GRM7

gene product
GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87
L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
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Invitrogen Antibodies
11 antibodies
antibodies-online
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Novus Biologicals
16 antibodies
OriGene
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LifeSpan BioSciences, Inc.
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Biorbyt
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Aviva Systems Biology
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NovoPro Bioscience Inc.
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Bioworld Technology, Inc
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5 antibodies
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Abbkine Scientific Co.Ltd.
2 antibodies
Antibodies.com
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
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6 antibodies
R&D Systems
8 antibodies
ProSci
3 antibodies
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1 antibody
United States Biological
40 antibodies
Creative Biolabs
7 antibodies
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8 antibodies
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1 antibody
MyBioSource
5 antibodies
RayBiotech, Inc.
5 antibodies
EMD Millipore
2 antibodies
Creative Diagnostics
1 antibody
GenWay
4 antibodies
Sigma-Aldrich
2 antibodies