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PHLPP1
PH domain and leucine rich repeat protein phosphatase 1KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]
Top validated antibodies |
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| Proteintech Group |  22789-1-AP |
18 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 22789-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| NovoPro Bioscience Inc. | 113825 |
Polyclonal |
WB
EL
ICC
IP
IHC
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| Wuhan Fine Biotech Co., Ltd. | FNab06398 |
Polyclonal |
WB
EL
ICC
IP
IHC
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| antibodies-online | ABIN2492557 |
Polyclonal |
WB
EL
IHC
FC
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