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- References [19]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12191-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12191-1-AP, RRID:AB_889392
- Product name
- Endothelin 1 antibody
- Antibody type
- Polyclonal
- Description
- Endothelin 1 antibody (Cat. #12191-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references REXO2 up-regulation is positively correlated with poor prognosis and tumor immune infiltration in hepatocellular carcinoma.
Post-injury Inhibition of Endothelin-1 Dependent Renal Vasoregulation Mitigates Rhabdomyolysis-Induced Acute Kidney Injury.
Histopathological Evaluation of Pulmonary Thromboendarterectomy Specimens of Chronic Thromboembolic Pulmonary Hypertension.
Exercise protects aged mice against coronary endothelial senescence via FUNDC1-dependent mitophagy.
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4.
Endothelin-1 production via placental (pro)renin receptor in a mouse model of preeclampsia.
Different exercise training intensities prevent type 2 diabetes mellitus-induced myocardial injury in male mice.
The effect and mechanism of excessive iodine on the endothelial function of human umbilical vein endothelial cells.
Ufl1 deficiency causes skin pigmentation by up-regulation of Endothelin-1.
miR-351 promotes atherosclerosis in diabetes by inhibiting the ITGB3/PIK3R1/Akt pathway and induces endothelial cell injury and lipid accumulation.
Macrophage-derived exosomal miR-4532 promotes endothelial cells injury by targeting SP1 and NF-κB P65 signalling activation.
Systems analysis identifies endothelin 1 axis blockade for enhancing the anti-tumor effect of multikinase inhibitor.
Curcumin improves the function of umbilical vein endothelial cells by inhibiting H(2)O(2)‑induced pyroptosis.
Roquin2 suppresses breast cancer progression by inhibiting tumor angiogenesis via selectively destabilizing proangiogenic factors mRNA.
Cadmium exposure induces endothelial dysfunction via disturbing lipid metabolism in human microvascular endothelial cells.
The lncRNA MALAT1 participates in regulating coronary slow flow endothelial dysfunction through the miR-181b-5p-MEF2A-ET-1 axis.
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Blocking mitochondrial cyclophilin D ameliorates TSH-impaired defensive barrier of artery.
Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes.
Zhang T, Zhang R, Zhang Z, Li D, Guo X, Zhang Z, Zhu X, Tan S
International immunopharmacology 2024 Mar 30;130:111740
International immunopharmacology 2024 Mar 30;130:111740
Post-injury Inhibition of Endothelin-1 Dependent Renal Vasoregulation Mitigates Rhabdomyolysis-Induced Acute Kidney Injury.
Afolabi JM, Kanthakumar P, Williams JD, Kumar R, Soni H, Adebiyi A
Function (Oxford, England) 2023;4(4):zqad022
Function (Oxford, England) 2023;4(4):zqad022
Histopathological Evaluation of Pulmonary Thromboendarterectomy Specimens of Chronic Thromboembolic Pulmonary Hypertension.
Obikane H, Shimodai-Yamada S, Koizumi N, Ogino H, Nagao T, Hao H
Journal of atherosclerosis and thrombosis 2023 Nov 1;30(11):1661-1673
Journal of atherosclerosis and thrombosis 2023 Nov 1;30(11):1661-1673
Exercise protects aged mice against coronary endothelial senescence via FUNDC1-dependent mitophagy.
Ma L, Li K, Wei W, Zhou J, Li Z, Zhang T, Wangsun Y, Tian F, Dong Q, Zhang H, Xing W
Redox biology 2023 Jun;62:102693
Redox biology 2023 Jun;62:102693
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4.
Zhang J, Pan L, Zhang Q, Zhao Y, Wang W, Lin N, Zhang S, Wu Q
FEBS open bio 2023 Jun;13(6):1107-1124
FEBS open bio 2023 Jun;13(6):1107-1124
Endothelin-1 production via placental (pro)renin receptor in a mouse model of preeclampsia.
Mishima S, Mitsui T, Tani K, Ooba H, Mitoma T, Ohira A, Maki J, Kirino S, Eto E, Hayata K, Masuyama H
Placenta 2023 Jul;138:44-50
Placenta 2023 Jul;138:44-50
Different exercise training intensities prevent type 2 diabetes mellitus-induced myocardial injury in male mice.
Pei Z, Zhou R, Yao W, Dong S, Liu Y, Gao Z
iScience 2023 Jul 21;26(7):107080
iScience 2023 Jul 21;26(7):107080
The effect and mechanism of excessive iodine on the endothelial function of human umbilical vein endothelial cells.
Wang D, Li P, Liu L, Liu P, Zhou Z, Jin M, Li B, Li F, Chen Y, Shen H
Environmental toxicology 2023 Jan;38(1):136-145
Environmental toxicology 2023 Jan;38(1):136-145
Ufl1 deficiency causes skin pigmentation by up-regulation of Endothelin-1.
Wang K, Xu HN, Wang YW, Mao J, Liu D, Zhu XJ, Cong YS, Wang M
Frontiers in cell and developmental biology 2022;10:961675
Frontiers in cell and developmental biology 2022;10:961675
miR-351 promotes atherosclerosis in diabetes by inhibiting the ITGB3/PIK3R1/Akt pathway and induces endothelial cell injury and lipid accumulation.
Li H, Song D, Liu Q, Li L, Sun X, Guo J, Li D, Li P
Molecular medicine (Cambridge, Mass.) 2022 Sep 30;28(1):120
Molecular medicine (Cambridge, Mass.) 2022 Sep 30;28(1):120
Macrophage-derived exosomal miR-4532 promotes endothelial cells injury by targeting SP1 and NF-κB P65 signalling activation.
Liu P, Wang S, Wang G, Zhao M, Du F, Li K, Wang L, Wu H, Chen J, Yang Y, Su G
Journal of cellular and molecular medicine 2022 Oct;26(20):5165-5180
Journal of cellular and molecular medicine 2022 Oct;26(20):5165-5180
Systems analysis identifies endothelin 1 axis blockade for enhancing the anti-tumor effect of multikinase inhibitor.
Hwang CY, Yu SJ, Won JK, Park SM, Noh H, Lee S, Cho EJ, Lee JH, Lee KB, Kim YJ, Suh KS, Yoon JH, Cho KH
Cancer gene therapy 2022 Jun;29(6):845-858
Cancer gene therapy 2022 Jun;29(6):845-858
Curcumin improves the function of umbilical vein endothelial cells by inhibiting H(2)O(2)‑induced pyroptosis.
Yuan Y, Zhang C, He Y, Yuan L, Zhao Q, Liu Y, Long S
Molecular medicine reports 2022 Jun;25(6)
Molecular medicine reports 2022 Jun;25(6)
Roquin2 suppresses breast cancer progression by inhibiting tumor angiogenesis via selectively destabilizing proangiogenic factors mRNA.
Zhou M, Lu W, Li B, Yuan X, Liu M, Han J, Liu X, Li A
International journal of biological sciences 2021;17(11):2884-2898
International journal of biological sciences 2021;17(11):2884-2898
Cadmium exposure induces endothelial dysfunction via disturbing lipid metabolism in human microvascular endothelial cells.
Liang H, Yue R, Zhou C, Liu M, Yu X, Lu S, Zeng J, Yu Z, Zhou Z, Hu H
Journal of applied toxicology : JAT 2021 May;41(5):775-788
Journal of applied toxicology : JAT 2021 May;41(5):775-788
The lncRNA MALAT1 participates in regulating coronary slow flow endothelial dysfunction through the miR-181b-5p-MEF2A-ET-1 axis.
Zhao C, Zong Z, Zhu Q, Wang Y, Li X, Zhang C, Ma C, Xue Y
Vascular pharmacology 2021 Jun;138:106841
Vascular pharmacology 2021 Jun;138:106841
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Wang Z, Li Y, Yao J, Yu S, Yu H, Men L, Du J
The international journal of biochemistry & cell biology 2021 Dec;141:106111
The international journal of biochemistry & cell biology 2021 Dec;141:106111
Blocking mitochondrial cyclophilin D ameliorates TSH-impaired defensive barrier of artery.
Liu X, Du H, Chai Q, Jia Q, Liu L, Zhao M, Li J, Tang H, Chen W, Zhao L, Fang L, Gao L, Zhao J
Redox biology 2018 May;15:418-434
Redox biology 2018 May;15:418-434
Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes.
Ha NH, Nair VS, Reddy DN, Mudvari P, Ohshiro K, Ghanta KS, Pakala SB, Li DQ, Costa L, Lipton A, Badwe RA, Fuqua S, Wallon M, Prendergast GC, Kumar R
Cancer research 2011 Dec 1;71(23):7259-69
Cancer research 2011 Dec 1;71(23):7259-69
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human ileum tissue were subjected to SDS PAGE followed by western blot with 12191-1-AP(EDN1 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Endothelin 1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Endothelin 1. This antibody recognizes human antigen. The Endothelin 1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
