Tissue expression
Cell line expression
Protein structure

REN

Renin
 
This gene encodes renin, an aspartic protease that is secreted by the kidneys. Renin is a part of the renin-angiotensin-aldosterone system involved in regulation of blood pressure, and electrolyte balance. This enzyme catalyzes the first step in the activation pathway of angiotensinogen by cleaving angiotensinogen to form angiotensin I, which is then converted to angiotensin II by angiotensin I converting enzyme. This cascade can result in aldosterone release, narrowing of blood vessels, and increase in blood pressure as angiotension II is a vasoconstrictive peptide. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause hyperuricemic nephropathy familial juvenile 2, familial hyperproreninemia, and renal tubular dysgenesis. [provided by RefSeq, May 2020]
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885 antibodies from 40 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Invitrogen Antibodies
42 antibodies
R&D Systems
7 antibodies
Novus Biologicals
36 antibodies
Biorbyt
106 antibodies
NovoPro Bioscience Inc.
14 antibodies
Affinity Biosciences
3 antibodies
antibodies-online
211 antibodies
GeneTex
20 antibodies
Cusabio Biotech Co., Ltd
7 antibodies
Abnova Corporation
10 antibodies
FineTest Biotech
1 antibody
NSJ Bioreagents
2 antibodies
OriGene
32 antibodies
Aviva Systems Biology
4 antibodies
Bioworld Technology, Inc
2 antibodies
St John's Laboratory
6 antibodies
Sino Biological Inc.
8 antibodies
Signalway Antibody LLC
1 antibody
Boster Biological Technology
3 antibodies
Molecular Innovations
18 antibodies
Abgent
3 antibodies
Acris Antibodies GmbH
6 antibodies
MyBioSource
39 antibodies
RabMAbs
4 antibodies
Creative Diagnostics
7 antibodies
Atlas Antibodies
1 antibody
Creative Biolabs
42 antibodies
GenWay
6 antibodies
ProSci
3 antibodies
Abbexa
13 antibodies
RayBiotech, Inc.
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Cell Signaling Technology, Inc
1 antibody
United States Biological
33 antibodies
Leading Biology
5 antibodies
EMD Millipore
2 antibodies
MilliporeSigma / Merck KGaA
3 antibodies