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Protein structure
EDN1
Endothelin 1ET1
This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Top validated antibodies |
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| Invitrogen Antibodies |  MA3-005 |
41 references | Monoclonal |
WB
ICC
IHC
FC
RA
OA
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| Novus Biologicals | NB300-526 |
4 references | Monoclonal |
WB
ICC
IHC
FC
RA
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| GeneTex | GTX22786 |
1 references | Monoclonal |
WB
ICC
IHC
FC
RA
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| antibodies-online | ABIN152685 |
2 references | Monoclonal |
WB
ICC
IHC
FC
RA
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| LSBio | LS-C167623 |
Polyclonal |
WB
ICC
IHC
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