22248-1-AP
antibody from Proteintech Group
Targeting: ADARB1
ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, hRED1, RED1
Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 22248-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ADARB1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ADARB1 antibody (Cat. #22248-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Differential microRNA editing may drive target pathway switching in human temporal lobe epilepsy.
The Allelic Expression of RNA Editing Gene ADARB1 in Hepatocellular Carcinoma Treated with Transarterial Chemoembolization.
Atractylodes lancea volatile oils target ADAR2-miR-181a-5p signaling to mesenchymal stem cell chondrogenic differentiation.
Biological functions of RNA modification patterns that define tumor microenvironment and survival outcomes in testicular germ cell tumors.
Aberrant Expression of ADARB1 Facilitates Temozolomide Chemoresistance and Immune Infiltration in Glioblastoma.
Breakage of cytoplasmic chromosomes by pathological DNA base excision repair.
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs.
Lung fibrosis is induced in ADAR2 overexpressing mice via HuR-induced CTGF signaling.
A-to-I RNA editing of BLCAP promotes cell proliferation by losing the inhibitory of Rb1 in colorectal cancer.
Downregulated ADARB1 Facilitates Cell Proliferation, Invasion and has Effect on the Immune Regulation in Ovarian Cancer.
Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA.
Function of low ADARB1 expression in lung adenocarcinoma.
Lipopolysaccharide enhances ADAR2 which drives Hirschsprung's disease by impairing miR-142-3p biogenesis.
Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice.
Lau KEH, Nguyen NT, Kesavan JC, Langa E, Fanning K, Brennan GP, Sanz-Rodriguez A, Villegas-Salmerón J, Yan Y, Venø MT, Mills JD, Rosenow F, Bauer S, Kjems J, Henshall DC
Brain communications 2024;6(1):fcad355
Brain communications 2024;6(1):fcad355
The Allelic Expression of RNA Editing Gene ADARB1 in Hepatocellular Carcinoma Treated with Transarterial Chemoembolization.
Zeng J, Han L, Wang T, Huang L, Zheng Y, Zhang N, Li Z, Yang M
Pharmacogenomics and personalized medicine 2023;16:229-238
Pharmacogenomics and personalized medicine 2023;16:229-238
Atractylodes lancea volatile oils target ADAR2-miR-181a-5p signaling to mesenchymal stem cell chondrogenic differentiation.
Ye S, Si W, Qin W, Yang L, Luo Z, Li Z, Xie Y, Pan H, Li X, Huang Z, Zhu M, Chen D
Anatomical record (Hoboken, N.J. : 2007) 2023 Dec;306(12):3006-3020
Anatomical record (Hoboken, N.J. : 2007) 2023 Dec;306(12):3006-3020
Biological functions of RNA modification patterns that define tumor microenvironment and survival outcomes in testicular germ cell tumors.
Tang W, Qian J, Qian S
American journal of translational research 2022;14(9):6484-6503
American journal of translational research 2022;14(9):6484-6503
Aberrant Expression of ADARB1 Facilitates Temozolomide Chemoresistance and Immune Infiltration in Glioblastoma.
Lu C, Chen X, Yan Y, Ren X, Wang X, Peng B, Cai Y, Liang Q, Xu Z, Peng J
Frontiers in pharmacology 2022;13:768743
Frontiers in pharmacology 2022;13:768743
Breakage of cytoplasmic chromosomes by pathological DNA base excision repair.
Tang S, Stokasimov E, Cui Y, Pellman D
Nature 2022 Jun;606(7916):930-936
Nature 2022 Jun;606(7916):930-936
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs.
Kokot KE, Kneuer JM, John D, Rebs S, Möbius-Winkler MN, Erbe S, Müller M, Andritschke M, Gaul S, Sheikh BN, Haas J, Thiele H, Müller OJ, Hille S, Leuschner F, Dimmeler S, Streckfuss-Bömeke K, Meder B, Laufs U, Boeckel JN
Basic research in cardiology 2022 Jun 23;117(1):32
Basic research in cardiology 2022 Jun 23;117(1):32
Lung fibrosis is induced in ADAR2 overexpressing mice via HuR-induced CTGF signaling.
Soundararajan R, Varanasi SM, Patil SS, Srinivas S, Hernández-Cuervo H, Czachor A, Bulkhi A, Fukumoto J, Galam L, Lockey RF, Kolliputi N
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22143
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22143
A-to-I RNA editing of BLCAP promotes cell proliferation by losing the inhibitory of Rb1 in colorectal cancer.
Han F, Hu M, Zhang L, Fan X, Wang J, Lou Z, Wang S, Chen L, Ye Y, Ding Y, Jiao H
Experimental cell research 2022 Aug 15;417(2):113209
Experimental cell research 2022 Aug 15;417(2):113209
Downregulated ADARB1 Facilitates Cell Proliferation, Invasion and has Effect on the Immune Regulation in Ovarian Cancer.
Zhu W, Xu Z, Huang M, Wang X, Ren X, Cai Y, Peng B, Liang Q, Chen X, Yan Y
Frontiers in bioengineering and biotechnology 2021;9:792911
Frontiers in bioengineering and biotechnology 2021;9:792911
Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA.
Suzuki H, Matsuoka M
Journal of neurochemistry 2021 Aug;158(3):753-765
Journal of neurochemistry 2021 Aug;158(3):753-765
Function of low ADARB1 expression in lung adenocarcinoma.
Wang X, Xu Z, Ren X, Chen X, Wei J, Lin W, Li Z, Ou C, Gong Z, Yan Y
PloS one 2019;14(9):e0222298
PloS one 2019;14(9):e0222298
Lipopolysaccharide enhances ADAR2 which drives Hirschsprung's disease by impairing miR-142-3p biogenesis.
Peng L, Zhang H, Su Y, Shen Q, Du C, Xie H, Li H, Yan J, Shen Z, Jiang W, Xia Y, Xu X, Tang W
Journal of cellular and molecular medicine 2018 Sep;22(9):4045-4055
Journal of cellular and molecular medicine 2018 Sep;22(9):4045-4055
Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice.
Mirra A, Rossi S, Scaricamazza S, Di Salvio M, Salvatori I, Valle C, Rusmini P, Poletti A, Cestra G, Carrì MT, Cozzolino M
Scientific reports 2017 May 17;7(1):2033
Scientific reports 2017 May 17;7(1):2033
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ADARB1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ADARB1. This antibody recognizes human, rat antigen. The ADARB1 antibody has been validated for the following applications: ELISA, WB analysis.