Tissue expression
Cell line expression
Protein structure
TFIP11
Tuftelin interacting protein 11DKFZP434B194, Spp382, TIP39
This gene encodes a protein component of the spliceosome that promotes the release of the lariat-intron during late-stage splicing through the recruitment of a pre-mRNA splicing factor called DEAH-box helicase 15. The encoded protein contains a G-patch domain, a hallmark of RNA-processing proteins, that binds DEAH-box helicase 15. This protein contains an atypical nuclear localization sequence as well as a nuclear speckle-targeting sequence, enabling it to localize to distinct speckled regions within the cell nucleus. Polymorphisms in this gene are associated with dental caries suggesting a role in amelogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Top validated antibodies |
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Proteintech Group | ![]() |
Monoclonal |
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NovoPro Bioscience Inc. | ![]() |
Monoclonal |
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Invitrogen Antibodies | ![]() |
Monoclonal |
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Novus Biologicals | ![]() |
Polyclonal |
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Bethyl Laboratories | ![]() |
Polyclonal |
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