BS6722

antibody from Bioworld Technology, Inc
Targeting: REN
Provider product page for BS6722
Western blot
Immunohistochemistry

Antibody data

Product number
BS6722 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Renin polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human Renin.
Description
Renin is a highly specific endopeptidase that mediates the cleavage of the circulating substrate angiotensinogen to yield Angiotensin I. Angiotensin-converting enzyme I (ACE) then completes the conversion from Angiotensin I to Angiotensin II which is significant in the regulation of electrolyte balance and blood pressure. Sympathetic stimulation (ÉÇ1-adrenergic receptors), renal artery hypotension and decreases in sodium delivery to the distal tubules of the kidney signal the release of Renin. The Renin-Angiotensin system (RAS) is essential for regulating blood volume, arterial pressure and normal cardiac and vascular function. Renin is synthesized and secreted by modified smooth muscle cells in the juxtaglomerular apparatus (JGA) of the kidney. Expression of Renin in other tissues, including brain, has been verified although the homeostatic role it may play is yet to be firmly established.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
REN protein structure - BS6722 shown in red.