Tissue expression
Cell line expression

SPRY2

gene product
hSPRY2 
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Antigen sequence

Conjugate

Epitope

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
311 antibodies from 36 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
7 antibodies
Abnova Corporation
4 antibodies
Proteintech Group
1 antibody
LifeSpan BioSciences, Inc.
79 antibodies
antibodies-online
74 antibodies
Invitrogen Antibodies
15 antibodies
NovoPro Bioscience Inc.
3 antibodies
Abgent
2 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
NSJ Bioreagents
2 antibodies
Boster Biological Technology
3 antibodies
Biorbyt
15 antibodies
Cusabio Biotech Co., Ltd
1 antibody
Aviva Systems Biology
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Acris Antibodies GmbH
1 antibody
Bioworld Technology, Inc
1 antibody
GeneTex
1 antibody
OriGene
3 antibodies
Rockland Immunochemicals, Inc.
3 antibodies
Creative Diagnostics
5 antibodies
Atlas Antibodies
1 antibody
R&D Systems
1 antibody
St John's Laboratory
3 antibodies
Bethyl Laboratories
2 antibodies
MyBioSource
2 antibodies
Leading Biology
2 antibodies
Abbexa
6 antibodies
GenWay
1 antibody
ProSci
1 antibody
United States Biological
39 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
Creative Biolabs
9 antibodies
EMD Millipore
1 antibody