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CHAT
Choline O-acetyltransferaseThis gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]
Top validated antibodies |
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| Proteintech Group |  20747-1-AP |
23 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | PA5-29653 |
3 references | Polyclonal |
WB
ICC
IHC
OA
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| Novus Biologicals | NB110-89724 |
2 references | Polyclonal |
WB
ICC
IHC
OA
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| NSJ Bioreagents | RQ6043 |
Polyclonal |
WB
EL
ICC
IHC
FC
|
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| Boster Biological Technology | A01192-4 |
Polyclonal |
WB
EL
ICC
IHC
FC
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