PREN4B5E3

antibody from Molecular Innovations

Targeting: REN

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

PREN4B5E3

Provider

Molecular Innovations

Product name

Anti-REN

Antibody type

Monoclonal

Antigen

Recombinant full-length protein

Description

Inhibitory monoclonal antibody to human prorenin, clone 4B5-E3. Inhibitory mouse monoclonal antibody directed to human prorenin (Patent Pending). This antibody recognizes and binds only to prorenin. It does not bind or otherwise interact with active renin. Blocks proteolytic conversion of prorenin to renin by catalytic amounts of trypsin (unpublished data). Binding epitope is within amino acid residues 30-43 (MARLGPEWSQPMKR) of prorenin. Strongly blots prorenin under non-reducing and reducing conditions. No cross reactivity with mouse or rat prorenin. IgG fraction purified by immobilized Protein A. Clone 4B5-E3, isotype IgG2b.

Reactivity

Human

Host

Mouse

Epitope

MARLGPEWSQPMKR (amino acid residues 30-43 of the prosegment of prorenin)

Isotype

IgG

Antibody clone number

4B5-E3

Vial size

1000 µl

Concentration

1 mg/ml

Storage

-70 C