Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 23762-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- RSK2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RSK2 antibody (Cat. #23762-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A short peptide LINC00665_18aa encoded by lncRNA LINC00665 suppresses the proliferation and migration of osteosarcoma cells through the regulation of the CREB1/RPS6KA3 interaction.
PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2.
β-Trcp and CK1δ-mediated degradation of LZTS2 activates PI3K/AKT signaling to drive tumorigenesis and metastasis in hepatocellular carcinoma.
FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM.
S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer.
β-Trcp ubiquitin ligase and RSK2 kinase-mediated degradation of FOXN2 promotes tumorigenesis and radioresistance in lung cancer.
MicroRNA181c inhibits prostate cancer cell growth and invasion by targeting multiple ERK signaling pathway components.
DHPAC, a novel synthetic microtubule destabilizing agent, possess high anti-tumor activity in vincristine-resistant oral epidermoid carcinoma in vitro and in vivo.
Pan J, Liu M, Duan X, Wang D
PloS one 2023;18(6):e0286422
PloS one 2023;18(6):e0286422
PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2.
Chen Q, Jin J, Guo W, Tang Z, Luo Y, Ying Y, Lin H, Luo Z
International journal of molecular sciences 2022 Aug 8;23(15)
International journal of molecular sciences 2022 Aug 8;23(15)
β-Trcp and CK1δ-mediated degradation of LZTS2 activates PI3K/AKT signaling to drive tumorigenesis and metastasis in hepatocellular carcinoma.
Lu Y, Li X, Liu H, Xue J, Zeng Z, Dong X, Zhang T, Wu G, Yang K, Xu S
Oncogene 2021 Feb;40(7):1269-1283
Oncogene 2021 Feb;40(7):1269-1283
FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM.
Watanabe D, Nogami A, Okada K, Akiyama H, Umezawa Y, Miura O
Cancers 2019 Nov 20;11(12)
Cancers 2019 Nov 20;11(12)
S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer.
Huang Y, Hu K, Zhang S, Dong X, Yin Z, Meng R, Zhao Y, Dai X, Zhang T, Yang K, Liu L, Huang K, Shi S, Zhang Y, Chen J, Wu G, Xu S
Theranostics 2018;8(5):1286-1300
Theranostics 2018;8(5):1286-1300
β-Trcp ubiquitin ligase and RSK2 kinase-mediated degradation of FOXN2 promotes tumorigenesis and radioresistance in lung cancer.
Ma J, Lu Y, Zhang S, Li Y, Huang J, Yin Z, Ren J, Huang K, Liu L, Yang K, Wu G, Xu S
Cell death and differentiation 2018 Aug;25(8):1473-1485
Cell death and differentiation 2018 Aug;25(8):1473-1485
MicroRNA181c inhibits prostate cancer cell growth and invasion by targeting multiple ERK signaling pathway components.
Su Z, Zhang M, Xu M, Li X, Tan J, Xu Y, Pan X, Chen N, Chen X, Zhou Q
The Prostate 2018 Apr;78(5):343-352
The Prostate 2018 Apr;78(5):343-352
DHPAC, a novel synthetic microtubule destabilizing agent, possess high anti-tumor activity in vincristine-resistant oral epidermoid carcinoma in vitro and in vivo.
Zhang Y, Gong FL, Lu ZN, Wang HY, Cheng YN, Liu ZP, Yu LG, Zhang HH, Guo XL
The international journal of biochemistry & cell biology 2017 Dec;93:1-11
The international journal of biochemistry & cell biology 2017 Dec;93:1-11
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 23762-1-AP(RPS6KA3 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RSK2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human RSK2. This antibody recognizes human, mouse antigen. The RSK2 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.