130-10066-500

BIRC3 antibody from RayBiotech, Inc.
API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49
Western blot
Recommended by provider
ELISA
Recommended by provider

Antibody data

Product number
130-10066-500
Provider
RayBiotech, Inc.
Product name
Rabbit Anti-Human TNi
Provider product page
RayBiotech, Inc. - 130-10066-500
Antibody type
Polyclonal
Antigen
Recombinant protein derived from human TnI.
Description
Troponin I, one of 3 subunits that form the troponin complex of the thin filaments of striated muscle, is the inhibitory component of troponin. Troponin, in conjunction with tropomyosin, functions as a molecular switch, regulating muscle contraction in response to changes in the intracellular Ca2+ concentration. Troponin consists of three subunits: the Ca2+-binding subunit troponin C (TnC), the tropomyosin-binding subunit troponin T (TnT), and the inhibitory subunit troponin I (TnI) . Unlike other contractile proteins, the cardiac isoform of troponin I (TnIc) is expressed only in cardiac muscle and therefore offers a model for cardiac-specific expression. It is also subject to developmental regulation with increased expression occurring at the time of birth. TnIc, a sensitive and specific marker of myocardial cell injury, is useful in diagnosing and assessing prognosis in acute coronary syndromes. Studies report that TnIc is elevated in severe heart failure and may predict adverse outcomes. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography.
Reactivity
Human
Host
Rabbit
Antigen sequence
This antibody was produced from a r
abbit immunized with the immunogen.
The IgG fraction was purified from
rabbit serum by ammonium sulphate
precipitation followed by Protein A
/G affinity chromatography.
Isotype
IgG
Vial size
500 µg
Handling
Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1x PBS to a final concentration of 1 mg/ml.
Provider Type Product Number
- No reagents -