SPRY2

gene product
hSPRY2
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008]
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286 antibodies from 33 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
7 antibodies
Abnova Corporation
4 antibodies
antibodies-online
74 antibodies
LifeSpan BioSciences, Inc.
79 antibodies
Rockland Immunochemicals, Inc.
3 antibodies
NovoPro Bioscience Inc.
3 antibodies
Boster Biological Technology
3 antibodies
Abgent
2 antibodies
Biorbyt
15 antibodies
Proteintech Group
1 antibody
Aviva Systems Biology
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Acris Antibodies GmbH
1 antibody
Bioworld Technology, Inc
1 antibody
GeneTex
1 antibody
Creative Biolabs
5 antibodies
OriGene
3 antibodies
Invitrogen Antibodies
4 antibodies
Creative Diagnostics
3 antibodies
Atlas Antibodies
1 antibody
NSJ Bioreagents
1 antibody
R&D Systems
1 antibody
St John's Laboratory
3 antibodies
Bethyl Laboratories
2 antibodies
MyBioSource
2 antibodies
GenWay
1 antibody
ProSci
1 antibody
United States Biological
39 antibodies
Sigma-Aldrich
4 antibodies
Abbexa
3 antibodies
EMD Millipore
1 antibody