Tissue expression
Cell line expression
Protein structure
BIRC3
Baculoviral IAP repeat containing 3API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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Atlas Antibodies | HPA002317 | 3 references | Polyclonal |
WB
ICC
IHC
|
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antibodies-online | ABIN2846885 | 2 references | Polyclonal |
WB
ICC
IHC
|
|
Novus Biologicals | NBP1-27972 | 2 references | Polyclonal |
WB
ICC
IHC
|
|
Invitrogen Antibodies | PA5-22997 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
R&D Systems | AF8171 | 10 references | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
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Recommended by provider