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Protein structure
REST
RE1 silencing transcription factorDFNA27, NRSF, XBR
This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2018]
Top validated antibodies |
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| Invitrogen Antibodies |  MA5-24606 |
2 references | Monoclonal |
WB
ICC
IHC
ChIP
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| Proteintech Group | 22242-1-AP |
12 references | Polyclonal |
WB
EL
IP
IHC
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| Novus Biologicals | NB100-756 |
1 references | Polyclonal |
WB
IP
IHC
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| antibodies-online | ABIN152175 |
1 references | Polyclonal |
WB
ICC
IP
IHC
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| NovoPro Bioscience Inc. | 114693 |
Polyclonal |
WB
EL
IP
|
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