orbitopathy-Like Features Through the JAK/STAT Signaling Pathway.
A novel human specific lncRNA MEK6-AS1 regulates adipogenesis and fatty acid biosynthesis by stabilizing MEK6 mRNA.
Effects of resveratrol on growth performance, meat quality, and intramuscular fat deposition in finishing steers.
Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation.
DHA Improves neurodevelopmental abnormalities in offspring of gestational diabetes mellitus patients via the PPAR-γ/FATP4 pathway.
Isoliquiritigenin Ameliorates High-Fat Diet-Induced Obesity in Mice by Activating Brown Adipose Tissue.
Arthrocolin B Impairs Adipogenesis via Delaying Cell Cycle Progression During the Mitotic Clonal Expansion Period.
Inhibition of the calcineurin/forkhead box O1/fatty acid binding protein 4 pathway prevents SERCA2 dysfunction-induced foam cell formation and atherosclerosis.
Syncytin-1 deficiency impairs placental nutrient transport via PI3K/Akt/mTOR signaling.
Angiopoietin-like 8 governs osteoblast-adipocyte lineage commitment during skeletal aging.
PSPC1-SMAD3 axis regulates iron-induced beiging of adipocytes in white adipose tissue.
Residual tumor cells after insufficient radiofrequency ablation promote lung metastasis by educating CD177(hi)PAD4(hi) neutrophils.
Targeting OxLDL-mediated CD36 + CAF reprogramming potentiates PD-1 immunotherapy in osteosarcoma.
Unravelling the Role of PIEZO1 in Adipogenesis of Fibrogenic/Adipogenic Progenitors for Muscle Fat Infiltration After Rotator Cuff Tear.
Multi-omics reveals miR-181a-5p regulates PPAR-driven lipid metabolism in Oral squamous cell carcinoma: Insights from CRISPR/Cas9 knockout models.
Proteomic analysis reveals that Acalypha australis L. mitigates chronic colitis by modulating the FABP4/PPARγ/NF-κB signaling pathway.
NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin-mediated FAK/AKT signaling.
Chemically Modified PPARγ mRNA Unleashes Adipogenic Potential in 3T3-L1-Predipocytes: An Approach for Accelerated Wound Healing.
Exercise attenuates high-fat diet-induced PVAT dysfunction through improved inflammatory response and BMP4-regulated adipose tissue browning.
FABP4, GINS2 and CBX7 Expression in Cancer Cervix Tissues: Clinical, Pathological and Prognostic Implications.
High Fatty Acid-Binding Protein 4 Expression Associated with Favorable Clinical Characteristics and Prognosis in Papillary Thyroid Carcinoma.
Sortilin-mediated translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in male mice.
FABP4 deficiency ameliorates alcoholic steatohepatitis in mice via inhibition of p53 signaling pathway.
Dahuang Huanglian Xiexin Decoction ameliorates obesity via modulating adipocyte differentiation and lipid degradation through inhibiting endoplasmic reticulum stress.
Gut microbiota-derived acetic acids promoted sepsis-induced acute respiratory distress syndrome by delaying neutrophil apoptosis through FABP4.
Exosomal miR-1a-3p derived from glucocorticoid-stimulated M1 macrophages promotes the adipogenic differentiation of BMSCs in glucocorticoid-associated osteonecrosis of the femoral head by targeting Cebpz.
Preliminary study of the role of histone deacetylase (HDAC) in steroid-induced avascular necrosis of the femoral head induced by BMSC adipogenic differentiation.
circARID1A Inhibits Tail Fat Cell Differentiation in Guangling Large-Tailed Sheep by Regulating the miR-493-3p/YTHDF2 Axis.
l-arginine promotes angio-osteogenesis to enhance oxidative stress-inhibited bone formation by ameliorating mitophagy.
Effect of LncRNA LOC106505926 on myogenesis and Lipogenesis of porcine primary cells.
Alleviative effects of the parthenolide derivative ACT001 on insulin resistance induced by sodium propionate combined with a high-fat diet and its potential mechanisms.
Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy.
Shift work promotes adipogenesis via cortisol-dependent downregulation of EGR3-HDAC6 pathway.
EEF1B2 regulates bone marrow-derived mesenchymal stem cells bone-fat balance via Wnt/β-catenin signaling.
Upregulation of FABP4 induced inflammation in the pathogenesis of chronic tendinopathy.
Chrysanthemum morifolium attenuates metabolic and alcohol-associated liver disease via gut microbiota and PPARα/γ activation.
Time-restricted feeding ameliorates non-alcoholic fatty liver disease through modulating hepatic nicotinamide metabolism via gut microbiota remodeling.
MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning.
LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism.
Single-cell transcriptome analysis of the mouse lungs during the injury and recovery periods after lipopolysaccharide administration.
Diet-induced obesity and aging-induced upregulation of Trib3 interfere with energy homeostasis by downregulating the thermogenic capacity of BAT.
Ginsenoside Rb1 affects mitochondrial Ca(2+) transport and inhibits fat deposition and fibrosis by regulating the wnt signaling pathway to treat rotator cuff tears via docking with SFRP1.
circNDUFA13 stimulates adipogenesis of bone marrow-derived mesenchymal stem cells via interaction with STAT3.
Elucidating the Role of circTIAM1 in Guangling Large-Tailed Sheep Adipocyte Proliferation and Differentiation via the miR-485-3p/PLCB1 Pathway.
GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell Activation.
Bidirectional effect of vitamin D on brown adipogenesis of C3H10T1/2 fibroblast-like cells.
Differences in histomorphology and expression of key lipid regulated genes of four adipose tissues from Tibetan pigs.
Aquaporin-7 Facilitates Proliferation and Adipogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Regulating Hydrogen Peroxide Transport.
Phosphorylated YBX2 is stabilized to promote glycolysis in brown adipocytes.
Methylation of lncSHGL promotes adipocyte differentiation by regulating miR-149/Mospd3 axis.
TET2 is recruited by CREB to promote Cebpb, Cebpa, and Pparg transcription by facilitating hydroxymethylation during adipocyte differentiation.
Targeting FABP4 in elderly mice rejuvenates liver metabolism and ameliorates aging-associated metabolic disorders.
Apolipoprotein E facilitates titanium implant osseointegration by regulating osteogenesis-lipogenesis balance.
Reduction of NADPH oxidase 4 in adipocytes contributes to the anti-obesity effect of dihydroartemisinin.
Bone marrow mesenchymal stem cell-derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway.
Adipocytes promote pancreatic cancer migration and invasion through fatty acid metabolic reprogramming.
Intra-tumoral infiltration of adipocyte facilitates the activation of antitumor immune response in pancreatic ductal adenocarcinoma.
Caveolae-associated protein 3 promotes adipogenic differentiation of porcine preadipocytes by promoting extracellular signal-regulated kinase phosphorylation.
circINSR Inhibits Adipogenic Differentiation of Adipose-Derived Stromal Vascular Fractions through the miR-152/MEOX2 Axis in Sheep.
Oridonin attenuates atherosclerosis by inhibiting foam macrophage formation and inflammation through FABP4/PPARγ signalling.
LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs.
A cell-autonomous mechanism regulates BCAA catabolism in white adipocytes and systemic metabolic balance.
Inhibition of Fatty Acid β-Oxidation by Fatty Acid Binding Protein 4 Induces Ferroptosis in HK2 Cells Under High Glucose Conditions.
Tax1 binding protein 3 regulates osteogenic and adipogenic differentiation through inactivating Wnt/β-catenin signalling.
Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity.
Upregulated estrogen receptors impairs myogenesis and elevates adipogenesis related factor levels in the paravertebral muscles of patients with idiopathic scoliosis.
Tumor Microenvironment Heterogeneity-Based Score System Predicts Clinical Prognosis and Response to Immune Checkpoint Blockade in Multiple Colorectal Cancer Cohorts.
Proteomic profiling reveals the potential mechanisms and regulatory targets of sirtuin 4 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's mouse model.
Knockdown of CDC20 promotes adipogenesis of bone marrow-derived stem cells by modulating β-catenin.
Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension.
Vasorin contributes to lung injury via FABP4-mediated inflammation.
Dysregulated adipose tissue expansion and impaired adipogenesis in Prader-Willi syndrome children before obesity-onset.
DEPTOR exacerbates bone-fat imbalance in osteoporosis by transcriptionally modulating BMSC differentiation.
Long noncoding RNA ZFAS1 suppresses osteogenic differentiation of bone marrow-derived mesenchymal stem cells by upregulating miR-499-EPHA5 axis.
N-myc downstream regulated gene 1 suppresses osteoblast differentiation through inactivating Wnt/β-catenin signaling.
miR-669a-5p promotes adipogenic differentiation and induces browning in preadipocytes.
Contribution of Oxidative Stress Induced by Sonodynamic Therapy to the Calcium Homeostasis Imbalance Enhances Macrophage Infiltration in Glioma Cells.
Fatty acid-binding protein 4 is a therapeutic target for septic acute kidney injury by regulating inflammatory response and cell apoptosis.
Quantitative proteomic analysis identified differentially expressed proteins with tail/rump fat deposition in Chinese thin- and fat-tailed lambs.
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells.
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters.
High-mobility group AT-Hook 1 mediates the role of nuclear factor I/X in osteogenic differentiation through activating canonical Wnt signaling.
Single-cell RNA sequencing analysis to characterize cells and gene expression landscapes in atrial septal defect.
FABP4 is an independent risk factor for lymph node metastasis and poor prognosis in patients with cervical cancer.
Expression of fatty acid-binding protein-4 in gastrointestinal stromal tumors and its significance for prognosis.
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
SNHG16/miR-485-5p/BMP7 axis modulates osteogenic differentiation of human bone marrow-derived mesenchymal stem cells.
Effect of Notch pathway on lipid accumulation induced by mono-2-ethylhexyl phthalate on 3T3-L1 cells.
Maternal high-fat-diet exposure is associated with elevated blood pressure and sustained increased leptin levels through epigenetic memory in offspring.
Effects of the FABP4 gene on steroid hormone secretion in goose ovarian granulosa cells.
Histone Deacetylase Inhibitor SAHA Induces Expression of Fatty Acid-Binding Protein 4 and Inhibits Replication of Human Cytomegalovirus.
IL-20 is involved in obesity by modulation of adipogenesis and macrophage dysregulation.
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
FTO inhibits UPR(mt)-induced apoptosis by activating JAK2/STAT3 pathway and reducing m6A level in adipocytes.
Expression and enhancement of FABP4 in septoclasts of the growth plate in FABP5-deficient mouse tibiae.
Insulin receptor substrate-1 inhibits high-fat diet-induced obesity by browning of white adipose tissue through miR-503.
Lysophosphatidic acid receptor 4 regulates osteogenic and adipogenic differentiation of progenitor cells via inactivation of RhoA/ROCK1/β-catenin signaling.
Histone demethylase KDM4A regulates adipogenic and osteogenic differentiation via epigenetic regulation of C/EBPα and canonical Wnt signaling.
miR-196b-5p controls adipocyte differentiation and lipogenesis through regulating mTORC1 and TGF-β signaling.
m(6)A mRNA methylation controls autophagy and adipogenesis by targeting Atg5 and Atg7.
Effects of di (2-ethylhexyl) phthalate and high-fat diet on lipid metabolism in rats by JAK2/STAT5.
PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission.
Breed difference and regulatory role of CRTC3 in porcine intramuscular adipocyte.
miR-27a is an important adipogenesis regulator associated with differential lipid accumulation between intramuscular and subcutaneous adipose tissues of sheep.
IL-29 promoted obesity-induced inflammation and insulin resistance.
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Cerasus humilis Cherry Polyphenol Reduces High-Fat Diet-Induced Obesity in C57BL/6 Mice by Mitigating Fat Deposition, Inflammation, and Oxidation.
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
Significant Role of Dicer and miR-223 in Adipose Tissue of Polycystic Ovary Syndrome Patients.
A Novel Regulatory Circuit "C/EBPα/miR-20a-5p/TOB2" Regulates Adipogenesis and Lipogenesis.
A novel long noncoding RNA PGC1β-OT1 regulates adipocyte and osteoblast differentiation through antagonizing miR-148a-3p.
Aspirin inhibits adipogenesis of tendon stem cells and lipids accumulation in rat injury tendon through regulating PTEN/PI3K/AKT signalling.
Glucocorticoid Enhanced the Expression of Ski in Osteonecrosis of Femoral Head: The Effect on Adipogenesis of Rabbit BMSCs.
Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.
Cancer‑associated adipocytes exhibit distinct phenotypes and facilitate tumor progression in pancreatic cancer.
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.
Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling.
The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.
Comparative proteomic analysis of ovaries from Huoyan geese between pre-laying and laying periods using an iTRAQ-based approach.
IL-1α inhibits proliferation and adipogenic differentiation of human adipose-derived mesenchymal stem cells through NF-κB- and ERK1/2-mediated proinflammatory cytokines.
Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics for the investigation of the effect of Hugan Qingzhi on non-alcoholic fatty liver disease in rats.
Pygo2 Regulates Adiposity and Glucose Homeostasis via β-Catenin-Axin2-GSK3β Signaling Pathway.
miR-128-3p regulates 3T3-L1 adipogenesis and lipolysis by targeting Pparg and Sertad2.
miR-148a-3p regulates adipocyte and osteoblast differentiation by targeting lysine-specific demethylase 6b.
Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins.
Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity.
Iron overload inhibits osteogenic commitment and differentiation of mesenchymal stem cells via the induction of ferritin.
Quantitative proteomic analysis reveals that anti-cancer effects of selenium-binding protein 1 in vivo are associated with metabolic pathways.
miR-223 Regulates Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells Through a C/EBPs/miR-223/FGFR2 Regulatory Feedback Loop.
Nuclear envelope proteins Nesprin2 and LaminA regulate proliferation and apoptosis of vascular endothelial cells in response to shear stress.
miR-204-5p promotes the adipogenic differentiation of human adipose-derived mesenchymal stem cells by modulating DVL3 expression and suppressing Wnt/β-catenin signaling.
miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis.
miR-140-5p regulates adipocyte differentiation by targeting transforming growth factor-β signaling.
miR-30e reciprocally regulates the differentiation of adipocytes and osteoblasts by directly targeting low-density lipoprotein receptor-related protein 6.
Rosiglitazone disrupts endosteal bone formation during distraction osteogenesis by local adipocytic infiltration.
Morikawa S, Yoda M, Ouchi T, Yasui T, Fukuda K, Sugimoto M, Harada R, Matsumoto T, Mabuchi Y, Tsuji O, Nagoshi N, Kase Y, Okano H, Kitagawa Y, Nakamura M, Nakagawa T, Nakayama Y
PloS one 2026;21(4):e0347197
PloS one 2026;21(4):e0347197
Isoliquiritigenin restores bone homeostasis in osteoporotic rats by enhancing BMSCs osteogenesis via ERK1/2-mTOR-HIF-1α-glycolytic axis and suppressing inflammation.
Chang H, Li Y, Wang Z, Fang Z, Chen H, Xu C, Jiao X, Gan Y
International immunopharmacology 2026 May 1;176:116440
International immunopharmacology 2026 May 1;176:116440
Gentiana szechenyii Kanitz Compounds Regulate Lipopolysaccharide-Induced Inflammation and Mitochondrial Autophagy Via the Toll-Like Receptor 4-Nuclear Factor Kappa B Pathway.
Zhang H, Zhang Z, Hu J, Li Y, Nan X, Yang F
Chemistry & biodiversity 2026 Mar;23(3):e03838
Chemistry & biodiversity 2026 Mar;23(3):e03838
CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels.
Lu Q, Zheng Q, Zhou Z, Chen Y, Chen Y, Chen W, Wang J, Guo R, Wu R, Chen L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e22295
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e22295
FABP4 expression in neutrophils as a predictor of sepsis and SI-ARDS based on BALF transcriptome and peripheral blood validation.
Xuan W, Liang C, Yang S, Zheng L, Wu X, Zhang X
Chinese medical journal 2026 Mar 5;139(5):754-766
Chinese medical journal 2026 Mar 5;139(5):754-766
Adipogenic transdifferentiation reprograms EMT-high PDAC cells into a post-mitotic adipocyte-like state and limits metastasis.
Qian Y, Yan Z, Wang J, An Q, Luo J, Mutailifu M, Tulamaiti A, Zhang XL, Zhang ZG, Li DX
Cell death & disease 2026 Mar 20;17(1)
Cell death & disease 2026 Mar 20;17(1)
Polystyrene nanoplastics promote adipogenesis by stimulating nuclear translocation of PPARγ.
Zheng Y, Liu Z, Zhao Z, Sheng C, Li W, Tang D, Ning Y, Zhou R, Li A, Zhou Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116030
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116030
Deficiency of Med1 in keratinocytes augments dermal fibrosis and inflammation in scleroderma.
Luo J, Kang Y, Zhang Z, Zhang E, Huang J, Zhu Q, Guo Q, Song S, Wang B, Li M, Yuan Q, Li H, Zhao D, Chen H, Wang S, Li Y, Zhang B, He J, Hu L
International immunopharmacology 2026 Jul 15;181:116667
International immunopharmacology 2026 Jul 15;181:116667
The role of FOXO1/PPARγ in atrazine-induced hepatic lipid metabolism disorders.
Yingchao H, Haoyan M, Zengchen W, Haotang Z, Tong L, Ying Q, Xiaotong W, Yuezhu Z
Toxicology letters 2026 Jan;415:111797
Toxicology letters 2026 Jan;415:111797
Isomeranzin activates Gnas-AMPK signaling to drive white adipose browning and curb obesity in mice.
Shi M, Ye Y, Hu L, Yan Y, Jiang S, Wang P, Li F, Ai M, Huang J, Yang L, Huang K, Liang M
EMBO molecular medicine 2026 Jan;18(1):55-90
EMBO molecular medicine 2026 Jan;18(1):55-90
SIRT1-mediated FABP4 destabilization attenuates fibrosis and ferroptosis in non-alcoholic fatty liver disease.
Qiu H, Chen K, Qiu Y, Yang Y, Wang T, Wang W, Jiang L
Clinical and experimental medicine 2026 Feb 6;26(1):129
Clinical and experimental medicine 2026 Feb 6;26(1):129
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Shen Y, Zhang M, Yang T, Wu Y, Qiu Y, Zhang L, Li F, Chen M, Chen Q, Wei W, Li H, Shen Y
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Cellular & molecular biology letters 2026 Feb 11;31(1):22
FABP4 is highly expressed in preeclamptic placentas and regulates trophoblast lipid metabolism, mitochondrial function, and oxidative stress in vitro.
Sun H, Wang Q, Wu L, Jing R, Xuan S, Zhuang W
BMC pregnancy and childbirth 2026 Feb 10;26(1)
BMC pregnancy and childbirth 2026 Feb 10;26(1)
Dingxin recipe Ⅲ ameliorates atherosclerosis through stard4-mediated regulation of hepatic lipid metabolism.
Gu Y, Jin Y, Zhao H, Tang J, Li Z, Cheng S, Zhang Y, He P, Han Z, He J, Zhou F, Liu X, Jia Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157924
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157924
PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation.
Chen H, Huang Z, Chang R, Gao W, Qiu Y, Sun B, Hua C, Lin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e23139
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e23139
NAT10-mediated N4-acetylcytidine modification in KLF9 mRNA promotes adipogenesis.
Wan X, Wang L, Khan MA, Peng L, Sun X, Yi X, Wang Z, Chen K
Cell death and differentiation 2025 Sep;32(9):1613-1629
Cell death and differentiation 2025 Sep;32(9):1613-1629
Effects of Mn Deficiency on Hepatic Oxidative Stress, Lipid Metabolism, Inflammatory Response, and Transcriptomic Profile in Mice.
Hu Y, Tang S, Wang S, Sun C, Chen B, Cai B, Yin H
Nutrients 2025 Sep 23;17(19)
Nutrients 2025 Sep 23;17(19)
Analysis and verification of potential ferroptosis-related diagnostic markers in the early stage of metabolic dysfunction-associated steatohepatitis.
Li Q, Zhang Q, Ren A, Zhang H, Liu L
Biochemical and biophysical research communications 2025 Sep 12;779:152406
Biochemical and biophysical research communications 2025 Sep 12;779:152406
m(6)A-methylated TAL1 exacerbates lipid accumulation in ethylene bisdithiocarbamate metabolite-induced anorectal malformations in rat fetuses via miR-205/LCOR signaling.
Yao Y, Yang S, Bai Y, Yuan Z, Yang Z
Ecotoxicology and environmental safety 2025 Sep 1;302:118594
Ecotoxicology and environmental safety 2025 Sep 1;302:118594
TRIM34 inhibits triple-negative breast cancer progression by attenuating fatty acid synthesis via facilitating FASN ubiquitination.
Li Y, Shan J, Liu S, Shen Y, Niu L, Mao Q, Chen X
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167958
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167958
Activation of STING pathway by mitochondrial fission negatively regulates adipogenic differentiation of 3 T3-L1 cells.
Ma K, Sun H, Wu X, Quan J, Tang R, Liu W, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T
Cellular signalling 2025 Oct;134:111948
Cellular signalling 2025 Oct;134:111948
Off-target engagement of sotorasib with PPARγ via FABP4: a novel mechanism driving interstitial lung disease.
Zhang J, Li J, Cheng M, Zhou H, Zhang X, Yan H, Xu Z, Yang B, He Q, Gao Z, Chen X, Luo P
Cell communication and signaling : CCS 2025 Oct 2;23(1):416
Cell communication and signaling : CCS 2025 Oct 2;23(1):416
H3K18 lactylation-hexokinase 2 positive feedback loop promotes osteogenesis of ASPCs in facial infiltrating lipomatosis.
Chen H, Hua C, Chang SJ, Qiu Y, Lin X, Sun B
Stem cell research & therapy 2025 Oct 1;16(1):538
Stem cell research & therapy 2025 Oct 1;16(1):538
Bispecific aptamers target thyrotropin receptor (TSHR) and insulin growth factor-1 receptor (IGF-1R) for the improvement of orbital fibroblasts activation in the treatment of thyroid-associated ophthalmopathy.
Xie B, Zhang F, Yin J, Ouyang S, Cao J, Tan Y, Xiong W
International journal of biological macromolecules 2025 Nov;330(Pt 1):147867
International journal of biological macromolecules 2025 Nov;330(Pt 1):147867
Rhein suppresses osteosarcoma progression via modulating the miR-328-3p/TCF7L2/FABP4 axis.
Zhao X, Wang R, Xia X, Han C, Wei W, Zhao W, Ji R, Zhang L
Biochemical pharmacology 2025 Nov;241:117152
Biochemical pharmacology 2025 Nov;241:117152
Hyperactivation of the m(6)A demethylase FTO to down-regulate SLC7A11/xCT-mediated redox homeostasis and epigenetic remodeling in facial infiltrating lipomatosis.
Chen H, Gao W, Huang Z, Chang SJ, Qiu Y, Sun B, Lin X, Hua C
Free radical biology & medicine 2025 Nov;239:432-448
Free radical biology & medicine 2025 Nov;239:432-448
Bushen Huatan formula alleviates polycystic ovary syndrome in rats by activating the PI3K/Akt pathway to inhibit GSDMD-mediated pyroptosis and mitochondrial damage.
Xiong Q, Yang J, Liu Q, Yu P, Shen M, Liang J
Journal of ovarian research 2025 Nov 24;18(1):309
Journal of ovarian research 2025 Nov 24;18(1):309
Establishment of spontaneously immortalized Japanese eel muscle-derived preadipocyte cell lines for cultured seafood production.
Kishino E, Saegusa S, Ikeda D
NPJ science of food 2025 Nov 20;9(1):240
NPJ science of food 2025 Nov 20;9(1):240
Sodium hexametaphosphate mitigates calcium oxalate stone formation by modulating crystallization and maintaining PPARα signaling.
Xian JY, Peng L, Long J, Chen XW, Huang LH, Sun XY
Urolithiasis 2025 Nov 18;53(1):222
Urolithiasis 2025 Nov 18;53(1):222
Human umbilical cord mesenchymal stem cells improve bone marrow hematopoiesis through regulation of bone marrow adipose tissue.
Feng J, Zhang M, Ren H, Ren Y, Hao Z, Bian S, Cui J, Li S, Xu J, Daniel MM, Ren F, Xu Z, Tan Y, Chen X, Zhang Y, Chang J, Wang H
Molecular and cellular biochemistry 2025 May;480(5):3033-3049
Molecular and cellular biochemistry 2025 May;480(5):3033-3049
Blockade of ITGA2/3/5 Promotes Adipogenic Differentiation of Human Adipose-derived Mesenchymal Stem Cells.
Li Y, Wang W, Liu Z, Liu G, Li X
Cell biochemistry and biophysics 2025 Mar;83(1):1105-1111
Cell biochemistry and biophysics 2025 Mar;83(1):1105-1111
Cryoshocked Adipocytes Mediated Dual-Modal Strategy Combining Photodynamic Therapy and Triptolide Palmitate for Pulmonary Metastatic Melanoma Treatment.
Li A, Qi F, Zeng Y, Liu R, Cai H, He M, Li D, Gu Y, Liu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(9):e2414307
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(9):e2414307
FABP4 Mediates Inflammation to Regulate Endometrial Epithelial Cell Function During Early Gestation in Sheep.
Chen Y, Liu C, Liu Z, Yu H, Peng X, Wang J, Hu G
Veterinary medicine and science 2025 Mar;11(2):e70193
Veterinary medicine and science 2025 Mar;11(2):e70193
Butyrate Ameliorates Graves' Orbitopathy Through Regulating Orbital Fibroblast Phenotypes and Gut Microbiota.
Ouyang P, Qi J, Tong B, Li Y, Cao J, Wang L, Niu T, Qi X
Investigative ophthalmology & visual science 2025 Mar 3;66(3):5
Investigative ophthalmology & visual science 2025 Mar 3;66(3):5
Inhibiting fatty acid-binding protein 4 reverses inflammation and apoptosis in wasp sting-induced acute kidney injury.
Li L, Yuan H, Li H, Cheng R, Zhou Z, Hu F, Xu L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Jun;200:115428
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Jun;200:115428
Rbm39 ameliorates metabolic dysfunction-associated steatotic liver disease by regulating Apob and Fabp4.
Zhuang C, Cui F, Chen J, He D, Sun T, Wang P
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167815
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167815
Integrated transcriptomics and metabolomics unravel the key metabolic pathways involved in the therapeutic mechanism of Salvianic acid A against hepatic fibrosis.
Zhang Y, Zhang Y, Zhang J, Lai W, He G, Shi J, Zhang C, Xiong L, Wang T, Ye F, Jiang X
Toxicology and applied pharmacology 2025 Jul;500:117398
Toxicology and applied pharmacology 2025 Jul;500:117398
An Injectable Antioxidant Parathyroid Hormone Related Supramolecular Peptide Nanofiber Hydrogel for Repairing Osteoporotic Bone Defects.
Feng Q, Li H, Wang Y, Wang J, Zhang Z, Hao Z, Chen R, Chen T, Shi G, Chen J, Zhu T, Du J, Hu Y, Li J
ACS applied materials & interfaces 2025 Jul 9;17(27):38890-38911
ACS applied materials & interfaces 2025 Jul 9;17(27):38890-38911
FABP4 Inhibitor Improves Right Ventricular Fibrosis in Metabolic Syndrome- Related Pulmonary Hypertension due to Left Heart Disease in Mice.
Qiu H, Chen W, Chen J, Jun L, Chen Y, Tan Y, Wang T, Li J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70833
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70833
Ursolic acid suppresses triple-negative breast cancer progression through mediating FABP4/PPARG pathway.
Deng Y, Wu J, Pan D, Su W, Wang S
European journal of medical research 2025 Jul 2;30(1):550
European journal of medical research 2025 Jul 2;30(1):550
ALKBH5 regulates intrauterine adhesion progression through m6A dependent FABP4 mRNA stabilization and serum lipid metabolism.
Yang X, Feng Q
Communications biology 2025 Jul 1;8(1):973
Communications biology 2025 Jul 1;8(1):973
Epac1 Inhibits Orbital Fibroblast Activation to Ameliorate Thyroid-Associated Orbitopathy-Like Features Through the JAK/STAT Signaling Pathway.
Liu R, Xin X, Ma S, Guo J, Wu C, Qi X, Luo B
Investigative ophthalmology & visual science 2025 Jul 1;66(9):68
Investigative ophthalmology & visual science 2025 Jul 1;66(9):68
A novel human specific lncRNA MEK6-AS1 regulates adipogenesis and fatty acid biosynthesis by stabilizing MEK6 mRNA.
Li D, Chen Y, Zhu X, Yang Y, Li H, Zhao RC
Journal of biomedical science 2025 Jan 8;32(1):6
Journal of biomedical science 2025 Jan 8;32(1):6
Effects of resveratrol on growth performance, meat quality, and intramuscular fat deposition in finishing steers.
Yang M, Ji K, Liu X, Wang Z, Lin X, Zhao H, Zhang X
Journal of animal science 2025 Jan 4;103
Journal of animal science 2025 Jan 4;103
Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation.
Zhou C, Zhong R, Zhang L, Yang R, Luo Y, Lei H, Li L, Cao J, Yuan Z, Tan X, Xie M, Qu H, He Z
Discover oncology 2025 Jan 15;16(1):47
Discover oncology 2025 Jan 15;16(1):47
DHA Improves neurodevelopmental abnormalities in offspring of gestational diabetes mellitus patients via the PPAR-γ/FATP4 pathway.
Jiang Y, Zhou X, He Z, Wei L, Zhu S, Zhang H, Zhang J, Chen Y, Du Y, Ding W, Wang S, Wang Z, Feng L
Biochemical pharmacology 2025 Feb;232:116726
Biochemical pharmacology 2025 Feb;232:116726
Isoliquiritigenin Ameliorates High-Fat Diet-Induced Obesity in Mice by Activating Brown Adipose Tissue.
Zhao L, Li M, Zhu Q, Fang X, Yang H, Zhao Y
International journal of molecular sciences 2025 Feb 14;26(4)
International journal of molecular sciences 2025 Feb 14;26(4)
Arthrocolin B Impairs Adipogenesis via Delaying Cell Cycle Progression During the Mitotic Clonal Expansion Period.
Cao G, Liao X, Zhao S, Li M, Xie Z, Yang J, Li Y, Zhu Z, Jin X, Huang R, Guo Z, Niu X, Ji X
International journal of molecular sciences 2025 Feb 10;26(4)
International journal of molecular sciences 2025 Feb 10;26(4)
Inhibition of the calcineurin/forkhead box O1/fatty acid binding protein 4 pathway prevents SERCA2 dysfunction-induced foam cell formation and atherosclerosis.
Zhu B, Luo S, Su H, Zhang W, Chen Q, Zhang Y, Liu C, Li P, Wang T, Tong X, Hu P
British journal of pharmacology 2025 Dec;182(24):5953-5968
British journal of pharmacology 2025 Dec;182(24):5953-5968
Syncytin-1 deficiency impairs placental nutrient transport via PI3K/Akt/mTOR signaling.
Chen XL, Gong XX, Xiong ZL, Zhou D, Yang J, Zhang HF, Xue YS, Wang YN, Chen HB
The Journal of nutritional biochemistry 2025 Dec;146:110060
The Journal of nutritional biochemistry 2025 Dec;146:110060
Angiopoietin-like 8 governs osteoblast-adipocyte lineage commitment during skeletal aging.
Guo Y, Zhang Z, He J, Luo P, Wang Z, Zhu Y, Meng X, Pan L, Kan R, Xiang Y, Mao B, He Y, Wang S, Yang Y, Guo F, You H, Li F, Li D, Chen Y, Yu X
JCI insight 2025 Dec 8;10(23)
JCI insight 2025 Dec 8;10(23)
PSPC1-SMAD3 axis regulates iron-induced beiging of adipocytes in white adipose tissue.
Peng XM, He R, Wang HY, Liu JD, Xie YY, Wang ZH, Deng HY, Wang WS, Zhu ZZ, Ge J, Liu YL, Gao RH, Yang M, Li DP, Kang QQ, Pan RP, Chen Y
Cell communication and signaling : CCS 2025 Dec 4;24(1):12
Cell communication and signaling : CCS 2025 Dec 4;24(1):12
Residual tumor cells after insufficient radiofrequency ablation promote lung metastasis by educating CD177(hi)PAD4(hi) neutrophils.
Huang N, Fang Y, Zheng S, Wu J, Huang G, Deng X, Guan Y, Liang B, Zeng D, Xu B, Huang Y, Rong X, Wang C, Bin J, Liao Y, Wu Z, Shi M, Liao W
Nature communications 2025 Dec 2;17(1):208
Nature communications 2025 Dec 2;17(1):208
Targeting OxLDL-mediated CD36 + CAF reprogramming potentiates PD-1 immunotherapy in osteosarcoma.
Zeng A, Chen H, Luo T, Chen W, Song Y, Xu Y, Chen Z, Tang Q, Zhu X, Deng C, Xu H, Wang A, Wu H, Song G, Lu J, Wang J
Molecular cancer 2025 Dec 18;25(1):14
Molecular cancer 2025 Dec 18;25(1):14
Unravelling the Role of PIEZO1 in Adipogenesis of Fibrogenic/Adipogenic Progenitors for Muscle Fat Infiltration After Rotator Cuff Tear.
Lin X, Song Q, Kuati A, Li Z, Zhou H, Feng S, Wang M, Zhu S, Cui G, Wang J, Shao X
Journal of cachexia, sarcopenia and muscle 2025 Aug;16(4):e70004
Journal of cachexia, sarcopenia and muscle 2025 Aug;16(4):e70004
Multi-omics reveals miR-181a-5p regulates PPAR-driven lipid metabolism in Oral squamous cell carcinoma: Insights from CRISPR/Cas9 knockout models.
Wang T, Liu Y, Wu X, Wang X, Shi S, Song X, Ma Y, Zhang Z, Gao J, Sun R, Song G
Journal of proteomics 2025 Aug 15;319:105480
Journal of proteomics 2025 Aug 15;319:105480
Proteomic analysis reveals that Acalypha australis L. mitigates chronic colitis by modulating the FABP4/PPARγ/NF-κB signaling pathway.
Quan X, Miao Z, Han R, Deng R, Cao Y, Tian J, Lu Y, Wang G, Yu X, Wu Y, Dai C
Journal of ethnopharmacology 2025 Apr 9;345:119585
Journal of ethnopharmacology 2025 Apr 9;345:119585
NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin-mediated FAK/AKT signaling.
Yuan H, Wang X, Du S, Li M, Zhu E, Zhou J, Dong Y, Wang S, Shan L, Liu Q, Wang B
Bone research 2025 Apr 11;13(1):46
Bone research 2025 Apr 11;13(1):46
Chemically Modified PPARγ mRNA Unleashes Adipogenic Potential in 3T3-L1-Predipocytes: An Approach for Accelerated Wound Healing.
Luo Z, Lu Y, Zheng S, Liu K, Fu W, Pan Y
International journal of medical sciences 2024;21(13):2480-2493
International journal of medical sciences 2024;21(13):2480-2493
Exercise attenuates high-fat diet-induced PVAT dysfunction through improved inflammatory response and BMP4-regulated adipose tissue browning.
Liu X, Jiang X, Hu J, Ding M, Lee SK, Korivi M, Qian Y, Li T, Wang L, Li W
Frontiers in nutrition 2024;11:1393343
Frontiers in nutrition 2024;11:1393343
FABP4, GINS2 and CBX7 Expression in Cancer Cervix Tissues: Clinical, Pathological and Prognostic Implications.
Elfeky MA, Faraj Saad RH, Alabiad MA, Alorini M, Hemeda R, Ali RM, Gertallah LM, Negm M, Abdou AM, Alshaikh ABA, Elmaasrawy A
Iranian journal of pathology 2024 Winter;19(1):10-21
Iranian journal of pathology 2024 Winter;19(1):10-21
High Fatty Acid-Binding Protein 4 Expression Associated with Favorable Clinical Characteristics and Prognosis in Papillary Thyroid Carcinoma.
Cheng CW, Fang WF, Yang YM, Lin JD
Endocrine pathology 2024 Sep;35(3):245-255
Endocrine pathology 2024 Sep;35(3):245-255
Sortilin-mediated translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in male mice.
Yang M, Ge J, Liu YL, Wang HY, Wang ZH, Li DP, He R, Xie YY, Deng HY, Peng XM, Wang WS, Liu JD, Zhu ZZ, Yu XF, Maretich P, Kajimura S, Pan RP, Chen Y
Nature communications 2024 Sep 5;15(1):7746
Nature communications 2024 Sep 5;15(1):7746
FABP4 deficiency ameliorates alcoholic steatohepatitis in mice via inhibition of p53 signaling pathway.
Xing H, Wu Z, Jiang K, Yuan G, Guo Z, Yu S, He S, Zhong F
Scientific reports 2024 Sep 10;14(1):21135
Scientific reports 2024 Sep 10;14(1):21135
Dahuang Huanglian Xiexin Decoction ameliorates obesity via modulating adipocyte differentiation and lipid degradation through inhibiting endoplasmic reticulum stress.
Hao L, Li M, Gu H, Li J
Prostaglandins & other lipid mediators 2024 Oct;174:106874
Prostaglandins & other lipid mediators 2024 Oct;174:106874
Gut microbiota-derived acetic acids promoted sepsis-induced acute respiratory distress syndrome by delaying neutrophil apoptosis through FABP4.
Xuan W, Wu X, Zheng L, Jia H, Zhang X, Zhang X, Cao B
Cellular and molecular life sciences : CMLS 2024 Oct 25;81(1):438
Cellular and molecular life sciences : CMLS 2024 Oct 25;81(1):438
Exosomal miR-1a-3p derived from glucocorticoid-stimulated M1 macrophages promotes the adipogenic differentiation of BMSCs in glucocorticoid-associated osteonecrosis of the femoral head by targeting Cebpz.
Duan P, Yu YL, Cheng YN, Nie MH, Yang Q, Xia LH, Ji YX, Pan ZY
Journal of nanobiotechnology 2024 Oct 22;22(1):648
Journal of nanobiotechnology 2024 Oct 22;22(1):648
Preliminary study of the role of histone deacetylase (HDAC) in steroid-induced avascular necrosis of the femoral head induced by BMSC adipogenic differentiation.
Yu YL, Duan P, Zheng L, Xu JM, Pan ZY
Journal of orthopaedic surgery and research 2024 Oct 12;19(1):645
Journal of orthopaedic surgery and research 2024 Oct 12;19(1):645
circARID1A Inhibits Tail Fat Cell Differentiation in Guangling Large-Tailed Sheep by Regulating the miR-493-3p/YTHDF2 Axis.
Shen Y, Liang Y, Yuan Z, Qiao L, Liu J, Pan Y, Yang K, Liu W
International journal of molecular sciences 2024 Nov 18;25(22)
International journal of molecular sciences 2024 Nov 18;25(22)
l-arginine promotes angio-osteogenesis to enhance oxidative stress-inhibited bone formation by ameliorating mitophagy.
Shen Y, Wang H, Xie H, Zhang J, Ma Q, Wang S, Yuan P, Xue H, Hong H, Fan S, Xu W, Xie Z
Journal of orthopaedic translation 2024 May;46:53-64
Journal of orthopaedic translation 2024 May;46:53-64
Effect of LncRNA LOC106505926 on myogenesis and Lipogenesis of porcine primary cells.
Shi M, Yang S, Zhao X, Sun D, Li Y, Yang J, Li M, Cai C, Guo X, Li B, Lu C, Cao G
BMC genomics 2024 May 30;25(1):530
BMC genomics 2024 May 30;25(1):530
Alleviative effects of the parthenolide derivative ACT001 on insulin resistance induced by sodium propionate combined with a high-fat diet and its potential mechanisms.
Yu Q, Zuo X, Bai H, Zhang S, Luan J, Zhao Q, Zhao X, Feng X
European journal of pharmacology 2024 May 15;971:176529
European journal of pharmacology 2024 May 15;971:176529
Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy.
Ling M, Qian H, Guo H
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):258-265
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):258-265
Shift work promotes adipogenesis via cortisol-dependent downregulation of EGR3-HDAC6 pathway.
Wan X, Wang L, Khan MA, Peng L, Zhang K, Sun X, Yi X, Wang Z, Chen K
Cell death discovery 2024 Mar 11;10(1):129
Cell death discovery 2024 Mar 11;10(1):129
EEF1B2 regulates bone marrow-derived mesenchymal stem cells bone-fat balance via Wnt/β-catenin signaling.
Feng S, Feng Z, Wei Y, Zheng X, Deng Z, Liao Z, Jin Y, Chen R, Zhao L
Cellular and molecular life sciences : CMLS 2024 Jun 15;81(1):260
Cellular and molecular life sciences : CMLS 2024 Jun 15;81(1):260
Upregulation of FABP4 induced inflammation in the pathogenesis of chronic tendinopathy.
Ma Z, Lee AYW, Kot CH, Yung PSH, Chen SC, Lui PPY
Journal of orthopaedic translation 2024 Jul;47:105-115
Journal of orthopaedic translation 2024 Jul;47:105-115
Chrysanthemum morifolium attenuates metabolic and alcohol-associated liver disease via gut microbiota and PPARα/γ activation.
Liu D, Zhan J, Wang S, Chen L, Zhu Q, Nie R, Zhou X, Zheng W, Luo X, Wang B, Nie J, Ye X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155774
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155774
Time-restricted feeding ameliorates non-alcoholic fatty liver disease through modulating hepatic nicotinamide metabolism via gut microbiota remodeling.
Feng R, Yang W, Feng W, Huang X, Cen M, Peng G, Wu W, Wang Z, Jing Y, Long T, Liu Y, Li Z, Chang G, Huang K
Gut microbes 2024 Jan-Dec;16(1):2390164
Gut microbes 2024 Jan-Dec;16(1):2390164
MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning.
Wang Q, Su Y, Sun R, Xiong X, Guo K, Wei M, Yang G, Ru Y, Zhang Z, Li J, Zhang J, Qiao Q, Li X
Cell & bioscience 2024 Jan 20;14(1):12
Cell & bioscience 2024 Jan 20;14(1):12
LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism.
Cai F, Liu L, Bo Y, Yan W, Tao X, Peng Y, Zhang Z, Liao Q, Yi Y
BMC cancer 2024 Feb 2;24(1):166
BMC cancer 2024 Feb 2;24(1):166
Single-cell transcriptome analysis of the mouse lungs during the injury and recovery periods after lipopolysaccharide administration.
Wang HP, He J, He JR, Li DD, Huang H, Chen B
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Dec;73(12):2087-2107
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Dec;73(12):2087-2107
Diet-induced obesity and aging-induced upregulation of Trib3 interfere with energy homeostasis by downregulating the thermogenic capacity of BAT.
Yeo H, Lim JH, Eom J, Kim M, Kwon H, Kang SW, Song Y
Experimental & molecular medicine 2024 Dec;56(12):2690-2702
Experimental & molecular medicine 2024 Dec;56(12):2690-2702
Ginsenoside Rb1 affects mitochondrial Ca(2+) transport and inhibits fat deposition and fibrosis by regulating the wnt signaling pathway to treat rotator cuff tears via docking with SFRP1.
Yin Y, Hu H, Yang Y, Wu S
Molecular medicine (Cambridge, Mass.) 2024 Dec 2;30(1):240
Molecular medicine (Cambridge, Mass.) 2024 Dec 2;30(1):240
circNDUFA13 stimulates adipogenesis of bone marrow-derived mesenchymal stem cells via interaction with STAT3.
Huang L, He S, Wang T, Long K, Ma B, Wu P, Gong Y, Zhong D, Yang Q, Wu J, Li X
Scientific reports 2024 Aug 26;14(1):19787
Scientific reports 2024 Aug 26;14(1):19787
Elucidating the Role of circTIAM1 in Guangling Large-Tailed Sheep Adipocyte Proliferation and Differentiation via the miR-485-3p/PLCB1 Pathway.
Liang Y, Zhao B, Shen Y, Peng M, Qiao L, Liu J, Pan Y, Yang K, Liu W
International journal of molecular sciences 2024 Apr 23;25(9)
International journal of molecular sciences 2024 Apr 23;25(9)
GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell Activation.
Zhang H, Zhou P, Xing W, Chen L, Zhou Y, Yang H, Fu K, Liu Z
Cellular and molecular gastroenterology and hepatology 2023;15(2):355-372
Cellular and molecular gastroenterology and hepatology 2023;15(2):355-372
Bidirectional effect of vitamin D on brown adipogenesis of C3H10T1/2 fibroblast-like cells.
Mukai T, Kusudo T
PeerJ 2023;11:e14785
PeerJ 2023;11:e14785
Differences in histomorphology and expression of key lipid regulated genes of four adipose tissues from Tibetan pigs.
Lin C, Dong Z, Song J, Wang S, Yang Y, Li H, Feng Z, Pei Y
PeerJ 2023;11:e14556
PeerJ 2023;11:e14556
Aquaporin-7 Facilitates Proliferation and Adipogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Regulating Hydrogen Peroxide Transport.
Ma Y, Zhang J, Li Y, Hu H, Ye Q, Yang C, Yang L, Zhang B, Ma T
Stem cell reviews and reports 2023 Oct;19(7):2378-2390
Stem cell reviews and reports 2023 Oct;19(7):2378-2390
Phosphorylated YBX2 is stabilized to promote glycolysis in brown adipocytes.
Zhao Q, Yu C, Xu X, Jin W, Zhang Z, Huang H, Gao Y, Pan D
iScience 2023 Oct 20;26(10):108091
iScience 2023 Oct 20;26(10):108091
Methylation of lncSHGL promotes adipocyte differentiation by regulating miR-149/Mospd3 axis.
Huang X, Liu X, Lin J
Cell cycle (Georgetown, Tex.) 2023 Nov;22(21-22):2361-2380
Cell cycle (Georgetown, Tex.) 2023 Nov;22(21-22):2361-2380
TET2 is recruited by CREB to promote Cebpb, Cebpa, and Pparg transcription by facilitating hydroxymethylation during adipocyte differentiation.
Liu Y, He T, Li Z, Sun Z, Wang S, Shen H, Hou L, Li S, Wei Y, Zhuo B, Li S, Zhou C, Guo H, Zhang R, Li B
iScience 2023 Nov 17;26(11):108312
iScience 2023 Nov 17;26(11):108312
Targeting FABP4 in elderly mice rejuvenates liver metabolism and ameliorates aging-associated metabolic disorders.
Lv J, Hu Y, Li L, He Y, Wang J, Guo N, Fang Y, Chen Q, Cai C, Tong J, Tang L, Wang Z
Metabolism: clinical and experimental 2023 May;142:155528
Metabolism: clinical and experimental 2023 May;142:155528
Apolipoprotein E facilitates titanium implant osseointegration by regulating osteogenesis-lipogenesis balance.
Wang YN, Yu L, Wang T, Liu S
International journal of biological macromolecules 2023 May 1;236:123998
International journal of biological macromolecules 2023 May 1;236:123998
Reduction of NADPH oxidase 4 in adipocytes contributes to the anti-obesity effect of dihydroartemisinin.
Hua H, Wu M, Wu T, Ji Y, Jin L, Du Y, Zhang Y, Huang S, Zhang A, Ding G, Liu Q, Jia Z
Heliyon 2023 Mar;9(3):e14028
Heliyon 2023 Mar;9(3):e14028
Bone marrow mesenchymal stem cell-derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway.
Shi H, Hao X, Sun Y, Zhang H, Zhao Y, Wang B, Lu J, Hou W, Yan Y, Yu X, Xue L, Luo X, Wang H
FEBS open bio 2023 Jun;13(6):1015-1026
FEBS open bio 2023 Jun;13(6):1015-1026
Adipocytes promote pancreatic cancer migration and invasion through fatty acid metabolic reprogramming.
Cai Z, Li Y, Ma M, Wang L, Wang H, Liu M, Jiang C
Oncology reports 2023 Jul;50(1)
Oncology reports 2023 Jul;50(1)
Intra-tumoral infiltration of adipocyte facilitates the activation of antitumor immune response in pancreatic ductal adenocarcinoma.
Liu X, Liu J, Xu J, Zhang B, Wei M, Li J, Xu H, Yu X, Wang W, Shi S
Translational oncology 2023 Jan;27:101561
Translational oncology 2023 Jan;27:101561
Caveolae-associated protein 3 promotes adipogenic differentiation of porcine preadipocytes by promoting extracellular signal-regulated kinase phosphorylation.
Shi M, Yang S, Huang X, Wang S, Li W, Yun J, Lu C, Yang Y, Cai C, Gao P, Guo X, Li B, Cao G
Animal science journal = Nihon chikusan Gakkaiho 2023 Jan-Dec;94(1):e13822
Animal science journal = Nihon chikusan Gakkaiho 2023 Jan-Dec;94(1):e13822
circINSR Inhibits Adipogenic Differentiation of Adipose-Derived Stromal Vascular Fractions through the miR-152/MEOX2 Axis in Sheep.
Zhao B, Zhang H, Zhao D, Liang Y, Qiao L, Liu J, Pan Y, Yang K, Liu W
International journal of molecular sciences 2023 Feb 9;24(4)
International journal of molecular sciences 2023 Feb 9;24(4)
Oridonin attenuates atherosclerosis by inhibiting foam macrophage formation and inflammation through FABP4/PPARγ signalling.
Zhang M, Hou L, Tang W, Lei W, Lin H, Wang Y, Long H, Lin S, Chen Z, Wang G, Zhao G
Journal of cellular and molecular medicine 2023 Dec;27(24):4155-4170
Journal of cellular and molecular medicine 2023 Dec;27(24):4155-4170
LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs.
Jiang W, Chen Y, Sun M, Huang X, Zhang H, Fu Z, Wang J, Zhang S, Lian C, Tang B, Xiang D, Wang Y, Zhang Y, Jian C, Yang C, Zhang J, Zhang D, Chen T, Zhang J
Cell reports 2023 Aug 29;42(8):112969
Cell reports 2023 Aug 29;42(8):112969
A cell-autonomous mechanism regulates BCAA catabolism in white adipocytes and systemic metabolic balance.
Aguillard AM, Tzeng J, Ferrer I, Tam BT, Lorenzo DN
bioRxiv : the preprint server for biology 2023 Aug 1;
bioRxiv : the preprint server for biology 2023 Aug 1;
Inhibition of Fatty Acid β-Oxidation by Fatty Acid Binding Protein 4 Induces Ferroptosis in HK2 Cells Under High Glucose Conditions.
Chen J, Wu K, Lei Y, Huang M, Cheng L, Guan H, Lin J, Zhong M, Wang X, Zheng Z
Endocrinology and metabolism (Seoul, Korea) 2023 Apr;38(2):226-244
Endocrinology and metabolism (Seoul, Korea) 2023 Apr;38(2):226-244
Tax1 binding protein 3 regulates osteogenic and adipogenic differentiation through inactivating Wnt/β-catenin signalling.
Wang Y, Gan Y, Dong Y, Zhou J, Zhu E, Yuan H, Li X, Wang B
Journal of cellular and molecular medicine 2023 Apr;27(7):950-961
Journal of cellular and molecular medicine 2023 Apr;27(7):950-961
Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity.
He T, Wang S, Li S, Shen H, Hou L, Liu Y, Wei Y, Xie F, Zhang Z, Zhao Z, Mo C, Guo H, Huang Q, Zhang R, Shen D, Li B
iScience 2023 Apr 21;26(4):106289
iScience 2023 Apr 21;26(4):106289
Upregulated estrogen receptors impairs myogenesis and elevates adipogenesis related factor levels in the paravertebral muscles of patients with idiopathic scoliosis.
Shu Q, Yang G, Tang M, Guo C, Zhang H, Li J
Biochemical and biophysical research communications 2023 Apr 16;652:22-30
Biochemical and biophysical research communications 2023 Apr 16;652:22-30
Tumor Microenvironment Heterogeneity-Based Score System Predicts Clinical Prognosis and Response to Immune Checkpoint Blockade in Multiple Colorectal Cancer Cohorts.
Wang H, Li Z, Ou S, Song Y, Luo K, Guan Z, Zhao L, Huang R, Yu S
Frontiers in molecular biosciences 2022;9:884839
Frontiers in molecular biosciences 2022;9:884839
Proteomic profiling reveals the potential mechanisms and regulatory targets of sirtuin 4 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's mouse model.
Weng H, Song W, Fu K, Guan Y, Cai G, Huang E, Chen X, Zou H, Ye Q
Frontiers in neuroscience 2022;16:1035444
Frontiers in neuroscience 2022;16:1035444
Knockdown of CDC20 promotes adipogenesis of bone marrow-derived stem cells by modulating β-catenin.
Du Y, Liu Y, Zhou Y, Zhang P
Stem cell research & therapy 2022 Sep 2;13(1):443
Stem cell research & therapy 2022 Sep 2;13(1):443
Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension.
Lee MH, Sanders L, Kumar R, Hernandez-Saavedra D, Yun X, Ford JA, Perez MJ, Mickael C, Gandjeva A, Koyanagi DE, Harral JW, Irwin DC, Kassa B, Eckel RH, Shimoda LA, Graham BB, Tuder RM
American journal of physiology. Lung cellular and molecular physiology 2022 Sep 1;323(3):L355-L371
American journal of physiology. Lung cellular and molecular physiology 2022 Sep 1;323(3):L355-L371
Vasorin contributes to lung injury via FABP4-mediated inflammation.
Guo X, Sun J, Liang J, Zhu S, Zhang M, Yang L, Huang X, Xue K, Mo Z, Wen S, Hu B, Liu J, Ouyang Y, He M
Molecular biology reports 2022 Oct;49(10):9335-9344
Molecular biology reports 2022 Oct;49(10):9335-9344
Dysregulated adipose tissue expansion and impaired adipogenesis in Prader-Willi syndrome children before obesity-onset.
Chao Y, Gao L, Wang X, Cai Y, Shu Y, Zou X, Qin Y, Hu C, Dai Y, Zhu M, Shen Z, Zou C
Metabolism: clinical and experimental 2022 Nov;136:155295
Metabolism: clinical and experimental 2022 Nov;136:155295
DEPTOR exacerbates bone-fat imbalance in osteoporosis by transcriptionally modulating BMSC differentiation.
Ouyang Z, Kang D, Li K, Liang G, Liu Z, Mai Q, Chen Q, Yao C, Wei R, Tan X, Bai X, Huang B, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113164
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113164
Long noncoding RNA ZFAS1 suppresses osteogenic differentiation of bone marrow-derived mesenchymal stem cells by upregulating miR-499-EPHA5 axis.
Wu J, Lin T, Gao Y, Li X, Yang C, Zhang K, Wang C, Zhou X
Molecular and cellular endocrinology 2022 Jan 1;539:111490
Molecular and cellular endocrinology 2022 Jan 1;539:111490
N-myc downstream regulated gene 1 suppresses osteoblast differentiation through inactivating Wnt/β-catenin signaling.
Shi X, Cen Y, Shan L, Tian L, Zhu E, Yuan H, Li X, Liu Y, Wang B
Stem cell research & therapy 2022 Feb 4;13(1):53
Stem cell research & therapy 2022 Feb 4;13(1):53
miR-669a-5p promotes adipogenic differentiation and induces browning in preadipocytes.
Tan X, Zhu T, Zhang L, Fu L, Hu Y, Li H, Li C, Zhang J, Liang B, Liu J
Adipocyte 2022 Dec;11(1):120-132
Adipocyte 2022 Dec;11(1):120-132
Contribution of Oxidative Stress Induced by Sonodynamic Therapy to the Calcium Homeostasis Imbalance Enhances Macrophage Infiltration in Glioma Cells.
Chen L, Yan Y, Kong F, Wang J, Zeng J, Fang Z, Wang Z, Liu Z, Liu F
Cancers 2022 Apr 18;14(8)
Cancers 2022 Apr 18;14(8)
Fatty acid-binding protein 4 is a therapeutic target for septic acute kidney injury by regulating inflammatory response and cell apoptosis.
Wang B, Xu J, Ren Q, Cheng L, Guo F, Liang Y, Yang L, Tan Z, Fu P, Ma L
Cell death & disease 2022 Apr 11;13(4):333
Cell death & disease 2022 Apr 11;13(4):333
Quantitative proteomic analysis identified differentially expressed proteins with tail/rump fat deposition in Chinese thin- and fat-tailed lambs.
Han J, Guo T, Yue Y, Lu Z, Liu J, Yuan C, Niu C, Yang M, Yang B
PloS one 2021;16(2):e0246279
PloS one 2021;16(2):e0246279
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells.
Wu R, Wang H, Huangfu J, Xiao R
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2103-2110
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2103-2110
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.
Zou M, Chen Y, Zheng Z, Sheng S, Jia Y, Wang X, Ren S, Yang Y, Li X, Dong W, Guan M, Zhang Q, Xue Y
Frontiers in pharmacology 2021;12:741087
Frontiers in pharmacology 2021;12:741087
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters.
Jiang MJ, Li L, Huang WF, Su J, Li YH, Qu XS, Fan LL
Journal of natural medicines 2021 Sep;75(4):884-892
Journal of natural medicines 2021 Sep;75(4):884-892
High-mobility group AT-Hook 1 mediates the role of nuclear factor I/X in osteogenic differentiation through activating canonical Wnt signaling.
Wu X, Wang X, Shan L, Zhou J, Zhang X, Zhu E, Yuan H, Wang B
Stem cells (Dayton, Ohio) 2021 Oct;39(10):1349-1361
Stem cells (Dayton, Ohio) 2021 Oct;39(10):1349-1361
Single-cell RNA sequencing analysis to characterize cells and gene expression landscapes in atrial septal defect.
Wang Z, Wang H, Zhang Y, Yu F, Yu L, Zhang C
Journal of cellular and molecular medicine 2021 Oct;25(20):9660-9673
Journal of cellular and molecular medicine 2021 Oct;25(20):9660-9673
FABP4 is an independent risk factor for lymph node metastasis and poor prognosis in patients with cervical cancer.
Li G, Wu Q, Gong L, Xu X, Cai J, Xu L, Zeng Y, He X, Wang Z
Cancer cell international 2021 Oct 26;21(1):568
Cancer cell international 2021 Oct 26;21(1):568
Expression of fatty acid-binding protein-4 in gastrointestinal stromal tumors and its significance for prognosis.
Zang WJ, Wang ZN, Hu YL, Huang H, Ma P
Journal of clinical laboratory analysis 2021 Nov;35(11):e24017
Journal of clinical laboratory analysis 2021 Nov;35(11):e24017
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Song M, Zhang S, Tao Z, Li J, Shi Y, Xiong Y, Zhang W, Liu C, Chen S
Biomaterials 2021 Nov;278:121183
Biomaterials 2021 Nov;278:121183
SNHG16/miR-485-5p/BMP7 axis modulates osteogenic differentiation of human bone marrow-derived mesenchymal stem cells.
Asila A, Yang X, Kaisaer Y, Ma L
The journal of gene medicine 2021 Mar;23(3):e3296
The journal of gene medicine 2021 Mar;23(3):e3296
Effect of Notch pathway on lipid accumulation induced by mono-2-ethylhexyl phthalate on 3T3-L1 cells.
Qi W, Xu Q, Xu Y, Wang Z, Yang L, Guo S, Shi Y, Zhao T, Zhou L, Ye L
Ecotoxicology and environmental safety 2021 Jan 15;208:111472
Ecotoxicology and environmental safety 2021 Jan 15;208:111472
Maternal high-fat-diet exposure is associated with elevated blood pressure and sustained increased leptin levels through epigenetic memory in offspring.
Lin XH, Gao L, Tian S, Klausen C, Guo MX, Gao Q, Liu ME, Wang H, Wu DD, Zhou CL, Yang J, Meng Y, Liu Y, Xu GF, Tan YJ, Ullah K, Zhu YM, Fraser WD, Sheng JZ, Leung PCK, Muglia LJ, Wu YT, Huang HF
Scientific reports 2021 Jan 11;11(1):316
Scientific reports 2021 Jan 11;11(1):316
Effects of the FABP4 gene on steroid hormone secretion in goose ovarian granulosa cells.
Fan R, Cao Z, Chen M, Wang H, Liu M, Gao M, Luan X
British poultry science 2021 Feb;62(1):81-91
British poultry science 2021 Feb;62(1):81-91
Histone Deacetylase Inhibitor SAHA Induces Expression of Fatty Acid-Binding Protein 4 and Inhibits Replication of Human Cytomegalovirus.
Liu Z, Xuan B, Tang S, Qian Z
Virologica Sinica 2021 Dec;36(6):1352-1362
Virologica Sinica 2021 Dec;36(6):1352-1362
IL-20 is involved in obesity by modulation of adipogenesis and macrophage dysregulation.
Hsu YH, Wu CH, Chiu CJ, Chen WT, Chang YC, Wabitsch M, Chang MS
Immunology 2021 Dec;164(4):817-833
Immunology 2021 Dec;164(4):817-833
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Guo H, Yang Y, Qiao Y, He J, Yao W, Zheng W
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
FTO inhibits UPR(mt)-induced apoptosis by activating JAK2/STAT3 pathway and reducing m6A level in adipocytes.
Shen Z, Liu P, Sun Q, Li Y, Acharya R, Li X, Sun C
Apoptosis : an international journal on programmed cell death 2021 Aug;26(7-8):474-487
Apoptosis : an international journal on programmed cell death 2021 Aug;26(7-8):474-487
Expression and enhancement of FABP4 in septoclasts of the growth plate in FABP5-deficient mouse tibiae.
Bando Y, Tokuda N, Ogasawara Y, Onozawa G, Nagasaka A, Sakiyama K, Owada Y, Amano O
Histochemistry and cell biology 2021 Apr;155(4):439-449
Histochemistry and cell biology 2021 Apr;155(4):439-449
Insulin receptor substrate-1 inhibits high-fat diet-induced obesity by browning of white adipose tissue through miR-503.
Man XF, Hu N, Tan SW, Tang HN, Guo Y, Tang CY, Liu YQ, Tang J, Zhou CL, Wang F, Zhou HD
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12308-12323
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12308-12323
Lysophosphatidic acid receptor 4 regulates osteogenic and adipogenic differentiation of progenitor cells via inactivation of RhoA/ROCK1/β-catenin signaling.
Xie Y, Wang X, Wu X, Tian L, Zhou J, Li X, Wang B
Stem cells (Dayton, Ohio) 2020 Mar;38(3):451-463
Stem cells (Dayton, Ohio) 2020 Mar;38(3):451-463
Histone demethylase KDM4A regulates adipogenic and osteogenic differentiation via epigenetic regulation of C/EBPα and canonical Wnt signaling.
Qi Q, Wang Y, Wang X, Yang J, Xie Y, Zhou J, Li X, Wang B
Cellular and molecular life sciences : CMLS 2020 Jun;77(12):2407-2421
Cellular and molecular life sciences : CMLS 2020 Jun;77(12):2407-2421
miR-196b-5p controls adipocyte differentiation and lipogenesis through regulating mTORC1 and TGF-β signaling.
Shi Y, Li F, Wang S, Wang C, Xie Y, Zhou J, Li X, Wang B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9207-9222
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9207-9222
m(6)A mRNA methylation controls autophagy and adipogenesis by targeting Atg5 and Atg7.
Wang X, Wu R, Liu Y, Zhao Y, Bi Z, Yao Y, Liu Q, Shi H, Wang F, Wang Y
Autophagy 2020 Jul;16(7):1221-1235
Autophagy 2020 Jul;16(7):1221-1235
Effects of di (2-ethylhexyl) phthalate and high-fat diet on lipid metabolism in rats by JAK2/STAT5.
Zhang Y, Zhou L, Zhang Z, Xu Q, Han X, Zhao Y, Song X, Zhao T, Ye L
Environmental science and pollution research international 2020 Feb;27(4):3837-3848
Environmental science and pollution research international 2020 Feb;27(4):3837-3848
PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission.
Guo J, Ren R, Yao X, Ye Y, Sun K, Lin J, Wang G, Guo F, Xiao J, Xu T
Aging 2020 Feb 25;12(4):3976-3992
Aging 2020 Feb 25;12(4):3976-3992
Breed difference and regulatory role of CRTC3 in porcine intramuscular adipocyte.
Liu J, Nong Q, Wang J, Chen W, Xu Z, You W, Xie J, Wang Y, Shan T
Animal genetics 2020 Aug;51(4):521-530
Animal genetics 2020 Aug;51(4):521-530
miR-27a is an important adipogenesis regulator associated with differential lipid accumulation between intramuscular and subcutaneous adipose tissues of sheep.
Deng K, Ren C, Fan Y, Liu Z, Zhang G, Zhang Y, You P, Wang F
Domestic animal endocrinology 2020 Apr;71:106393
Domestic animal endocrinology 2020 Apr;71:106393
IL-29 promoted obesity-induced inflammation and insulin resistance.
Lin TY, Chiu CJ, Kuan CH, Chen FH, Shen YC, Wu CH, Hsu YH
Cellular & molecular immunology 2020 Apr;17(4):369-379
Cellular & molecular immunology 2020 Apr;17(4):369-379
A novel Sprouty4-ERK1/2-Wnt/β-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation.
Tian L, Xiao H, Li M, Wu X, Xie Y, Zhou J, Zhang X, Wang B
Metabolism: clinical and experimental 2020 Apr;105:154189
Metabolism: clinical and experimental 2020 Apr;105:154189
Cerasus humilis Cherry Polyphenol Reduces High-Fat Diet-Induced Obesity in C57BL/6 Mice by Mitigating Fat Deposition, Inflammation, and Oxidation.
Liu S, Chang X, Yu J, Xu W
Journal of agricultural and food chemistry 2020 Apr 15;68(15):4424-4436
Journal of agricultural and food chemistry 2020 Apr 15;68(15):4424-4436
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
Wang S, Yao Y, Wang X, Zheng G, Ouyang W, Chen W
American journal of cancer research 2019;9(10):2140-2155
American journal of cancer research 2019;9(10):2140-2155
Significant Role of Dicer and miR-223 in Adipose Tissue of Polycystic Ovary Syndrome Patients.
Qin L, Chen J, Tang L, Zuo T, Chen H, Gao R, Xu W
BioMed research international 2019;2019:9193236
BioMed research international 2019;2019:9193236
A Novel Regulatory Circuit "C/EBPα/miR-20a-5p/TOB2" Regulates Adipogenesis and Lipogenesis.
Zhou J, Yang J, Wang X, Li M, Li F, Zhu E, Li X, Li X, Wang B
Frontiers in endocrinology 2019;10:894
Frontiers in endocrinology 2019;10:894
A novel long noncoding RNA PGC1β-OT1 regulates adipocyte and osteoblast differentiation through antagonizing miR-148a-3p.
Yuan H, Xu X, Feng X, Zhu E, Zhou J, Wang G, Tian L, Wang B
Cell death and differentiation 2019 Oct;26(10):2029-2045
Cell death and differentiation 2019 Oct;26(10):2029-2045
Aspirin inhibits adipogenesis of tendon stem cells and lipids accumulation in rat injury tendon through regulating PTEN/PI3K/AKT signalling.
Wang Y, He G, Wang F, Zhang C, Ge Z, Zheng X, Deng H, Yuan C, Zhou B, Tao X, Zhang J, Tang K
Journal of cellular and molecular medicine 2019 Nov;23(11):7535-7544
Journal of cellular and molecular medicine 2019 Nov;23(11):7535-7544
Glucocorticoid Enhanced the Expression of Ski in Osteonecrosis of Femoral Head: The Effect on Adipogenesis of Rabbit BMSCs.
Zhao X, Wei Z, Li D, Yang Z, Tian M, Kang P
Calcified tissue international 2019 Nov;105(5):506-517
Calcified tissue international 2019 Nov;105(5):506-517
Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.
Zhang Y, Wang S, Zhao T, Yang L, Guo S, Shi Y, Zhang X, Zhou L, Ye L
Ecotoxicology and environmental safety 2019 Nov 30;184:109611
Ecotoxicology and environmental safety 2019 Nov 30;184:109611
Cancer‑associated adipocytes exhibit distinct phenotypes and facilitate tumor progression in pancreatic cancer.
Cai Z, Liang Y, Xing C, Wang H, Hu P, Li J, Huang H, Wang W, Jiang C
Oncology reports 2019 Dec;42(6):2537-2549
Oncology reports 2019 Dec;42(6):2537-2549
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.
Li TY, Song L, Sun Y, Li J, Yi C, Lam SM, Xu D, Zhou L, Li X, Yang Y, Zhang CS, Xie C, Huang X, Shui G, Lin SY, Reue K, Lin SC
Nature communications 2018 May 15;9(1):1916
Nature communications 2018 May 15;9(1):1916
Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling.
Yang Y, Qi Q, Wang Y, Shi Y, Yang W, Cen Y, Zhu E, Li X, Chen D, Wang B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun;32(6):3096-3107
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun;32(6):3096-3107
The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.
Liu G, Wang K, Kuang S, Cao R, Bao L, Liu R, Liu H, Sun C
Cell death & disease 2018 Jun 7;9(6):689
Cell death & disease 2018 Jun 7;9(6):689
Comparative proteomic analysis of ovaries from Huoyan geese between pre-laying and laying periods using an iTRAQ-based approach.
Cao Z, Meng B, Fan R, Liu M, Gao M, Xing Z, Luan X
Poultry science 2018 Jun 1;97(6):2170-2182
Poultry science 2018 Jun 1;97(6):2170-2182
IL-1α inhibits proliferation and adipogenic differentiation of human adipose-derived mesenchymal stem cells through NF-κB- and ERK1/2-mediated proinflammatory cytokines.
Sun X, Zou T, Zuo C, Zhang M, Shi B, Jiang Z, Cui H, Liao X, Li X, Tang Y, Liu Y, Liu X
Cell biology international 2018 Jul;42(7):794-803
Cell biology international 2018 Jul;42(7):794-803
Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics for the investigation of the effect of Hugan Qingzhi on non-alcoholic fatty liver disease in rats.
Yao X, Xia F, Tang W, Xiao C, Yang M, Zhou B
Journal of ethnopharmacology 2018 Feb 15;212:208-215
Journal of ethnopharmacology 2018 Feb 15;212:208-215
Pygo2 Regulates Adiposity and Glucose Homeostasis via β-Catenin-Axin2-GSK3β Signaling Pathway.
Xie YY, Mo CL, Cai YH, Wang WJ, Hong XX, Zhang KK, Liu QF, Liu YJ, Hong JJ, He T, Zheng ZZ, Mo W, Li BA
Diabetes 2018 Dec;67(12):2569-2584
Diabetes 2018 Dec;67(12):2569-2584
miR-128-3p regulates 3T3-L1 adipogenesis and lipolysis by targeting Pparg and Sertad2.
Chen C, Deng Y, Hu X, Ren H, Zhu J, Fu S, Xie J, Peng Y
Journal of physiology and biochemistry 2018 Aug;74(3):381-393
Journal of physiology and biochemistry 2018 Aug;74(3):381-393
miR-148a-3p regulates adipocyte and osteoblast differentiation by targeting lysine-specific demethylase 6b.
Tian L, Zheng F, Li Z, Wang H, Yuan H, Zhang X, Ma Z, Li X, Gao X, Wang B
Gene 2017 Sep 5;627:32-39
Gene 2017 Sep 5;627:32-39
Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins.
Charles KN, Li MD, Engin F, Arruda AP, Inouye K, Hotamisligil GS
Cell reports 2017 Oct 10;21(2):393-402
Cell reports 2017 Oct 10;21(2):393-402
Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity.
Gao Y, Li J, Xu X, Wang S, Yang Y, Zhou J, Zhang L, Zheng F, Li X, Wang B
International journal of obesity (2005) 2017 May;41(5):729-738
International journal of obesity (2005) 2017 May;41(5):729-738
Iron overload inhibits osteogenic commitment and differentiation of mesenchymal stem cells via the induction of ferritin.
Balogh E, Tolnai E, Nagy B Jr, Nagy B, Balla G, Balla J, Jeney V
Biochimica et biophysica acta 2016 Sep;1862(9):1640-9
Biochimica et biophysica acta 2016 Sep;1862(9):1640-9
Quantitative proteomic analysis reveals that anti-cancer effects of selenium-binding protein 1 in vivo are associated with metabolic pathways.
Ying Q, Ansong E, Diamond AM, Lu Z, Yang W, Bie X
PloS one 2015;10(5):e0126285
PloS one 2015;10(5):e0126285
miR-223 Regulates Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells Through a C/EBPs/miR-223/FGFR2 Regulatory Feedback Loop.
Guan X, Gao Y, Zhou J, Wang J, Zheng F, Guo F, Chang A, Li X, Wang B
Stem cells (Dayton, Ohio) 2015 May;33(5):1589-600
Stem cells (Dayton, Ohio) 2015 May;33(5):1589-600
Nuclear envelope proteins Nesprin2 and LaminA regulate proliferation and apoptosis of vascular endothelial cells in response to shear stress.
Han Y, Wang L, Yao QP, Zhang P, Liu B, Wang GL, Shen BR, Cheng B, Wang Y, Jiang ZL, Qi YX
Biochimica et biophysica acta 2015 May;1853(5):1165-73
Biochimica et biophysica acta 2015 May;1853(5):1165-73
miR-204-5p promotes the adipogenic differentiation of human adipose-derived mesenchymal stem cells by modulating DVL3 expression and suppressing Wnt/β-catenin signaling.
He H, Chen K, Wang F, Zhao L, Wan X, Wang L, Mo Z
International journal of molecular medicine 2015 Jun;35(6):1587-95
International journal of molecular medicine 2015 Jun;35(6):1587-95
miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis.
Chen K, He H, Xie Y, Zhao L, Zhao S, Wan X, Yang W, Mo Z
Scientific reports 2015 Jul 7;5:11909
Scientific reports 2015 Jul 7;5:11909
miR-140-5p regulates adipocyte differentiation by targeting transforming growth factor-β signaling.
Zhang X, Chang A, Li Y, Gao Y, Wang H, Ma Z, Li X, Wang B
Scientific reports 2015 Dec 11;5:18118
Scientific reports 2015 Dec 11;5:18118
miR-30e reciprocally regulates the differentiation of adipocytes and osteoblasts by directly targeting low-density lipoprotein receptor-related protein 6.
Wang J, Guan X, Guo F, Zhou J, Chang A, Sun B, Cai Y, Ma Z, Dai C, Li X, Wang B
Cell death & disease 2013 Oct 10;4(10):e845
Cell death & disease 2013 Oct 10;4(10):e845
Rosiglitazone disrupts endosteal bone formation during distraction osteogenesis by local adipocytic infiltration.
Liu L, Aronson J, Lecka-Czernik B
Bone 2013 Jan;52(1):247-58
Bone 2013 Jan;52(1):247-58
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 12802-1-AP(FABP4 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 12802-1-AP(FABP4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The FABP4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FABP4. This antibody recognizes human, mouse, rat antigen. The FABP4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.